Ch.11 Drugs used in skin disorders Flashcards
3 layers of skin
Epidermis, Dermis, Subcutaneous
3 routes that topical drugs absorb
-Through Statrum corneum
-Through Hair follicle
-Through Sweat or sebaceous glands
What is important for mediated shampooing
contact time
Topical nonsteriodal antipruritics
local anesthetics like lidocaine, tetracaine, benzocaine, pramoxine
Soothing agents for pruritus
oatmeal has soothing anti-inflammatory effects
Antihistamines calm _ and _ due to allergic reactions and sensitive skin
pain and itching
Topical corticosteroids for tx pruritus
hydrocortisone, flucoinolone, triamcinolone, betamethazone
What is seborrhea is
abnormal flaking or scaling of the epidermis (increased oil production= seborrhea oleasa) no increase oil production = seborrhea sicca
Keratolytics are an important group of _
antiseborrheics
What do keratolytics do
remove excess keratin and promote loosening of outer layers of epidermis , breakdown protein structure of keratin layer, permitting easier removal of this material
Sulfar as an antiseborrheic
keatolytic, antipruritic, antibacterial, anti fungal, and antiparasitic
SE: foul odor
Salicyclic acid as an antiseborrheic
keratolytic, antipruritic, and antibacterial
Coal tar as an antiseborrheic
keratolytic and degreasing
SE: may stain hair, odor, irritation, potential carcinogenic effect
Benzoyl peroxide as an antiseborrheics
keratolytic, antipruritic, antibacterial, degreasing, follicle flusher
Selenium sulfer as an antiseborrheic
keratolytic, degreasing, and anti fungal
