Ch.10 Drugs used in ophthalmic and otic disorders Flashcards
The ocular system is comprised of the _ and _
eyes and adnexa
Globe consists of
globe, choroid, retina
Adnexa consists of the surrounding structures:
orbit, eye muscles, eyelids, eyelashes, conjunctiva, and lacrimal apparatus
common ophthalmic disease
ulcerative keratitis
uveitis
glaucoma
KCS
conjunctivitis
Ophthalmic drugs must be absorbed into the _ chamber
anterior
Examples of topical anesthetics _ and _ are used to help perform comprehensive eye exams or removal of foreign material from the eye
proparacaine and tetracaine
_ _ is applied to the cornea (using sterile saline_ to assess any corneal defects (the stain is orange until it adheres to a corneal defect, where it appears green)
Fluorescein sodium
What do miotics do to the pupil
constrict it
Miotics are used to tx
open-angle glaucoma by increasing the outflow of aqueous humor (decreasing intraocular pressure)
Example of commonly used miotics
pilocarpine
What mydriatics do to the pupil
dilate it
Cycloplegics _ the ciliary muscles and minimize pain
paralyze
Examples of mydriatics
atropine, homatropine, phenylephrine, tropicamide, epinephrine
Carbonic anhydrase inhibitors decrease _ _ production
aqueous humor
Examples of carbonic anhydrase inhibitors
acetazolamide, dorzolamide, dichlorphenamide, and methazolamide
How do beta-adrenergic blockers affect production of aqueous humor
decrease
Examples of beta-adrenergic blockers
timolol and betazolol
_ are diuretics that decrease vitreous humor volume to rapidly decrease intraocular pressure
osmotics
Examples of osmotics
mannitol and glycerin
Drugs used to tx uveitis
flurbiprofen ophthalmic, tx underlying condition
Examples of drugs used to tx KCS
-Artificial tears
-Antibiotic steroid tx
-Immunomodulators such as cyclosporine
Tx of ulcerative keratitis (corneal ulceration)
Anti-infective opthalmic drops/ointment (bacitracin, neomycin, polymyxin, erythromycin, etc.)
Serum
Atropine sulfate (cycloplegic)
Other drugs used to tx ocular disease
Antibiotics
Antifungals
Antivirals
Corticosterioids
NSADIS
Side effects of otitis interna
head tilt toward infected side, ataxia, nausea, vomiting