Ch. 8 Gene Expression Flashcards

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1
Q

process of using instructions carried by a gene to build a particular protein

A

protein synthesis

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2
Q

coping of DNA into RNA. happens inside nucleus

A

transcription

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3
Q

enzyme that binds to promoter to begin transcription. unzips DNA to make RNA template. creates complementary messenger RNA (mRNA)

A

RNA polymerase

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4
Q

mRNA is blueprint for protein. happens in cytoplasm

A

translation

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5
Q

made of rRNA. large and small subunit come together and mRNA is threaded between them

A

ribosome

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6
Q

carries specific amino acid on the anticodon

A

transfer RNA (tRNA)

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7
Q

3 nucleotides long and encode a particular amino acid on the mRNA

A

codon

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8
Q

3 nucleotides long. bind to codon if match. complementary to codon. adds amino acid to growing polypeptide

A

anticodon

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9
Q

codon that does not code for an amino acid. growing protein is then released and folds upon itself and moves to required location within cell

A

stop codon

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10
Q

determines which mRNA codons code for which amino acids

A

genetic code

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11
Q

AUG

A

start codon

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12
Q

UAA, UAG, UGA

A

stop codon

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13
Q

changes to DNA sequence

A

mutations

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14
Q

mutation has no effect on protein

A

neutral mutation

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15
Q

insertion or deletion of nucleotides shifts the reading frame

A

frameshift mutation

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16
Q

triplet groupings of nucleotides

A

reading frame

17
Q

turning a gene on or off in response to cells needs

A

regulating gene expression

18
Q

undifferentiated and do not perform a specific function

A

stem cells

19
Q

using stem cells to produce healthy tissues to replace damaged tissues

A

therapeutic cloning

20
Q

stem cells are able to become any other cell

A

totipotent

21
Q

determining nucleotide base sequence for the entire human genome and the location of each of the genes

A

human genome project

22
Q

important genes are often common in many organisms other than humans

A

model organism

23
Q

replacing defective genes with functional genes

A

gene therapy

24
Q

supplying embryo with normal versions of defective gene to be replicated. making most cells carry the functioning gene

A

germ-line gene therapy

25
Q

fix or replace defective protein in only affected cells. introduce functional version to individual defective cell in lab. allow it to reproduce and the place copies of healthy cell in decreased person

A

somatic cell gene therapy

26
Q

genetic mutation that results in absence of important enzymes and severley weakens immune system. any infection or exposure can kill or disable affected person

A

sever combined immunodeficiency (SCID)

27
Q

making an exact copy of an entire organsim

A

cloning

28
Q

removing nucleus of egg cell and fusing the cell to another cell of another organism. treated egg cells are then placed in a uterus to develop

A

nuclear transfer