Ch. 5 DNA Synthesis, Mitosis, and Meiosis Flashcards
uncontrolled cell division
cancer
unregulated cell division that leads to a pileup of cells that form a lump. mass of cells with no apparent function
tumor
tumor that stays in one place and doesnt affect surrounding structures
benign tumor
tumor that invades surrounding tissue
malignant tumor
cells of malignant tumor break away and start new cancers at another location
metastasis
produce exact copies of themselves via cell division. offspring identical to parent. single celled organisms
asexual reproduction
requires genetic information from 2 parents. egg and sperm combine information at fertilization
sexual reproduction
instructions for building the proteins a cell requires. carried on DNA
genes
DNA wrapped around proteins. uncondensed before cell division. becomes condensed in short linear form to move easier and prevent getting tangled during division.
chromosomes
copy of a replicated chromosome. each is one DNA molecule
sister chromatid
where sister chromatid attach to each other. toward middle of chromosome
centromere
preceed cell division. double stranded is split and copied. new nucleotides are added to each original strand. creates 2 daughter DNA molecules, each containing a new and original strand
DNA replication
each new DNA is 1/2 conserved parental DNA and 1/2 is new
semiconservative DAP replication
enzyme that binds nucleotides to each other on new strand, moving along unwound DNA helix. catalyzes covalent bonds between nucleotids
DNA polymerase
life cycle of a cell
cell cyle
where normal cell spends most time. performs typical functions and produces its specific proteins. time spent in this phase depends on how frequent the cell divides (skin spends less time, nerve cells spend more time)
interphase. has G1, S, and G2
first gap of growth. organelles duplicate and cell grows larger.
G1 phase
synthesis of DNA and chromosomes replicate
S phase
second gap. grows and prepares for division. synthesis of proteins that aid mitosis
G2 phase
asexual reproduction. happens in all cells with a nucleus. prophase, metaphase, anaphase, telophase, and cytokenesis
mitosis
replicated chromosomes condense. microtubules forma nd grow, reaching from poles of cell, helping cell expand. nuclear envelope breaks down to give access to chromosomes. centrioles anchor one end of each microtubule to pole
prophase
replicated chromosomes line across equator of cell in single file. microtubules attach to chromosomes at centromere
metaphase
centromere spilt. motor protein pull sister chromatid to opposite poles.
anaphase
nuclear envelope redevelopes around new daughter nuclei. chromosomes uncondense
telophase
band of proteins encircle cell at equator and divides cytoplasm. contracts and pinches apart the two new cells. cell re enters interpase
cytokenesis
specialized sex cells. products of meiosis. have one chromosome from every pair
gametes
highly magnified picture of chromosomes arranged in pairs. usually from nuclei of WBCs stopped at metaphase. composed of sister chromatids and shaped like “X”. paired withmate of same size, shape, and centromere posistion
karyotype
22 pairs of nonsec chromosomes. homologous pairs
autosomes
one pair. X and Y chromosomes.
sex chromosomes
male sex chromosomes
XY
female sex chromosomes
XX
each member carries same genes along its length. (not same versions of gene)
homologous pairs
different versions of the same gene
allele
only on member of each pair is present in cell. egg and sperm cells
haploid (n)
2 sets of each chromosome is present. zygots and somatic cells
diploid (2n)
meiosis interphase
same as mitosis interphase. once DNA is replicated, it enters meiosis 1.
same as mitosis but product is 2 haploid daughter cells
meiosis 1
same as mitosis but product is 4 haploid daughter cells
meiosis 2
durign prophase 1. exchange of portions of chromosomes within homologous pairs. occurs several times on each pair during each meiosis
crossing over
2 genes on same chromosome. move together. increases genetic diversity by increasing number of gene combinations
linked gene
increases number of genetically distinct gametes. durring metaphase 1. changes way in which chromosomes will end up together in a gamete
random alignment
failure of chromosomes to separate. can be autosomes or sex chromosomes
nondisjunction
extra chromosme
trisomy
absence of chromosome
monosomy
down syndrome, patau syndrome, an dedwards syndrome
trisomy of 21, 13, and 18 chromosomes. nondisjunction of autosomes
turner syndrome, meta female, kleinfelter syndrome, and XYY
nondisjunction of sex chromosomes.