Ch. 10 Natural Selection Flashcards
tuberculosis
single-celled bacterium. destroys lung tissue
antibiotics
kill certain nonhuman bacterial cells
antibiotic resistant
must use second-line drugs
MDR-TB
multi-drug resistant tuberculosis
XDR-TB
extensive drug resistant tuberculosis
natural selection
inference based on 4 observations:
- individuals within populations vary
- some variation may be inherited
- populations produce more offspring than will survive
- survival and reproduction are not random
individual in populations vary
dog may have litter with some black and some white
variant
each different type of individual in a population
some variation may be inherited
resemblance between parent and offspring
populations produce more offspring that will survive
trees make million of seeds every year. capacity for reproduction far outstrips the environmental resources
survival and reproduction are not random
some variants are more likely to survive. fitness and adaptations
fitness
relative survival and reproduction of one variant compared to others
adaptations
traits that increase fitness in a particular environment
inference
favorable inherited traits tend to increase over time while unfavorable traits are lost
artificial selection
selection imposed by human choice. deliberately control survival and reproduction of organisms with favorable traits to change the population
natural selection in lab
looking for adaptations of populations to environments manipulated in lab settings
natural selection in wild populations
examples are drug resistant pathogens and the bill size in galapagos finches in response to drought
modern synthesis
union between genetics and evolution. gene mutations provide the variation needed for evolution
subtleties of natural selction
doesn’t cause evolution of perfect organisms.
- cant make new traits arise
- doesn’t result in perfection. only improves fitness in the current environment
- no progression toward a goal. only adapt to current environment
jury rigged design
adaptations using whatever underlying biology is available (‘thumbs’ on pandas)
directional selection
population traits move in a particular direction. typically leads to change in a population over time
stabilizing selection
populations tend to resist change in unchanging environments. the extreme variants are selected against and the average is in favor
diversifying selection
populations with 2 or more variants. likely if different subpopulations are experiencing different environments
tuberculosis and natural selection
- bacteria in population vary, every time reproduction occurs mutation can happen
- variation can be passed to offspring. drug resistant traits are coded in its DNA
- more bacteria are produced than survive. antibiotic treatment eliminate the majority
- survival isnt random. bacteria with traits making them more resistant are more likely to survive
drug resistance
patient stops treatment after symptoms are eliminated, leaving the more resistant bacteria still alive. the resistant strain reproduces and the disease returns and is much more difficult to control
stopping resistance
maintain drug therapy for several months, or use multiple drugs
combination drug therapy
drug cocktail therapy. the greater number of drugs used, the greater number of changes are required to become resistant