Ch 70 Muscle and tendon Flashcards

1
Q

What is the most common general location for a muscle strain?
What are the three stages of muscle strain?

A

Most common at musculotendinous junction, muscles which cross two or more joints appear predisposed

Three stages:
- Stage I: Myositis and brusing, architecture intact
- Stage II: Myositis and some tearing of the fascial sheath
- Stage III: Tearing of the fascial sheath, muscle fiber disruption and haematoma formation

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2
Q

What are the two processes of muscle healing?

A
  • Direct regeneration of myofibrils
  • Production of fibrous scar tissue

Myofibrils regenerate rapidly, provided the sarcolemmal nuclei have survived, complete repair if the endomysium is intact

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3
Q

muscle healing

A
  • Hematoma formation > inflammatory response, cellular infiltration and phagocytosis occurring 6 to 12 hours after injury.
  • 48 hours > invasion of capillaries and myoblast proliferation, followed by myofiber formation.
  • Fibroblast proliferation and collagen scar formation 4 to 6 days
  • filling the damaged area with a new collagen network by day 10.
  • Tissue strength increases rapidly up to day 14, when the entire process slows down.
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4
Q

Stage I and II injuries are more likely in the power group of muscles (6)

A
  • triceps brachii,
  • biceps femoris,
  • quadriceps femoris,
  • tensor fascia lata,
  • semitendinosus,
  • semimembranosus
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5
Q

Stage III injuries

A
  • long head of triceps brachii,
  • gracilis,
  • gastrocnemius,
  • tensor fasciae latae
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6
Q

What are the general principles of muscle treatment?

A
  • Maximise direct myofibril repair while minimising scar formation (excessive scar can reduce a muscles ability to produce tension by 50%)
  • 24 to 48hr > cold compresses and nsaid ( minimize the early disruptive effects of inflammation, edema, and swelling)
  • Early mobilisation essential for proper myofibril orientation and can be considered after day 5-10
  • Stage III injuries > surgery to eliminate any gaps and reduce scar, 2 to 3 days following injury

Stage I +/- stage II, good healing can be expected with direct growth of new muscle tissue

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7
Q

What are some common muscle injuries of the thoracic limb? (3)

A
  • Rupture of long head of triceps brachii (racing Greyhounds). Causes depression caudal and distal to scapula. Reattachment recommended
  • Avulsion of triceps brachii tendon of insertion. Primary reattachment to olecranon with immobilisation with transarticular ESF or olecranon- humeral screw
  • Rupture of serratus ventralis causing dramatic dorsal replacement of scapula (conservative vs tether the scapula to the thoracic wall via bone tunnels)
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8
Q

What are some common muscle injuries of the pelvic limb? (2)

A
  • Rupture of gracilis (Greyhounds, GSD, Foxhounds). Surgical repair or reattachment
  • Iliopsoas and pectineus muscle strain. Most common! Conservative management usually successful
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9
Q

What are the most common forms of muscle contracture in dogs? (5)

dt injury vs localized compartment syndrome???

A
  • Infraspinatus contracture (circumbuction and carpal flip with abduction of shoulder, adduction of elbow, lower limb abducted and externally rotated). Tendonectomy with release of surrounding fibrous tissue
  • Quadriceps contracture Neither the stifle nor the hock joint can be flexed, physiotherapy if early, sx usually unsuccessful > amputation
  • Gracilis and semitendinosus contracture (limb riase in jerk-like fashion with hyperflexion of the tarsocrural joint and internal rotation of metatarsus)
  • GSD 3- 7 years
  • condition becomes static
  • Conservative recommended dt recurrence after surgical intervention
  • Flexor carpi ulnaris muscle of puppies
  • Myositis ossificans (heterotrophic bone formation in muscles after trauma, most common at hip)

non painful, fibrotic replacement of the muscle fibers

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10
Q

What cells do tendon healing rely on?

A

Influx of fibroblasts to produce new collagen

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11
Q

How does tendon healing differ between paratenon-lined tendons and sheathed tendons?

A

Paratenon-lined:
- Can recieve vascular buds and an influx of undifferentiated cells from the paratenon and surrounding soft tissues.
- Better capacity for rapid healing
- Tendons of insertion of gastroc and triceps

Sheathed:
- Depend much more on intrinsic blood supply
- Digital flexor tendons

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12
Q

Tendon Healing

A
  • characteristically slow

depends on if:
1. paratenon lined or not
2. if Gap formation > When a gap is present, a scar is formed

  • first 4 to 5 days after repair > tendon ends lose holding power and then gradually increase in strength again during the next 2 weeks (fibroplasia and collagenization take place)
  • strength and resistance to gap> entirely achieved by the suture during the first 3 weeks
  • New tendon collagen requires strain or load for development of correct alignment > should be exposed at 3 weeks post repair.
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13
Q

What percentage strength does a tendon have at 6 weeks and 1 year after repair?
What percentage of normal capacity strain in placed on a tendon during normal muscle contraction?

A

6 weeks: 56%
1 year: 79%
Normal contraction places 25-33% of normal full capacity of strain. Thus, strength at 6 weeks should be sufficient to withstand limited exercise

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14
Q

How long must the suture material primarily maintain strength and resist gap formation during tendon healing?
What are the three main forms of suture patterns for tendon apposition?

A

Initial three weeks

Suture patterns:
- Locking loop
- Krakow
- Three-loop pulley

3LP has been compared with both a double Krackow, self-locking suture and two locking loops and the 3LP was more resistant to gap formation.

The addition of an epitendinous suture resulted in a twofold greater resistance to gap formation, greater load required before failure

suture tissue interaction is the weakest part of the repair, rather than the suture itself

negative affect on perfusion and vascularity?

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15
Q

Surgery aims/principles (2)

A
  • produce healing without gap formation
  • allows early loading to ensure correct collagen formation and alignment.

Kirschner wires through the body of the tendon away from ends, Monofilament synthetic long-term absorbable or nonabsorbable, holding suture patterns are required to resist pull-out, ends of the tendon are carefully debrided> apposition to ensure that the gap has been eliminated
Immobolise ESF, CAST, TA screw practically for 6 weeks

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16
Q

What are some common tendon injuries in small animals? (4)

A
  • Superficial and deep digital flexor tendon laceration
    above or below the metacarpal or metatarsal foot pad (if below may need to repiar 8 x tendons)
    common mistake is to fail to identify the deep digital tendons > present with flattened digits (dropped foot) or with a painful sore on the metatarsal pad
  • Common calcaneal tendon injury (most common)
  • tendon of origin of biceps brachii (Partial or full avulsion, Medial displacement in greyhounds, miniature Poodle and a Border Collie)
  • long digital extensor tendon (avulsion or displacement) immature large-breed dogs, joint effusion and lameness, Surgical exploration with reattachment of the tendon
17
Q

Ex vivo biomechanical characteristics and effects
on gap formation of using an internal fixation plate
to augment primary three-loop pulley repair
of canine gastrocnemius tendons
Yi-Jen Chang 2022

A

48 cadaveric GT
2-0 polypropylene with a 3LP repair alone or a 3LP repair augmented with a veterinary cuttable plate
Yield, peak, and failure loads were all significantly increased for the 5VCP and 7VCP group
viable surgical option to increase the strength of the tenorrhaphy in dogs. However, in vivo studies evaluating the effects of plate augmentation on the tendon blood supply and progression of healing are needed prior to clinical application.

18
Q

Loop diameter of a modified Kessler locking-loop
suture affects in vitro tensile strength and gapping
characteristics of canine flexor tendon repairs
Yi-Jen Chang 2022

A

2-0 polypropylene in a LL pattern
with loops measuring 1, 2, 3, or 4 mm in diameter
(96%) of constructs failing because of suture breakage.
Loop diameters > 3 mm are recommended when the size of the tendon allows

Further studies are necessary
to determine the clinical relevance of these findings
and the role of loop diameter on tendon blood supply
and healing in vivo.

Increasing the loop diameter increases the tensile strength and resistance to gap formation

increasing the number of loops without
increasing the volume of tissue engaged

Duffy et al: LL from 4-0 or 5-0 to size 0 or 2-0 polypropylene was an important
factor, conferring significantly increased tensile
strength to repaired canine tendons.

19
Q

Hybrid, transarticular external fixation with platelet-rich
plasma injection as a treatment for partial calcaneal tendon
disruption in dogs without primary tenorrhaphy
Boharski 2024

vs

A

Retrospective. 11. TA-ESF + PRP for calcaneal disruption without repair
Five dogs returned to full, pain free function (5/11 = 45%).
Five dogs had an acceptable, One unacceptable outcome
64% pin morbidity, 5/11 major

The lack of a validated survey tool for outcomes
humans: A large, randomized, prospective, placebo-controlled study
evaluating PRP injection against a saline placebo in patient-reported function and quality of life showed that PRP offered no benefit to patient outcome

20
Q

Investigation
of the effects of two-, four-, six- and eight-strand suture repairs on the biomechanical properties of canine gastrocnemius tenorrhaphy constructs
Yi-Jen Chang 2021

ajvr duffy

A

56 cadaveric
increasing the number of suture strands crossing the repair site significantly increases the tensile strength of canine gastrocnemius tendon repair constructs and their resistance to gap formation

further study: tendon glide function, blood supply, healing, and long-term clinical function

21
Q

Effect of epitendinous suture caliber on the tensile strength of repaired canine flexor tendons
Duffy 2021

A

60 cadaveric superficial digital flexor tendons
simple continuous circumferential ES

Yield, peak, and failure loads for SDFT repair constructs were positively correlated with ES caliber and did not differ between the size-0 and 2-0 groups
suggested size-0 and 2-0 sutures should be considered when placing an ES for flexor tendon repairs in dogs

failure mode: finer suture break, thicker suture pull through tendon

22
Q

Assessment of skin staples for augmentation of core tenorrhaphy in an ex vivo model of canine superficial digital flexor tendon laceration
Yi-Jen Chang 2020

duffy

A

core tenorrhaphy only and those in which the core tenorrhaphy was augmented with skin staples or a continuous Silfverskiöld cross-stitch (SXS) suture pattern.

inferior to epitendinous placement of SXS sutures. Further research is necessary before skin staples are used

23
Q

Retrospective multicentre evaluation
of common calcaneal tendon injuries in
66 cats. Part 2: treatment, complications
and outcomes
Thomas C Häußler1

A

Most cats (86%) were free of lameness at the long-term evaluation, with an overall successful clinical
long-term outcome of 84.9%, according to the owner questionnaire.
11 cats had conservative tx
ESF had&raquo_space;> mobidity than CT screw
short-term complication rate was
41.3%, the minor complication rate was 33.3% and the major complication rate was 7.9%,

Surgically treated cats had a slightly better long-term outcomes.
the conservatively managed had a successful long-term outcome in (81.8%)

24
Q

Meutstege introduced a classification system of canine
CCT injuries

A

Type I: A complete tear of all CCT parts
Type IIa: Musculotendinous ruptures
Type IIb: rupture with intact paratenon
Type IIc: gastrocnemius avulsions without (SDFT)
Type III: tendinosis or peritendinitis

25
Effect of calcanean bone-tunnel orientation for teno-osseous repair in a canine common calcanean tendon avulsion model Beamon 2022 | duffy
Results: The only difference detected consisted of TT constructs yielding at loads 25% higher than MT constructs (P = .027). Conclusion: Although yield loads were lower in MT constructs than other groups, the bone-tunnel anchoring techniques tested here did not appear to influence the biomechanical properties or gapping characteristics of tenoosseous repairs in this canine CCT avulsion model.
26
Rupture of the gastrocnemius muscle at its distal musculotendinous junction: conservative treatment and outcomes in 11 dogs Boyd 2023 | NZVJ
diagnosis was confirmed with ultrasound or MRI in six dogs All dogs were managed conservatively, either with complete confinement alone (n = 10; median 9 weeks), external coaptation alone (n = 1), or a combination of both (n = 4). A good (persistently increased tibiotarsal standing angle > partial plantigrade) to excellent outcome was achieved for all cases in this cohort Currently, there is no consensus on the treatment of DGMJR in dogs. All sporting dogs had an excellent outcome. In contrast, all companion dogs had a shorter duration of complete confinement and some form of coaptation (Table 2) and achieved a good outcome. in humans: almost uniformly non-surgical regeneration of functional tissue or by the proliferation of fibrous tissue to span the defect; a combination of both occurs in high-grade muscle injuries The predominance of one form of healing over the other can be influenced by the load, or lack thereof, placed through the healing tissues in
27
Calcaneotibial screws for immobilisation of the tarsocrural joint of dogs in extension: effect of the angle of screw placement on the force to failure in a canine cadaveric model S Devereux 2021 | NZVJ
Twelve pairs of cadaveric hindlimbs A calcaneotibial screw placed at an angle approximately perpendicular to the long axis of the calcaneus, has a higher force to failure under axial loading than a calcaneotibial screw that is placed at an angle approximately perpendicular to the tibia, in a canine cadaveric model. constructs were tested for load to failure rather than cyclic loading. likey due to increased Surface area no bending or breakage of screws during the force testing suggesting that the screws pulled out of the tibia before a high enough force was achieved to bend or break the screw between
28
Fibrotic myopathy and contracture of the caudal thigh musculature: a prospective study of 41 dogs (2019–2022) Sarah A. Wilson 2023
Inherited familial risk for fibrotic myopathy in the GSD was supported by pedigree analysis Intensive rehabilitation and physical therapy have been recommended to try to slow the progression of contracture and combat pelvic limb muscle atrophy. Recurrence of lameness within 3 to 5 months of surgical treatment is typical.5 Subsequent surgical treatment has a shorter time to recurrence.5 Treatment with autologous adipose-derived stem cells injected into the lesion as well as IV subjectively reported long-term resolution in 4 of 11 dogs.7 Comorbidities were common in the dogs of this report. The most frequently occurring comorbidity was spinal pathology, such as lumbosacral disease, intervertebral disc disease, and spinal osteoarthritis,
29
Biomechanical Comparison of a 3-Loop Pulley and a 4-Loop Pulley Suture for Tenorrhaphy in the Canine Gastrocnemius Tendon Kadie L. O’Byrne 2022
Randomized, cadaveric, biomechanical study of 30 canine gastrocnemius tendons. 2–0 polypropylene A 4LP pattern was biomechanically superior to a 3LP pattern, as demonstrated by a greater load required to form both a 1 and 3mm gap and a greater load for failure Ideally, gap formation should be less than 1mmto reduce the occurrence of scar formation a gap greater than 3mm did not change with time, indicating that a gap of 3mm or more prevents accrual of strength and stiffness, The 3LP has been compared with both a double Krackow, self-locking suture and two locking loops.9,10,12,13 and the 3LP wasmore resistant to gap formation.12 While the 3LP better resisted gap formation than the double locking loop, when compared with the double Krackow, the load required to form a 3mm gap was 21.37N greater compared with the 3LP The addition of an epitendinous suture resulted in a twofold greater resistance to gap formation, greater load required before failure and also resulted in suture breakage becoming a source of construct failure, rather than suture pull through alone. This supports previous findings that the suture tissue interaction is the weakest part of the repair, rather than the suture itself negative affect on perfusion and vascularity needs to also be considered.
30
tendon repair factors 1. suture diameter 2. loop size (LL) 3. number of loops (3LP) 4. addition of epitiendinous suture 5. number of suture strands across the tenorrhaphy 6. True locking sutures may provide greater purchase of collagen fibrils
31
Biomechanical analysis of accessory tendon graft augmentation for primary gastrocnemius tendon reconstruction in dogs Duffy 2021
Randomized, ex vivo, biomechanical. Population: Twenty-two Autologous ATG augmentation as an adjunct to primary GT repair increased yield, peak and failure forces The accessory tendon (AT) formed from the tendinous contributions of the gracilis, biceps femoris, and semitendinosus muscles >> which may be damaged concurrently in cases affected by degenerative disease or laceration injury augment the primary sutured repair include the reported use of tensor fascia lata,17 semitendinosus muscle,7 and flexor digitorum lateralis (FDL) grafts
32
Duffy
33
Prevalence of mineralisation of the tendon of the supraspinatus muscle in non-lame dogs R. Abbey* and R. Pettitt 2021
dog with with no history of lameness. Supraspinatus mineralisation was detected in four out of 99 dogs (4%), unilateral The prevalence of supraspinatus mineralisation was low in this population of non-lame dogs. This low level when compared to the higher prevalence level found in lame dogs, suggests that supraspinatus mineralisation could be associated with lameness in dogs either as an indirect result of lameness or as a primary cause The prevalence of mineralisation of the supraspinatus tendon in lame dogs has been reported as 24.7% (22 out of 89) in one study (Maddox et al. 2013) although it is not clear if the mineralisation was a cause of lameness or a result of the change in biomechanics due to an altered gait. the significant pathology was more often not in the shoulder (52/94 dogs)
34
Influence of barbed epitendinous sutures combined with a core locking-loop suture to repair experimental flexor tendon lacerations Adam C. Eby 2020 | duffy
Study design: Ex vivo, experimental study. Sample population: Eighty (n = 16/group) canine superficial digital flexor tendons (SDFT). continuous-locking epitendinous pattern Clinical significance: Stratafix barbed suture eliminates the requirement for knot tying and seems to be equivalent to smooth monofilament suture when used as an ES in this pattern. In human surgery of the distal extremities, ES use can increase repair strength by up to 50% and has been shown to decrease repair failures by 84%.
35
Effect of partial vs complete circumferential epitendinous suture placement on the biomechanical properties and gap formation of canine cadaveric tendons Daniel J. Duffy 2020
Study design: Ex vivo, biomechanical study. Sample population: Thirty-six Addition of a complete circumferential ES with a single or double knotting technique increased the biomechanical strength of normal tendon repairs while reducing gap formation compared with partial ES placement alone more even force distribution and higher strength vs partial
36
Biomechanical comparison of three epitendinous suture patterns as adjuncts to a core locking loop suture for repair of canine flexor tendon injuries Christina J. Cocca 2019
comparison of epitendinous suture techniques for canine flexor tendon injury repaired with LL, LL + simple continuous ES, LL + Silfverskiöld cross-stitch ES, and LL + interlocking horizontal mattress ES. - epitendinous suture → increased strength and resistance to gap formation - Yield, peak, and failure forces increased by 2.5-fold, two-fold, and twofold, respectively - no difference between patterns - addition of epitendinous suture more important than pattern should be investigated in vivo to address their effect on tendinous healing, blood supply, glide function, and peritendinous adhesion formation prior to clinical implementation.
37
Effect of a continuous epitendinous suture as adjunct to three-loop pulley and locking-loop patterns for flexor tendon repair in a canine model Putterman 2019
Study design: Ex vivo biomechanical study. Sample population: Seventy-two cadaveric SDFT 3LP → better gap prevention than locking loop - overall yield force increased significantly by epitendinous suture - LL subjectively → better approximation
38
Clinical outcomes after common calcanean tendon rupture repair in dogs with a loop-suture tenorrhaphy technique and autogenous leukoreduced platelet-rich plasma Kurt S. Schulz 2019
fiberloop FiberWire has greater stiffness and strength than comparably sized monofilament nonabsorbable suture.21 Braided multifilament suture Two dogs had major complications that were successfully revised. Follow-up was available in 11 of 12 dogs, with a median time of 12 months Owners scored function (COI) as 96.4% (range, 93.3%–97.8%) and quality of life as 94.6% (range, 92%–98.2%).