Ch 59 Surgery for HD Flashcards
categories for surgical management of canine hip dysplasia are? (3)
1) prophylactic (juvenile pubic symphysiodesis and pelvic osteotomy) goal = prevention of the development of secondary osteoarthritis that is often the sequela to hip joint laxity
2) salvage (Total hip arthroplasty and FHO) replace or eliminate the source of pain and, in the case of total hip arthroplasty, restore function
3) palliative (hip denervation)
Juvenile Pubic Symphysiodesis
anatomy
The pelvic symphysis has three peripheral ligaments: (1) the transverse or oblique fibrous fascia
at the dorsal aspect of the symphysis, which serves to strengthen the symphysis;
(2) the prepubic tendon
inserts at the cranial aspect of the pubic ramus
(3) the arcuate pubic ligament,
crosses the ischial arch and often becomes ossified
What kind of “joint” is the pelvic symphysis?
A synchondrosis which transforms over time to become a synostosis
Which end of the symphysis is larger?
Ischial portion is slightly larger
What kind of cartilage makes up the pelvic synthesis?
Hyaline cartilage - acts as the growth plate
Fibrocartilage - gradually replaced by bone
When does the pelvis symphysis start to ossify?
When is it complete?
Starts to ossify in a caudal to cranial direction beginning at 9-21 months
Completely ossified within 2-6yr
What is a JPS?
indictions? (3)
Application of electrocautery to the hyaline cartilage of the pubic symphysis resulting in heat-induced necrosis of the germinal chondrocytes
- advocated in dogs 12 to 20 weeks of age
- of predisposed breeds
- palpable hip joint laxity
How does a JPS effect acetabular growth?
Results in external rotation of the acetabulum in a ventrolateral axial direction
What is the ideal age for JPS?
12 - 20 weeks
25% treated dogs developed OA vs 83% of sham operated dogs
What muscles are partially elevated from the symphysis for JPS?
Gracilis and adductor muscles
What are the recommended electrosurgical settings for JPS?
500kHz current frequency
40W
- current applied via monopolar probe for 10-30 seconds
- every 2-3mm
- along cranial 1/3 - 1/2 of the symphysis
- sterile wood spatula depressor to protect the urethra OR assistant per rectum deviation of the rectum and urethra.
cranial aspect of the pubic symphyseal brim (pubic tubercle)
Rationale for JPS
- procedure is performed at an age when there is minimal likelihood of existing osteoarthritis
- minimally invasive procedure
studies:
- premature closure of the pubic symphysis results in shortening of the pubic ramus, thereby limiting circumferential growth of the ventral portion of the pelvic canal while dorsal growth remains unrestrained
- result is external rotation of the acetabulae in a ventrolateral axial direction
- increases coverage of the femoral heads
efficacy of JPS
- younger the puppy at the time of the procedure, the greater the change in femoral head coverage (greatest @ 12 weeks)
- hip joint laxity, as described by the PennHIP distraction index, maintained an improvement by 42% compared to control animals
Vezzoni et al
- 217 puppies aged 14 to 22 weeks
- Regardless of initial severity of hip dysplasia, as determined by hip joint laxity, treated puppies had less severe hip dysplasia than the control group at 12 to 18 months of age. The authors concluded that juvenile pubic symphysiodesis was efficacious when performed in patients with mild or moderate hip dysplasia (DI 0.40 to 0.69)
- based on DI, DAR, ortolani
- not effective in puppies with severe hip dysplasia
complications JPS
have not been reported
- excessive ventroversion of the acetabulum, resulting in ventromedial subluxation of the femoral head (if the procedure is performed when too young or no HD)
- pubic rami (shorter and thicker in treated dogs
- long-term complication is lack of efficacy (surgeon error or poor canididate)
What are the aims of TPO/DPO? (3)
- Reducing joint laxity
- Normalising joint stresses
- Improving joint congruence (axial rotation and lateralization of the acetabulum)
goal: prevent the development of phenotypic changes associated with the dysplastic hip
following D/TPO, laxity is expected to diminish
TPO + DPO
- triple pelvic osteotomy includes osteotomies of the pubis, the ischium, and the ilium
- double pelvic osteotomy does not include the osteotomy of the ischium.
- rationale for the development of the double pelvic osteotomy was to reduce the complications
subjective (observational studies and owner assessment) and objective (radiographs, force plate analysis, and kinematic analysis) studies have assessed outcomes following surgery.
biomechanical studies have shown that triple pelvic osteotomy can also reduce the magnitude of the force acting on the load-bearing portions of the acetabular rim and the femoral head and increase the contact area on which the force acts.
DPO patient selection
- laxity, consistent with early stages of hip dysplasia,
- without radiographic evidence of secondary osteoarthritis
- > > advocate for arthroscopic evaluation of the hip> more sensitive than RADS for identification of OA
- patients are younger than 1 year of age, with some authors suggesting a max 10 months
- in skeletally immature dogs, there is a capacity for improvement in joint congruity through uniform cartilage loading, thus preventing or limiting osteoarthritis
- Controversy hip joint laxity but without clinical signs attributable to hip dysplasia
- correlated development of osteoarthritis with early evaluation of hip joint laxity (i.e DI)
- reduction angle less than 15 degrees were unlikely to develop osteoarthritis
Patient Positioning, Approaches, and Procedure
pubic osteotomy
- down to the tendon of origin of the pectineus muscle at the iliopectineal eminence
- The tendinous origin is transected (avoid medial circumflex femoral artery and vein)
- section of pubis is excised (avoid the obturator nerve just caudal)
- sagittal saw, osteotome, or rongeurs
- Dissection of the tendon of insertion of the rectus abdominis muscle at the cranial is limited (risk of the caudal abdominal hernia)
- simultaneous bilateral, the pectineus mm is preserved VS a pubic symphysiotomy
ischial osteotomy (TPO)
- periosteal incision is made along the dorsal border of the ischium
- subperiosteal elevation of the internal obturator muscle (pudendal nerve along dorsal surface also elevated) + origins of the semimembranosus and semitendinosus muscles ventrally
- confirm that the osteotomy is directed toward the obturator foramen
- wire for stabilization is surgeon preference
ilial osteotomy
- gluteal “roll-up” (care cranial gluteal nerve, artery, and vein)
- osteotomy is performed just caudal to the sacroiliac joint, perpendicular to the long axis of the ilium or perpendicular to the long axis of the pelvis
- Caudodorsal angulation > ease lateral rotation of the caudal segment
- perpendicular to the long axis of the pelvis will allow lateral rotation of the acetabulum in the frontal plane, maintaining the alignment of the iliac segments.
- care is taken to protect the lumbosacral trunk as it courses medial to the body, and dorsal as** sciatic n** > protect with sponge or retractor
- Damage to the lumbosacral trunk may also occur during periosteal elevation medial to the iliac body
DPO
- decreased mobility of the caudal iliac segment > helpful to gently lever the caudal iliac segment using a long osteotome
- transection of the sacrotuberous ligament can reportedly ease the rotation
- acetabular ventroversion is generally 5 degrees less than that achieved when performing TPO
Plate fixation
- caudal portion of the plate is secured to the caudal segment, rotation bar screwed in the most cranial hole used to rotate the ilium ventrally while a screw, placed in the most ventral hole of the cranial part of the plate placed
- DPO: 25 and 30 degrees are most common.
What vessels need to be avoided during pubic osteotomy?
Nerve?
Deeper medial circumflex femoral artery and vein
Obturator nerve
What muscles need to be elevated from the ischium for ischial osteotomy of TPO? What structures need to be avoided?
Dorsal
- Internal obturator muscle
- Pudendal nerve
Ventral
- Semimembranosus
- Semitendinosus
- External obtruator muscle
What range of angles are typically available for TPO/DPO plates?
rotation degree?
20 - 45 degrees
The desired degree of rotation is generally 5 degrees greater than the measured angle of subluxation (add another +5 for DPO)
STUDY: Coverage by the DAR does not signifcantly increase over that achieve by a 20 degree plate
Rotation beyong 40 degrees is not advised (3)
- unlikely to yield further improved coverage,
- worsen pelvic canal narrowing
- may result in impingement of the dorsal acetabular rim on the femoral neck
dogs requiring more extreme rotation are not good candidates
locking vs non
- significantly lower incidence of screw pull-out occurs with use of locking plates
- however, risk of en bloc pull-out (i.e., avulsion of the lateral cortex along with the plate and screws)
studies performed before locking plates:
- lower incidence of screw migration is reported with the use of cancellous screws compared with cortical
- 9.2 times greater incidence of screw loosening occurred in hemipelves without a ventral plate
How have the use of locking plate and DPO effected the rates of screw loosening?
- DPO reduced screw loosening to 3.2% (from 6-36%)
- Locking plates reduced the rate of screw loosening to 0.4%
sacral screw purchase
- screw depth in the cranial segment subject of evaluation.
- decreased incidence of screw loosening has been reported when penetrate more deeply (i.e., >27 mm for the cranial two screws or >93% total sacral penetration)
- other studies report a lower incidence of screw loosening when the sacroiliac joint is not entered.
What is the reported complication rate after a TPO? What are the main complications?
35 - 70%
Screw loosening and pelvic canal narrowing
Complications of Pelvic Osteotomy (6)
advantages of DPO over TPO
1) screw pull out
- incidence of screw loosening DPO 3.2%
- compared with TPO 6% - 36%
- compared with locking plate 0.4%
- locking divergent screws, withstand the pull-out forces applied to the caudal part due to the recoil of the twisted ilium and ischium
2) Pelvic canal narrowing-
- greater for increasing rotation angles
- not noted in a retrospective study of DPO (geometry was maintained by the intact ischium)
- narrowing can occur following bilateral TPO (lead to constipation or obstipation)
3) stranguria
- following bilateral TPO
- tends to be a transient phenomenon
- unknown cause (pelvic plexus or pudendal n damage??)
4) Excessive femoral head coverage by the dorsal acetabular rim
- coverage increased over time, 60-80%
- may be due to postoperative increased lateral rotation associated with pelvic canal narrowing
- not seen in DPO
5) Incomplete fracture of the ischial table
6) Ineffective control of hip dysplasia
- progression of osteoarthritis
- improper case selection
- inadequate acetabular ventroversion
Total Hip Arthroplasty
- Despite advances in cementing techniques, concerns about cement failure and associated implant loosening persist
- significant majority of canine total hip implants are cementless prostheses; however, cemented continue to play a significant role in veterinary hip replacement
- design and implantation require consideration of a variety of issues, including implant materials, tribology, means of fixation, and joint kinematics
How do metallic grains effect THR implant strength?
List manufacturing methods of increasing implant strength
The smaller the metallic grain, the stronger the implant
Manufacturing methods to srengthen implants:
- Forging
- Investment casting
- Hot isostatic pressing
- Cold working
- Heat working
Metallic Femoral Stem Materials
- stainless steel, cobalt-chromium alloys, titanium, and titanium alloys
- elasticity of implants is based on their stress-strain curve, and the elastic modulus is measured in pascals
- important not only in terms of the strength and stiffness but also with respect to the interaction of the implants with the bone and bone cement
- greater the elastic modulus mismatch between apposing surfaces, the greater the risk for development of wear debris or stress shielding
- Stainless steel is rarely used in total hip implants today
What is the elastic modulus of stainless steel, cobalt chromium and titanium?
Stainless steel and cobalt chromium = approx 200GPa
Titanium = approx 100GPa
What is stress shielding?
- Occurs when implant is stiffer than bone, preventing adequate load transfer to the bone,
- resulting in bone resorption due to relative disuse atrophy leading to implant loosening
What metals are in 316L stainless steel? (4)
Iron
Chromium
Nickel
Molybdenum
What metals are in cobalt alloys? (3)
What THR implant use this?
Chromium
Molybdenum
Nickel
Implants:
- BioMedtrix (BFX anf CFX)
- Very hard with excellent wear and corrosion resistance
What is the most common titanium alloy?
Which THR implant uses this?
Titanium is highly biocompatible
Ti6Al4V
Stronger, good fatigue resistance compared to pure titanium
More prone to wear debris than cobalt alloys
Implant
- Zurich Cementless (Recently switched to Ti6A14Nb)
- helica
What is tantalum?
A metal that can be fabricated with a porosity and elastic modulus similar to those of cancellous bone
What is tribology?
study of friction, wear, lubrication, and the design of bearings; the science of interacting surfaces in relative motion.
What is the acceptable linear wear rate in people?
0.1mm/year
Dogs showed a significantly lower volumetric wear that is seen in humans however dogs had a more severe bony reaction (osteolysis) to the debris
Bearing Surfaces
hip prostheses have bearing surfaces of polyethylene (on the acetabular side) and metal (on the femoral side)
- development of wear debris at articulating surfaces can result in osteolysis and aseptic loosening
- Implant wear can be evaluated by linear or by volumetric means.
- Linear > measured radiographcally based on a known starting width of the bearing surface.
- Volumetric > based on orthogonal radiographic or three-dimensional CT measurements
- Wear debris can be generated at bearing surfaces by a variety of means: adhesion, abrasion, erosion, corrosion, and fatigue.
Gravimetric testing requires the collection of wear debris
ideal bearing surface? (4)
- low friction,
- low wear debris generation,
- biocompatible,
- damage resistant.
List the 5 main ways in which wear debris can be generated
-
Adhesive wear (material from the softer bearing surface is transferred to the opposing surface and breaks free > cold welding, shear strength of the “cold” weld must be greater than the surface strength of the polyethylene)
2.** Abrasive wear** (irregularity on a hard surface damages the opposing surface or third-body wear/bone particle) - Fatigue wear ( Cyclic loading causing cracks/microcracks or subsurface delamination)
- Erosive wear (Solid particle erosion, impingement wear > if the prosthetic femoral neck contacts either the polyethylene liner or the metallic shell of the acetabular component)
- Corrosive wear ( galvanic corrosion - oxidation that generally results from interactions of disimilar metals)
Polyethylene and PEEK (cups)
primary acetabular bearing surface
- Ultra-high-molecular-weight polyethylene is a good low-friction surface, but it is prone to generation of wear debris
- polyetheretherketone is a semi-crystalline thermoplastic
biomedrix
- Highly Crosslinked and Vitamin E Stabilized UHMWPE
Kyon
- PEEK acetabular inlay
ceramic
Kyon - Zurich
- ceramic head > Zirconia Toughened Alumina
Under what circumstances is the greatest amount of wear debris created?
Titanium bearing surface with a cemented prosthesis
Metals
Cobalt-chromium
- CFX
- implants generate less wear debris than titanium alloys
- wear debris from cobalt-chromium is cytotoxic.
Titanium alloy
- wear debris is more inflammatory than cobalt-chromium
cementless systems now use titanium alloys (kyon, helica, biomedrix)
Surface Coatings for Metallic Heads
Titanium nitride (Ti-N) ceramic
- demonstrated substantial reductions in wear rates
- scratching of the Ti-N coating during surgical implantation and wear-through
Diamond-like carbon
- very low friction, have excellent wear and corrosion resistance, and are biologically inert
used in older generations Zurich Cementless hip
surface coatings for stems
Kyon
- Porous titanium and hydroxyapatite coating
- Calcium phosphate, mineral phase of bone is osteoconductive
Helica
- titanium alloy rough blasted
BFX
- EBM Titanium, , Electron Beam Melting > metal powder is fused layer by layer in a high vacuum using the computer model of the implant.
- porous surface is printed as an integral part of the stem, instead of making use of a spray or coating
histroically: plasma spray (for titanium) and beaded coating (chrome-cobolt) technologies had been used to achieve a stable press-fit
Biologically Active Surface Coatings
Hydroxyapatite
- osteoconductive and provides a calcium phosphate base for the deposition of bone.
- deposited on roughened or porous surfaces by plasma spraying.
- enhance bone ingrowth
- reported to prevent the migration of wear debris
- kyon
Bisphosphonate
- prevent periprosthetic osteoclastic bone resorption. - direct influence on osteoblasts
- dogs used in studies on prevention of aseptic loosening
- not commercial in vet
Ceramics
What forms of ceramic used in THR in dogs?
What are the benefits?
- are harder than metal
- Because of the very high elastic modulus of ceramic (approximately 300 times greater than cancellous bone), metal backing is necessary to prevent aseptic loosening secondary to modulus mismatch.
Zirconia (6th gen Kyon)
Wear products are locally inert
Hydrophilic crating a virtaully frictionless fluid-film lubrication
Metal-on-polyethylene > common commercially available articulation for vet
ceramic -on- PEEK > Kyon
However, production of wear debris and secondary osteolysis and aseptic loosening remain major problems.
metal-on-metal > should have minimal wear debris generation, however concerns regarding metallosis and a form of delayed-type hypersensitivity called aseptic lymphocyte-dominated vasculitis-associated lesion
Methods of Fixation
what (3) immediate methods? and (3) non-press-fit options?
for immediate, initial fixation > cemented (PMMA), cementless, and hybrid systems.
- interfaces between different materials include implant-bone, implant-cement, and cement-bone.
- Load transfer occurs at these interfaces, and the elastic modulus of each component determines how much load each component must bear.
- The differences in elastic modulus result in shear stresses at the interface
- The implant design and means of fixation must be able to withstand these shear stresses.
- (3) immediate methods = cement, press-fit, screw (kyon)/threaded(helica)/lateral bolt (BFX)
cementless
immediate fixation:
- For a press-fit implant, compressive forces at the interface must be greater than the shear stresses.
- This compression occurs as the press-fit implant is impacted or subsides into the bone
- Historically, synonymous with press-fit, an interference fit in which the component being placed is slightly larger than the cavity.
- However, current veterinary achieve it by means other than press-fit > locked screw or threaded systems
long term fixation:
- generally rely on bone ingrowth (osseointegration) or bone ongrowth for long-term stability.
- Bone ingrowth > implants that have a porous surface coating where the bone interdigitates with the implant.
- Bone ongrowth > on surfaces with a roughened surface texture where the bone is directly apposed to the implant surface, without an intervening fibrous membrane
- press-fit > if insufficient friction is achieved to counteract shear stresses, then osseointegration will not be achieved
What environment is necessary for bone ingrowth (osseointegration)? (3)
BFX
Pore size 50 - 400mcm
Micromotion less than 20mcm
Porosity (voids:material) of 30-40% is ideal
porosity is achieved using a sintered bead surface