Ch 20 Biopsy princples Flashcards
What the 2 main types of cutting needles for needle-core biopsies?
Tru-Cut needles - Hand powered and automated version
Franklin-silverman needle - split needle design
To waht depth should cutting needled be placed into the tissue?
How should the sample be removed?
At least 1.5cm into tissue of interest
Sample removed with a 25g needle
What are the three main aspiration needle-core biopsy needles?
Menghini
Klatskin
Jamshidi
Menghini has an external bevel whereas Klatskin and Jamshidi have an internal bevel allowing a larger sample with no increased risk
What is a vacuum-assisted needle-core biopsy device?
Similar to Tru-Cut but with the addition of a vacuum
How often to needle-core biopsies get a diagnosis?
How often does thi diagnosis agree with surgically obtained biopsies?
TruCut is diagnostic in 40-97%
Agrees with surgical biopsy in 54-94%
What range of sizes are punch biopsies available?
1-8mm
What is the recommended location when obtaining an incisinal biopsy?
At the junction of mass and normal adjacent tissue
- Must consider spread of disease to uninvolved tissue
- Avoid the periphery in bone lesions as this will most likely sample reactive periosteum
bone: Radiographs can be helpful to identify an appropriate biopsy site
type of laparoscopic biopsy
A - Laparoscopic cup biopsy forceps
B - Laparoscopic punch biopsy forceps
Cup forceps will tear whereas punch forceps will cut
This is a self-ligating loop (SurgiTie)
- A - preformed loop
- B - Knot
- C - Nylon carrier
- D - Scored black band
- E - Proximal end
- F - Optional delivery system for endoscopic surgery
How do pre-sx biopsies compare with post-excision histology in soft tissue sarcomas?
~60% are in agreement
~30% underestimate the grade
12% overestimate the grade
Agreement increased to 87% when classified as low vs high
What are the three options for obtaining lymph node biopsies
Excisional
Guillotine (if full excision risks potential vascular damage)
Laparoscopically with cup forceps
needle-core, punch, and incisional biopsies for STS
Needle-core biopsy techniques may be used to biopsy cutaneous and subcutaneous masses in dogs with accuracy comparable to that of surgical excision histopathology in 96% of cases.
How did sentinel LN mapping alter treatment in dogs with MCT
Altered the treatment plan of 42% of dogs
What is the main concern regarding thyroid biopsies?
Highly vascular - ultrasound guidance necessary, if freely movable consider excisional biopsy
Can you use automated TruCut biopsy deviced in cats?
with CAUTION!!
One study showed mortality 20% due to intense vagotonia - this was also seen at a similar rate with semiautomated devices however there were no deaths in this group