Ch 14 Acid Base Imbalance Flashcards
Normal PaO2
80-100 mmHg
Normal PaCo2
35-45 mmHg
Normal bicarbonate
21-28 mEq/L
Normal Lactate
3-7 mg/dl
What organ controls bicarbonate levels?
Kidneys
Fatal pH levels
less than 6.9 or above 7.8
4 causes of metabolic acidosis
overproduction of H ions (DKA or starvation), anaerobic glucose breakdown (lactic acidosis, seizures, fever) and excessive intake of acids (alcohol, aspirin)
under elimination of H ions- kidney failure causes decreased secretion
underproduction of bicarbonate ions- due to renal , pancreas, or liver failure
over elimination of bicarcbonate ions- due to diarrhea
Lab results of metabolic acidosis
pH ↓ HCo3↓ PaCo2 is normal
Respiratory acidosis
caused by Co2 retention
Causes of respiratory acidosis
Poor gas exchange
pneumonia, TB, emphysema, pulmonary emboli or edema
Lab results of respiratory acidosis
pH↓ HCo3 normal PaCo2 ↑ if acidosis is chronic, HCO3 will be elevated because it is trying to compensate
Manifestations of acidosis
similar to hyperkalemia
lethargy, muscle weakness, hypotension, bradycardia, Kussmauls respirations
Skin manifestations with metabolic acidosis
skin will be warm, flushed and dry
Skin manifestations with respiratory acidosis
skin will be pale or cyanotic and dry
Cause of metabolic alkalosis
an increase of bases (increased intake of oral antacids or massive blood transfusions) or a decrease of acids (prolonged vomiting, excess cortisol, hyperaldosteronism, diuretics, prolonged suctioning)