Cardiovascular Drug Poisoning

Question 1

What’re the clinical features of cardiac drug poisoning?
-Cardiovascular
- Neurological

Answer 1

-Cardio: hypotension, bradycardia, reflex tachycardia, and tachyarrhythmias
-Neuro: Somnolence, unconsciousness, and seizures

Question 2

What is the condition of somnolence?

Answer 2

State of drowsiness which a patient can easily aroused

Question 3

Beta blocker poisoning consists of what clinical symptoms?
-Other features?

Answer 3

Typically bradycardia, hypotension, and CNS depression; aswell as the other CV poisoning symptoms
-Other: Delirium, seizures, Bronchospasm

Question 4

What’re the diagnostic tests to run to depict beta blocker poisoning?
-What results can conclude suspection?

Answer 4

Laboratory studies
-Hypoglycemia and hyperkalemia

Question 5

Management of beta blocker poisoning:
-Initial management (hypotension and sympt. Bradycardia)
-persistent instability after initial management

Answer 5

-initial:
• Hypotension: IV fluid volume
• sympt. Bradycardia: atropine

-Persistent:
High dose glucagon therapy, calcium for drug poisoning. And High dose euglycemic insulin therapy (high dose insulin AND glucose)

Question 6

Digoxin poisoning:
-Risk factors?

Answer 6

Electrolyte imbalances, renal failure, volume depletion, and drug interactions

Question 7

Management of Digoxin poisoning?

Answer 7

Administer digoxin immune fab (Digifab) if indicated, otherwise treat underlying