Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Cardiovascular Diseases > Calcium Channel blockers > Flashcards

Calcium Channel blockers Flashcards

1
Q

What are the two categories of calcium channel blockers?

A

Dihydropyridines and nondihydropyridines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the short acting Dihydropyridine CCBs?

A

Nifedipine, clevidipine, and nimodipine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the intermediate acting dihydropyridine CCBs?

A

Nitrendipine, nicardipine, and lercanidipine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What dihydropyridine CCBs long acting are there?

A

Amlodipine and felodipine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the effects of dihydropyridines?
-any myocardial depressant activity?

A

Potent vasodilator
-minimal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Any side effects of dihydropyridines?

A

Headache, peripheral edema, flushing, reflex tachycardia, gingival hyperplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What’re the general indications of dihydropyridine CCBs?

A

Arterial HTN, angina pectoris, Raynaud phenomenon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Nicardipine and clevidipine are specific to what condition? (Pathology)

A

Hypertensive emergency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Nimodipine is specific to what condition? (Pathology)

A

Subarachnoid hemorrhage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What nondihydropyridine CCB’s are benzothiazepines?

A

Diltiazem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What’re the effects if diltiazem?
-Any myocardial depressant activity?

A

Moderate vasodilator
-Moderate activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What nondihydropyridine are phenylalkylamines?

A

Verapamil and gallopamil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What’re the effects of verapamil and gallopamil?
-Any myocardial depressant activity?

A

Moderate vasodilator
-Potent myocardial depressant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What’re the side effects of nondihydropyridine?

A

Reduced contractility, bradycardia, AV block, gingival hyperplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What side effects are specific to verapamil?

A

Constipation and hyperprolactinemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What’re the indications to prescribe nondihydropyridine CCBs?

A

Arterial HTN, Supraventricular tachyarrhythmias, angina, hypertrophic obstructive cardiomyopathy

17
Q

What’s verapamils other specific indication for prescription besides the main indications of nondihydropyridines?

A

Migraines

18
Q

CCBs bind to and block ____ type calcium channel blockers resulting in _____ frequency of calcium channel opening

A

L type
Decreased

19
Q

What’re the indications for ALL CCB’s

A

Arterial HTN, stable angina, vasospastic angina, and achalasia

20
Q

Why aren’t short acting CCBs not indicated for monotherapy of angina?

A

Because they cause hypotension and secondary reflex tachycardia

21
Q

nondihydropyridine CCBs should not be combined with beta blockers because why?

A

They can enhance the negative inotropic (force of contraction) , chronotropic (heart rate), and dromotropic (conduction) effects of beta blockers

22
Q

Phenylalkylamines are contraindicated in cases of ____________ because of their negative effects on myocardial contractility

A

Heart failure

Cardiovascular Diseases (36 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions