CAD Pharm. Flashcards
Overview:
What are the three agents for secondary prevention?
Antiplatelet agents, ACEI’s, and ARBS
Secondary Prevention:
Anti platelet agents:
-2 agents and doses
- recommended with what patients?
- Aspirin (75-162 mg PO once daily) OR clopidogrel (75mg PO once daily)
- Recommended in all patients with CAD
What ACEI’s are used for CAD?
-Agents used and Doses
Lisinopril (2.5-10 mg PO x1/d, titrate up to 10-40 mg)
Ramipril (2.5-10 mg PO x1/d)
What ARB’s are used for CAD?
- Agents and doses
Losartan (25-100 mg PO x1/d)
Valsartan (20-160 mg PO x2/d)
What is the preferred agent between ACEI’s and ARB’s in CAD patients?
ACEI’s
When are ACEI’s and ARB’s indicated for patients with CAD? (What underlying comorbidities)
HTN, diabetes, LVEF <40%, CKD
Secondary prevention and antianginal treatment of CAD consists of what drug class?
Beta Blockers
What beta blockers are used?
- give dosages
Carvedilol (6.25-25mg PO every 12hrs)
Metoprolol (50-100mg PO every 12hrs, max 400mg/D)
Bisoprolol (2.5-10 mg PO x1/d, max 20mg/D)
Beta blockers are considered for patients with?
- also considered first line _____ therapy
Stable angina, CAD, HTN
- Antihypertensive
What are the three drug classes used for antianginal treatment of CAD?
CCB’s, nitrates, and metabolic modulators
What are two types of CCB’s?
Dihydropyridines and Non-dihydropyridines
What dihydropyridines are used for CAD?
- Add doses
Amlodipine: 5-10 mg PO 1/D
Nifedipine: 30-90 mg PO 1/D
What are the Non-dihydropyridines used for CAD?
- Add doses
Verapamil: 40-120mg PO every 8 hrs
Diltiazem: 120-480 mg PO 1/D
Which CCB’s are preferred in patients with conduction defects?
Dihydropyridines
If your patient with CAD is on CCB’s and symptoms persist, what other drug class should they be combined with?
Beta Blockers
