Cardiac Glycosides Flashcards
1
Q
What is the pharmacodynamics of cardiac glycosides?
A
It inhibition of sodium potassium ATPase causing higher intracellular calcium concentration
2
Q
What is the MOA of cardiac glycosides
A
Increase contractility, reduced velocity of electric conduction and reduction of heart rate
3
Q
In cardiac glycosides poisoning, medications consist of ________ and its derivatives
A
Digoxin
4
Q
What plants contain natural occurring cardiac glycosides?
A
Foxglove and lily of the valley
5
Q
What’re the indications of cardiac glycosides?
A
CHF
Afib
SVT
6
Q
What’re the interactions of cardiac glycosides?
A
Potassium depleting diuretics
Verapamil, diltiazem, amiodarone, quinidine
