Cardiovascular Flashcards
Functions of the cardiovascular system
Transport
Protection
Regulation
Composition of blood
55% plasma
1% Buffy coat
45% erythrocytes
Blood plasma proteins
Fibrinogen
Albumin
Globulins
Blood non proteins
Water 92%
Electrolytes
Glucose
Waste
Hormones
Dissolved gas
Fibrinogen
Sticky
Helps clot
Albumin
Most abundant
Influences blood pressure and flow
Transports blood solutes
Maintains ph
Globulins
Alpha & Beta- transport
Gamma- antibodies
Erythrocyte (red blood cells) form
Concave and discoid
No dna, mitochondria, or nucleus
Most abundant formed element
Erythrocytes function
Transport oxygen and carbon dioxide
Hemoglobin
4 protein chains of globin
- each carries a CO2 molecule
4 heme groups
- each carries an oxygen molecule
Erythrocyte life cycle
120 days
Broken down by liver and spleen
Leukocytes (white blood cells)
Least abundant
Immunity
Types of leukocytes
Granulocytes
Arganulocytes
Three types of granulocytes
Neutrophils
Eosinophils
Basophils
Neutrophils (granulocytes)
Most abundant
Fight bacteria
Eosinophils (granulocytes)
Seasonal
Fight allergens parasites and worms
Basophils (granulocytes)
Rarest
Release histamine
Release anti clogging molecule
Help heal damaged tissue
Types of argranulocytes
Lymphocytes
Monocytes
Lymphocytes (argranulocytes)
Smallest and most abundant
Destroy cancer cells, foreign cells, and viruses
Immune memory
Secrete antibodies
Coordination
Monocytes (argranulocytes)
Largest WBC
Pathogens and debris
Platelets (thrombocytes)
No nucleus
Small
Primary function- hemostasis
Three layers of blood vessels
Tunica interns
Tunica media
Tunica externa
Tunica interna
Simple squamous endothelium
Semi-permeable
Tunica media
Smooth muscle
Vasodilation/constriction
Thickest layer
Tunica externa
Loose connective tissue
Protection and anchors to surrounding tissue
Types of blood vessels
Arteries
Capillaries
Veins
Arteries
Carry blood away from the heart
- conducting
- distributing
- arterioles
Conducting arteries
Largest
Ex. Aorta and pulmonary trunk
Distributing arteries
Middle size
Ex. Circumflex artery and left pulmonary artery
Arterioles
Smallest
Supply local regions
Capillaries
Smallest blood vessels
Form bed btw arterioles and venules
Highly permeable
Only tunica interna (endothelium)
Veins
Carry blood to the heart
- venules
- Medium veins
- large veins
Venules
Smallest
Drain blood from capillary bed
Start journey back to heart
Medium veins
Form when venules merge
Some contain valves
Large veins
Form when medium veins merge
Ex. Inferior vena cava and pulmonary veins
Mechanisms of venous return
Pressure gradient- created by heart
Gravity
Skeletal muscle pump
Blood pressure
Force exerted by the blood on the inner walls of the vessels
Higher in arteries, lower in veins
Systolic pressure
When the heart contracts
Highest pressure
Diastolic pressure
When the heart rests
Lowest pressure
Cardiovascular divisions
Pulmonary
Systemic
Pulmonary
The route blood take from the right side of the heart to the lungs and back
Systemic
The route blood takes from the left side of the heart to the tissues of the body and back to the right side of the heart
Pericardium
Heart covering
Three layers
- parietal
- visceral
- pericardial cavity
Parietal pericardium
Outer layer
Visceral pericardium
Inner layer
Pericardial cavity
Space btw parietal and visceral pericardium
Filled with fluid
Heart wall layers
Epicardium
Myocardium
Endocardium
Epicardium
Outer layer of the heart
Thin
Made of epithelium and Areolar tissue
Myocardium
Middle layer
Thick
Made of cardiac muscle
Does the contracting
Endocardium
Inner layer
Similar to epicardium
Lines heart chambers
Chambers
Atria
Ventricles
Atria
Upper chambers
Separated by interatrial septum
Right atrium
Receives deoxygenated blood and delivers it to the right ventricle
Left atrium
Receives oxygenated blood from the lungs and delivers it to the left ventricle
Ventricles
Lower chambers
Separates by the interventricular septum
Right ventricle
Receives deoxygenated blood from the right atria and sends it to the lungs
Left ventricle
Receives oxygenated blood from the left atria and sends it to the body
Heart valves
Four
2 Atrioventricular
2 Semilunar
Atrioventricular valves
Btw atria and ventricles
Tendons cords prevent relapse of the cord
Semilunar valves
Btw ventricles and exciting blood vessels
Cardiac muscle cells
(Cardiocytes)
Intercalated disks
Abundant mitochondria
Contain actin & myosin
Striated, involuntary, branched
The conduction system
Specialized cardiocytes that can generate electrical signals on their own
Sinoatrial node (SA)
“Pacemaker”
Upper right corner of the right atrium
Initiate the action potential for the stimulation of the other cardiocytes
Atrioventricular node (AV)
Lower left of the right atrium
Responds to signal from SA node
Sends signal toward the ventricles
Atrioventricular bundle and branches
Nerve like collection
Comes off of the AV node and moves into interventricular septum
Signal is delayed to allow blood filling
Purkinje fibers
Off of the atrioventricular branches and extend up the walls of the ventricles
Finally distribute the delayed AB nodes signal
Electrocariogram
Graphs the activity of the heart
P wave
When the SA node sends a signal throughout the atria causing them to polarize and contract
QRS wave
When the AV node sends a signal throughout the ventricles causing them to polarize and contract
Depolarization of the atria
T wave
Depolarization and relaxation of the ventricles