Body Systems L11 Notes Flashcards
What are the functions of the cardiovascular system?
Maintain adaptable supply of blood -> tissues.
» Supply nutrients & signalling molecules
»Remove waste products
Establish pressure differentials across tissues -> capillary exchange.
What are the two factors which determine blood flow?
Blood flow determined:
- Resistance -> R
- Pressure difference -> P
What is the equation representing blood flow?
F = ▲P / ▲R
What is vascular resistance determined by?
Determined by: ->> L = length of vessel ->> r = radius of vessel ->> ꞃ = fluid viscosity >>(protein conc.)
What determines the fluid viscosity of blood?
-» ꞃ = fluid viscosity
|»_space;(protein conc.)
What is the equation for calculation of vascular resistance?
R = (8Lꞃ) / (πr4)
What is the equation for calculation of blood flow using pressure & viscosity?
F = ▲P((πr4) / (8Lꞃ))
What are the two equations for calculation of blood flow & what values do both equations require?
F = ▲P / ▲R
Pressure difference & resistance difference
F = ▲P((πr4) / (8Lꞃ))
Pressure difference, radius, length & fluid viscosity.
What does the Poiseuille-Hagen Eqn state?
Poiseuille-Hagen Eqn:
Flow -> proportional -> r4
Small changes in arteriole diameter
»_space;Drastically alter tissue blood flow
Rate of flow -> blood through vessels
-» Proportional -> Vessel diameter
What causes cardiovascular pressure gradient formation?
Contraction -> Heart muscles -> Generates CVS pressure gradient.
State the intra-cardiac pressures of each component of heart during systole & diastole.
Left Ventricle: Contraction (systole) -> 100-140mmHg Relaxation (diastole) -> 3-12mmHg Left Atrium: Contraction (systole) -> 6-12mmHg Right Ventricle: Contraction (systole) -> 15-30mmHg Relaxation (diastole) -> 3-8mmHg Right Atrial: Contraction (systole) -> 2-6mmHg
State the intra-cardiac pressures of the left ventricle of heart during systole & diastole.
Left Ventricle:
Contraction (systole) -> 100-140mmHg
Relaxation (diastole) -> 3-12mmHg
State the intra-cardiac pressures of the right ventricle of heart during systole & diastole.
Right Ventricle:
Contraction (systole) -> 15-30mmHg
Relaxation (diastole) -> 3-8mmHg
State the intra-cardiac pressures of the left atrium of heart during systole.
Left Atrium:
Contraction (systole) -> 6-12mmHg
State the intra-cardiac pressures of the right atrium of heart during systole.
Right Atrial:
Contraction (systole) -> 2-6mmHg
State the intra-cardiac pressures of the right ventricle of heart during systole
Contraction (systole) -> 15-30mmHg
State the intra-cardiac pressures of the left ventricle of heart during systole
Contraction (systole) -> 100-140mmHg
State the intra-cardiac pressures of the right ventricle of heart during diastole.
Relaxation (diastole) -> 3-8mmHg
State the intra-cardiac pressures of the left ventricle of heart during diastole.
Relaxation (diastole) -> 3-12mmHg
What is classed as a high blood pressure gradient in systole & diastole?
High:
Systolic: >140mmHg
Diastolic: >90mmHg
What is classed as a high blood pressure gradient in systole?
Systolic: >140mmHg