blood glucose concentration regulation Flashcards

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1
Q

what importance does the liver play

A

plays a role in maintaining the blood glucose concentration levels as this is where the enzyme action take place

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2
Q

what is glycogenesis

A

when the blood glucose concentration is too high liver takes glucose which is converted into glycogen

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3
Q

what is glycogenolysis

A

when the glucose concentraion in the blood is too low liver converts glycogen into glucose which then diffuses into the blood

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4
Q

what is gluconogenesis

A

conversion of amino acids and glycerol into glucose when glycogen levels are low

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5
Q

why is glucose levels need to be maintained

A

substrate for respiration providing energy for all organism and production of atp

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6
Q

what would happen if there was little to no glucose

A

cell will not respire have no energy and then die

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7
Q

why is brain cells most sensitive

A

as they only respire with glucose

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8
Q

What will happen if the glucose level is too high

A

it will decrease the osomotic balance and decrease the water potential in the blood leading to dehydration

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9
Q

what is the islet of langherns give the differences

A

hormone producing cells that produce both alpha bigger and release glucagon and beta cells release insulin

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10
Q

where does blood glucose come from

A

directly from the diet in the form of carbs and starch hydrolyzing
hydrolysis of glycogen in the liver
from gluconegenesis

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11
Q

what happens when the concentration rises

A

the b cells have receptors that detect stimulus rise in blood sugar and respond by secreting insulin directly into the blood

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12
Q

what is insulin

A

a globur protien made from 51 amino acids

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13
Q

what does the insulin do

A

bind to glycoprotein receptors that are found in every cells
changing the tertiary structure of the glucose transport carrier protein so that they open and glucose taken into the cell by facillitated diffusion
also activate enzyme that convert gluvos to glycogen

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14
Q

how are these protiens present at. low concentration

A

they are found in vescicles that then fuse with the membrane when the concentration is high

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15
Q

what role does the liver play in regulating glucose concentration levels

A

the conversion of glucose to glycogen only takes place in the liver so can store it in is mass and glycogenelysis only takes place in the liver

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16
Q

what happens if the level of glucose is too high

A

the alpha cells detect the rise in glucose concentration and then secrete glucagon directly into the blood plasma

17
Q

what response does glucagon produce

A

attach to specific protein receptors on liver and muscle cell membrane activating enzymes that convert glycogen into glucose
also activate enzyme that convert amino acids and glycerol into glucose

18
Q

how does the insulin reduce the concentration what does it dp to the body

A

increase rate of absorption
increasing respiratory rate which then uses glucose more easily
increasing rate of conversion of glucose to fat and glycogen

19
Q

what role does adrenaline play in maintaining glucose concentration

A

sympathetic response when adrenaline is released it binds to specific proteins on the liver cells which activate enzymes that convert glycogen to glucose

20
Q

why does adrenaline do this

A

so there is more glucose available for respiration

21
Q

what are hormones

A

chemical messengers secreted by gland and bind to specific receptor at target cell or organ

22
Q

what is the secondry messenger model

A

two hormones involved in the regulation of blood glucose level

23
Q

what is the mechanism involve

A

adrenaline binds to a transmembrane protein within the membrane of the liver cell
the binding causes the protein to change shape
change of protein leads to the activation of adenyl cyclase to convert atp to camp
camp then acts as a second messenger and binds to protein kinase and changing its shape and activating it to catalyse glycogen to glucose