Blood (FINAL) Flashcards
What is the general role of blood?

Blood is a transport agent
What type of things does blood transport around the body?

- Gases (O2, CO2)
- Nutrients
- Hormones
- Waste
What are the four components that make up blood?

- Plasma
- Leukocytes (WBC’s)
- Erythrocytes (RBC’s)
- Platelets
Which of the componets of blood are made in the bone marrow?

- Leukocytes (WBC’s)
- Erythrocytes (RBC’s)
- Platelets
What are hemocytoblasts?

Blood cell maker (stem cell)
Which of the component(s) of the blood does diet aid in its formation?

Erythrocytes (RBC’s)
Needs iron (Fe2+)
What is the function of plasma?

Plasma is a liquid that transports:
- Hormonnes
- Glucose
- Wastes
- Everything els
What organ(s) detects O2 in the body?

- Liver
- Kidney
When there is too much O2 in the body what increases in order for the number of RBCs to decrease?

Decrease in EPO (Erythropoietin) = Decrease in RBCs
When there is too little O2 in the body what increases in order for the number of RBCs to increase?

Increase in EPO (Erythropoietin) = Increase in RBCs
What is the general function of leukocytes (WBCs)?

Immunity
What is the general purpose of erythrocytes (RBCs)?

Carries O2
What is the general function of platelets?

Clotting
What are the 8 steps of processing old RBCs?

- Old RBCs last 6 weeks
- Sent to the liver
- The liver takes the hemoglobin out of the old RBCs
- The iron from the hemoglobin is sent to the bone marrow
- Everything else except the hemoglobin is turned into bilirubin
- Bilirubin is turned into bile
- The bile is sent through the small intestines
- Eventually takes it to the toilet (waste)
How long do RBCs last?

~6 weeks
What organ does old RBCs get sent to?

The liver
What does the liver do to the old RBC’s

Takes the hemoglobin (Fe carring protein) out of the old RBCs
Where is the Fe2+ (iron) sent to after the liver is done processing the hemoglobin?

To the bone marrow
What does the liver turn “everything else” that is not hemoglobin from the old RBCs?

To bilirubin
What is bilirubin?
(Besides the name Dr. Lector gave the senator of Buffola Bill)

The waste product of the breaking down of old RBC in the liver
Which organ produces bilirubin?

Liver
What condition is the result of excess bilirubin in the body?

Jaundice
After the liver has turned parts of the old RBCs into bilirubin, it is then turned into what?

Bile
Bile goes through what organ to be eventually expelled in the toilet as waste?

Small intestines
What type of blood can a patient get with type A?

Type A & O
What type of blood can a patient get with type AB?

Types A, B, AB, & O
What type of blood can a patient get with type B?

Type B & O
What type of blood can a patient get with type O?

Type O
Which blood type is a universal donor?

Type O
Which blood type is the universal recipient?

Type AB
A blood donor has type A blood, who can the donor give blood to?

Recipients with blood types:
- A
- AB
A blood donor has type B blood, who can the donor give blood to?
Recipients with blood types:
- B
- AB
A blood donor has type AB blood, who can the donor give blood to?

Recipients with blood types:
- AB
A blood donor has type O blood, who can the donor give blood to?

Repicients with blood types:
- A
- AB
- B
- O
What is agglutination?

When you mix different blood types together resulting in the RBCs clumping together (part of an immune response) like cottage cheese
What does it mean when blood is Rh+?

The RBC has the Rh antigen
at does it mean when blood is Rh-?

The RBC does NOT have the Rh antigen
What is an antibody?

Immune cells
If a patient with blood type A+ needs a blood transfusion, who can be the donor?

Blood types donors are:
- A+
- A-
- O+
- O-
If a patient with blood type A- needs a blood transfusion, who can be the donor?

Blood type donors:
- A-
- O-
If a patient with blood type AB+ needs a blood transfusion, who can be the donor?

Blood type donors:
- A+
- A-
- AB+
- AB-
- B+
- B-
- O+
- O-
If a patient with blood type AB- needs a blood transfusion, who can be the donor?

Blood type donors:
- A-
- B-
- AB-
- O-
If a patient with blood type B+ needs a blood transfusion, who can be the donor?

Blood type donors:
- B+
- B-
- O+
- O-
If a patient with blood type B+ needs a blood transfusion, who can be the donor?

Blood type donors:
- B+
- B-
- O+
- O-
If a patient with blood type B- needs a blood transfusion, who can be the donor?

Blood type donors:
- B-
- O-
If a patient with blood type O+ needs a blood transfusion, who can be the donor?

Blood type donors:
- O+
- O-
If a patient with blood type O- needs a blood transfusion, who can be the donor?

Blood type donors:
- O-
What blood type with Rh group is the universal donor?

Type O-
What blood type with Rh group is the universal recipient?

Type AB+
A person with type A+ blood wants to donate blood. Who can be the recipients of their blood?

Recipients with blood types:
- A+
- AB+
A person with type A- blood wants to donate blood. Who can be the recipients of their blood?

Recipients with blood types:
- A-
- AB+
- AB-
A person with type AB+ blood wants to donate blood. Who can be the recipients of their blood?

Recipients with blood type:
- AB+
A person with type AB- blood wants to donate blood. Who can be the recipients of their blood?

Recipients with blood types:
- AB+
- AB-
A person with type B+ blood wants to donate blood. Who can be the recipients of their blood?

Recipients with blood types:
- B+
- AB+
A person with type AB- blood wants to donate blood. Who can be the recipients of their blood?

Recipients with blood types:
- AB+
- AB-
A person with type O+ blood wants to donate blood. Who can be the recipients of their blood?

Recipients with blood types:
- A+
- AB+
- B+
- O+
A person with type O- blood wants to donate blood. Who can be the recipients of their blood?

Recipients with blood types:
- A+
- A-
- AB+
- AB-
- B+
- B-
- O+
- O-
The process of blood clotting is an example of negative or postive feedback?

Positve feedback
As clotting gets under way, each step releases chemicals that accelerate the process. This escalating process is a positive feedbackloop that ends with the formation of a blood clot, which patches the vessel wall and stops the bleeding.
What are the first three steps in blood clotting after you cut yourself?

- The blood vessel spasms to become smaller
- Platelets plug to cork the wound
- The blood clotting process
What is the purpose of the blood vessel spasming in the blood clotting process?

To make the blood vessel smaller thus causing less blood flow
The platelet plug causes the formation of what?

A scab
The blood clotting pathways consists of what two different routes (pathways)?

- Intrinsic Pathway
- Extrinsic Pathway
What is the location in the blood clotting process for the intrinsic pathway?

Intrinsic = within the blood vessels
What is the location in the blood clotting process for the extrinsic pathway?

Extrinsic = tissue damage (outside of the blood vessel)
What is the order of clotthing factors for the intrinsic pathway?

Factor XII→Factor XI→Factor IX (with Factor VIII) →Factor X
What is the order of clotthing factors for the extrinsic pathway?

Tissue Factor (TF) III → (with Factor VII) ⇒ Factor X
Which blood clotting factor begins the common pathway?

Factor X
Which clotting factor begins the intrinsic pathway?

Factor XII
Which clotting factor begins the extrinsic pathway?

Tissue Factor (TF) III
Tissue Factor III with what other factor begins the common pathway for what pathway?

Tissue factor (TF) III pairs with Factor VII in the extrinsic pathway
Factor XII turns on what bloot clotting factor? Which pathway?

Factor XI
Intrinsic pathway
Factor XI turns on what bloot clotting factor? Which pathway?

Factor IX
Intrinsic pathway
What two blood clotting factors in the instrinsic pathway turn on the common pathway?

- Factor IX
- Factor VIII
The intrinsic and extrinsic pathways have what in common?

Both end in Factor X and have the common pathway
What is the starting factor in the common pathway?

Factor X
Factor X pairs up with what factor to turn on Factor II?

Factor V
What is another name for thrombin?

Factor V
What is another name for Factor V?

Thrombin
Factor II leads to what factor of what pathway?

Factor I (Fibrin)
Common pathway
What is another name for Factor I of what pathway?

Fibrin
Common pathway
What is another name of Fibrin of what pathway?

Factor I
Common pathway
Factor I leads to the final step which is the formation of what?

A clot