Block 56: Lung Flashcards

1
Q

Bronchiectasis

A

bronchial thickening and dilation to due to a recurrent cycle of bacterial infection, inflammation and tissue damage

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2
Q

In young patient, most common underlying etiology for bronchiectasis is

A

cystic fibrosis

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3
Q

where in the lung is bronchiectasis due to cystic fibrosis located

A

upper lung lobe

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4
Q

common side effect of systemic glucocorticoids seen in labs

A

leukocytosis with neutrophilic predominance

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5
Q

what lab value is expected for hypersensitivity reaction

A

eosinophilia

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6
Q

MOA of ACE

A

metabolism of kinins and substanceP

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7
Q

destruction and permanent damage of the conducting airway occurs in

A

bronchiectasis

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8
Q

pt with COPD and acute-onset shortness of breath, hypoxia and unilaterally decreased breath sounds likely has? most common cause?

A

secondary spontaneous pneumothorax

- alveolar blebs

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9
Q

risk factors for obstructive atelectasis

A
  • foreign body aspiration
  • malignancy
  • severe pneumonia ( mucus plug)
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10
Q

pts develop what after a fat embolsm

A
  • respiratory distress
  • neurological abnormalities
  • petechial rash
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11
Q

acute dyspnea and hypoxia after motor vehicle collision likely has what

A

pulmonary contusion

- he was prone to blunt thoracic trauma

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12
Q

clinical feature of pulmonary contusion

A

intra-alveolar hemorrhage and edema

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13
Q

some clinical features to look for in pulmonary embolism

A
  • pleuritic chest pain
  • tachypnea
  • atrial fibrillation
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14
Q

triad for cardiac tamponade

A
  • distant heart sounds
  • hypotension
  • jugular venous distension
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15
Q

pleuritic chest pain

A

pain when you breathe, cough and sneeze

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16
Q

Peak airway pressure equation

A

Airway resistance + plateau pressure

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17
Q

plateau pressure equation

A

elastic pressure + positive end-expiratory pressure (PEEP)

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18
Q

How is PEEP calculated

A

end-expiratory hold maneuver

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19
Q

lung compliance

A

ability to expand

20
Q

how does pneumonia cause hypoxemia

A

right-to-left intrapulmonary shunting

V/Q mismatch

21
Q

how is theophylline meabolized

A

cytochrome oxidase in liver

22
Q

antibiotic known to decrease theophylline clearance

A

ciprofloxacin

23
Q

patient with acute presentation of dyspnea, chest pain, tachycardia, hypoxia, and clear lung sounds has

A

PE

24
Q

most common cause of community-acquired pneumonia

A

strept. pneumoniae

25
Q

on the vent, what influences O2? which one are you more likely to reduce to decrease O2

A

FiO2 (this one) and PEEP

26
Q

on vent what, influences CO2

A

RR and TV

27
Q

what tumor produced both alpha fetoprotein and human chorionic gonadotropin tumor marker

A

Nonseminomatous germ cell tumors

28
Q

3 most common causes of chronic cough a

A
  1. postnasal drip
  2. asthma
  3. GERD
29
Q

MOA of Chlorpheniramine

A

H1 Antihistamine receptor blocker

30
Q

asthma patient that has sore throat, morning hoarsness, worsening cough only at night, and increased need for her albuteral inhaler following meals also has what

A

GERD

31
Q

when are antibiotics given in COPD patient

A
  • moderate to severe exacerbation of COPD

- pts needing mechanical ventilation

32
Q

what causes clubbing

A

magakaryotcytes are not broken down in lungs, and then get stuck in fingers
- hypoxia does not cause clubbing

33
Q

what does CT show for pulmonary embolism

A

wedge-shaped infarction

34
Q

development of clubbing and sudden-onset joint artropathy in chronic smoker suggests? what can cause this

A

hypertrophic osteoarthropathy

- any lung cancer

35
Q

Name 2 ways you can increase oxygenation on a vent? which one would you increase in ARDS patient and why?

A

FiO2 and PEEP

- PEEP: prevent alveolar collapse during respiratory cycles and my also reopen some alveoli

36
Q

If high levels (greater than 60%) of FiO2 is required to maintain oxygen, how do you increase the amount of oxygen a patient gets on the vent

A

PEEP

37
Q

Aspirin-exacerbated respiratory disease is most often seen in patient with a history of

A

asthma or chronic rhino-sinusitis with nasal polyposis

38
Q

clinical symptoms of aspirin-exacerbated respiratory disease

A

bronchospasm
nasal congestion
following aspirin ingeston

39
Q

what type of reaction is aspirin-exacerbated respiratory disease

A

non-IgE mediated

psuedoallergic drug reaction

40
Q

where are bronchogenic cysts located

A

middle mediastinum

41
Q

where are thymoma’s found

A

anterior mediastinum

42
Q

where are all neurogenic tumors located in the mediastinum

A

posterior mediastinum

43
Q

PE for lung consolidation

A

dullness to percussion
increased intensity of breath sounds
increased tactile fremitus

44
Q

percent predicted obstructive pattern FEV1/FVC

A

less than 70%

45
Q

predicted restrictive pattern FEV1/FEV

A

greater than 70%

46
Q

what organs are involved in granulomatosis with polyangiitis

A
  • upper and lower respiratory tract infection
  • renal involvement
  • glomerulonephritis