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Sketchy Medical > Autonomic Sympathetic Drugs: Beta Blockers > Flashcards

Autonomic Sympathetic Drugs: Beta Blockers Flashcards

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USMLE® Step 1 flashcards
1
Q

Beta blockers are

A

beta adrenergic receptor antagonists

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2
Q

_________ suffix of beta blockers

A

“-lol”

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3
Q

Beta blockers include

A
  1. Propranolol
  2. Metoprolol
  3. Atenolol
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4
Q

Beta blockers decrease

A

beta blockers decrease cardiac contractility (by antagonizing beta-1 receptors in the myocardium)

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5
Q

Beta blockers suppress

A

beta blockers suppress activity at the SA and AV nodes (by antagonizing beta-1 receptors)

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6
Q

Inhibition of SA node activity by beta blockers can cause

A

bradycardia

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7
Q

beta blockers can cause or exacerbate

A

heart block (due to excessive suppression of AV node conduction)

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8
Q

beta blockers are useful in the management of

A

chronic stable angina

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9
Q

beta blockers treat angina by

A

reducing myocardial oxygen demand (decreased heart rate and contractility)

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10
Q

beta-1 selective antagonists

A
  1. Atenolol
  2. Betaxolol
  3. Esmolol
  4. Acebutolol
  5. Metoprolol
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11
Q

the beta-1 selective antagonists primarily suppress

A

the beta-1 selective antagonists primarily suppress adrenergic stimulation of the heart (cardioselective)

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12
Q

cardioselective beta blockers are useful in the

A
  1. acute treatment of MI and other acute coronary syndromes (ACS)
  2. management of chronic heart failure
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13
Q

carvedilol (in addition to cardioselective beta blockers) is useful in the management of

A

chronic heart failure

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14
Q

carvedilol is

A

a nonselective beta blocker and alpha-1 blocker

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15
Q

beta blockers (e.g. carvedilol and cardioselective agents) reduce

A

beta blockers (e.g. carvedilol and cardioselective agents) reduce mortality in chronic heart failure and post-MI

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16
Q

beta blockers reduce cardiac remodeling by

A

beta blockers reduce cardiac remodeling by protecting the heart from excess circulating catecholamines

17
Q

beta blockers are useful in the treatment of

A

hypertension (especially in patients with heart failure or post-MI)

18
Q

beta blockers inhibit

A

beta blockers inhibit production of renin (antagonize beta-1 receptors at the JGA)

19
Q

labetalol is a

A

nonselective beta blocker and alpha-1 blocker

20
Q

labetalol antagonizes

A

alpha-1 receptors causing vasodilation

21
Q

labetalol treats

A

hypertension in pregnancy

22
Q

labetalol is useful in hypertensive emergency due to

A

combined alpha and beta blocking effects

23
Q

IV beta blockers are

A
  1. Labetalol
  2. Esmolol
  3. Propanolol
24
Q

IV beta blockers

A
  1. treat hypertensive emergency
  2. acute management of aortic dissection
  3. management of hypertrophic obstructive cardiomyopathy
25
Q

beta blockers can be used for

A

migraine prophylaxis

26
Q

beta blockers are useful for

A

beta blockers are useful for the symptomatic treatment of thyroid storm (blocks increased sympathetic activity)

27
Q

beta blockers treat

A

essential tremor

28
Q

beta blockers have

A

antiarrhythmic properties

29
Q

nonselective beta blockers can exacerbate

A

asthma and COPD (antagonize beta-2 mediated bronchodilation)

30
Q

topical nonselective beta blockers include

A

timolol

31
Q

topical nonselective beta blockers

A

glaucoma (antagonize beta-2 receptors on the ciliary epithelium → decreased aqueous humor production)

32
Q

beta blockers can cause ______ in men

A

impotence

33
Q

acebutolol

A

a selective beta-1 antagonist with partial agonist activity

34
Q

pindolol

A

a nonselective beta blocker with partial agonist activity

35
Q

beta blockers with partial agonist activity

A

beta blockers with partial agonist activity (e.g. pindolol, acebutolol) should be avoided in patients with heart failure or a history of MI

36
Q

Glucagon treats

A

beta blocker toxicity (stimulates heart via glucagon receptors)

Sketchy Medical (46 decks)

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