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Infectious Disease > Antivirals: Ganciclovir > Flashcards

Antivirals: Ganciclovir Flashcards

1
Q

What is the mechanism of ganciclovir?

A

Nucleoside analogue of guanosine. Phosphorylated by CMV viral protein kinase.

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2
Q

what are examples of ganciclovir?

A

Ganciclovir (IV); valganciclovir (PO)

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3
Q

what is the activity of ganciclovir?

A

Cytomegalovirus (CMV)

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4
Q

what is the adverse effects of ganciclovir?

A
  • Bone marrow suppression –monitor FBC x2/week

- Renal insufficiency –monitor renal panel weekly

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Infectious Disease (55 decks)

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