Antifungals: Echinocandin Flashcards

1
Q

What is the mechanism of echinocandin?

A

Inhibit fungal cell wall synthesis via inhibition of β1,3 D-glucan synthase

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2
Q

What are the examples of echinocandin?

A

Caspofungin; anidulafungin; micafungin

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3
Q

What is the spectrum of activity of echinocandin?

A
  • Candida spp, Aspergillus spp.

- NOT Cryptococcus Spp.

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4
Q

What are the adverse effects of echinocandin?

A

Hepatotoxicity

Injection site reactions

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