Antifungals: Echinocandin Flashcards
1
Q
What is the mechanism of echinocandin?
A
Inhibit fungal cell wall synthesis via inhibition of β1,3 D-glucan synthase
2
Q
What are the examples of echinocandin?
A
Caspofungin; anidulafungin; micafungin
3
Q
What is the spectrum of activity of echinocandin?
A
- Candida spp, Aspergillus spp.
- NOT Cryptococcus Spp.
4
Q
What are the adverse effects of echinocandin?
A
Hepatotoxicity
Injection site reactions