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Farma > Antimigrañosos > Flashcards

Antimigrañosos Flashcards

1
Q

Triptanos (7)

A

Almotriptán, Eletriptán, Flavotriptán, Naratriptán, Rizatriptán, Sumatriptán, Zolmitriptán

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2
Q

Derivados del cornezuelo (3)

A

Ergotamina, Dihidroergotamina, Metisergida

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3
Q

AINEs antimigrañosos (3)

A

Ketorolaco, Ibuprofeno, Ác. acetilsalicílico

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4
Q

Otros antimigrañosos (2)

A

Ketanserina, Flunarizina

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5
Q

MA ergotamina

A

Actúa en receptores 5HT (1b, 1d y alfa-1)

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6
Q

Se da con cafeína para aumentar la biodisponibilidad oral, útil en migraña con o sin aura y hemorragias postparto

A

Ergotamina

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7
Q

EA de ergotamina

A

Ergatismo (necrosis de dedos con HTA y alucinaciones). Causa dependencia física

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8
Q

MA dihidroergotamina

A

Agonista 5HT (1d)

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9
Q

Efectos dihidroergotamina

A

No produce tanta dependencia física, indicaciones iguales que ergotamina

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10
Q

MA metisergida

A

Antagonista 5HT (2a y 2c)

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11
Q

Efectos metisergida

A

Oxitócica y vasoconstrictor

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12
Q

Profilaxis de migraña, Sd de Horton y Sd carcinoide

A

Metisergida

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13
Q

Tx de AINEs

A

Sintomático no específica de ataques de migraña

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14
Q

Tx flunarizina

A

Profilaxis de migraña para ataques severos que no responden a otro medicamento

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15
Q

MA flunarizina

A

Bloquea canales de Ca++

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16
Q

Efectos ketanserina

A

Inhibe agregación plaquetaria

17
Q

Degradados por MAO y CYP3A4
EA vasoespasmo coronario, isquemia y arritmia
CI HTA no controlada, antecedentes de EVC
Tx se da con IMAO

A

Triptanos

18
Q

Tx ataques agudos de migraña. Receptores 5HT 1b y 1d

NO USAR ergos u otro triptano simultáneamente porque pueden causar síndrome serotoninérgico

A

Triptanos

19
Q

SUBCUTÁNEA. Oral y nasal causan cacogeusia

A

Sumatriptán

20
Q

Metabolito N-desmetilado activo tiene más afinidad por el receptor

A

Zolmitriptán

21
Q

2o con acción más prolongada

A

Naratriptán

22
Q

CI relativa en nefrópatas y hepatópatas

A

Rizatriptán

23
Q

CI en hepatópatas

A

Eletriptán

24
Q

El de acción más prolongada

A

Frovatriptán

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