ANS lecture Flashcards
Which cells are adrenergic and what do they release?
release NE
most sympathetic postganglionic neurons
what does the aorticorenal ganglion innervate?
kidney and ureter
what does the inferior mesenteric ganglion innervate?
descending colon, kidneys, sex organs
Define the preganglionic neuron
cell body in the CNS extends from CNS to autonomic ganglion myelinated axon type B fiber small diameter
where are chromaffin cells located and what do they release?
the adrenal medulla and epinephrine and NE
what do the superior cervical ganglia innervate?
pineal gland, eye, lacrimal mucous membrane of the nose and palate, parotid gland, heart, and sublingal and submandibular glands
what are the sensory receptors of the ANS?
mostly interceptors (visceral sensory neurons), some somatic senses and special senses
what does the vagus nerve innervate?
heart, lungs, liver, gall bladder, stomach, pancreas, intestines
What are the ganglia in the neck?
superior, middle, and inferior cervical ganglia
major locations of A1 receptors
smooth muscle fibers in blood vessels, salivary gland cells, and sweat gland cells in thick skin
what organs control the motor output for the ANS?
involuntary control from hypothalamus, limbic system, brainstem, and spinal cord. Limited control from cerebral cortex
What effectors does the autonomic nervous system work on?
smooth muscle, glands, and cardiac muscle
what is the distribution of the parasympathetic division?
limited mainly to head and viscera of thorax, abdomen, and pelvis, some blood vessels
what is dual innervation?
organs receive impulses from both the sympathetic and parasympathetic neurons
What are the four ways axons of sympathetic preganglionic neurons can connect with postganglionic neurons?
- axon can synapse with a postganglionic neuron in the ganglion it first reaches
- an axon may ascend or descend to a higher or lower ganglion
- an axon can continue directly through the trunk to end at a prevertebral ganglion
- an axon can extend to chromaffin cells of the adrenal medulla
What does SLUDD stand for in relation to parasympathetic responses?
salivation lacrimation (tears) urination digestion defacation
what does the celiac ganglion innervate?
liver, gall bladder, bile ducts, stomach, spleen, and pancreas
How many post neurons does a parasympathetic pre neuron usually synapse with and how does that affect function?
only 4-5 all of which supply a single visceral effector, which allows parasympathetic responses to be localized to a single effector
What pattern of projection defines the sympathetic nervous system, and how does it affect function?
divergence which is why many sympathetic responses affect almost the entire body simultaneously.
what are autonomic plexuses?
tangled networks of symp and parasymp axons that lie along major arteries
How many motor neurons do (most) autonomic motor pathways have?
2, in a series one after another
What are the two divisions of the ANS?
sympathetic and parasympathetic
what is an agonist in terms of receptors?
a substance that binds to and activates a receptor and mimics the effect of a natural neurotransmitter or hormone
ex. phenylephrine
major locations of A2 receptors
smooth muscle in blood vessels, pancreatic cells, and platelets.
In terms of excitation and inhibition, what is the difference between the somatic and the autonomic?
somatic always excites, ANS can do both
Define B3 receptors
only found in brown adipose tissue and their activation causes thermogenesis
what is autonomic tone and what regulates it
the balance between sympathetic and parasympathetic activity
regulated by hypothalamus
What do Alpha 1 and Beta 1 produce?
excitation
What are the two types of neurotransmitters in the ANS?
ACh and NE
What are the 5 major prevertebral ganglion?
celiac, superior mesenteric, inferior mesenteric, aorticorenal, and renal
Where are terminal ganglia located?
close to or within the wall of a visceral organ
How do alpha and beta receptors react to NE and epinephrine?
NE stimulates alpha receptors more strongly than beta
epinephrine is a potent stimulator of both