Animal Hormones Flashcards
Performance enhancing drugs and order of the general effect on the body
SteroidsTakes testosterone-> binds to cell receptors-> alters gene expression
The main effect of steroids and side effects
Alters gene expressionCancer and heart,kidney,liver disease
Hormones are _____ and what is the speed of its communication and distance in the body it travels
Chemical messagesSlowDistance cells of the body
Hormones control ________ processes. Not useful for ________
Long term physiological processesNot for rapid reactions
Endocrine cells ________ into the ____ and ______
Secrete hormones into the interstitial space & blood stream (far away)
Exocrine cells _____ into ____ connected to the ______
Secrete substances into ducts connected to the outside world
Epithilial cells
Cells that “face” outside world
2 types of secreted hormones and general properties they share
Autocrine and paracrineReleased in small amounts, inactivated by enzymes, or taken up by local cells.Never get into the circulatory system (blood stream)
Describe autocrine hormones
Hormones acting on the secreting cell itself. Think “automatic”
Describe paracrine hormones
Hormones that act on cells near the site of release. Think “para” as “panoramic”
Describe circulatory hormones
Diffuse into blood streamLatches on to cell receptor to trigger a responseThe same hormone can have different responses
Example of a circulatory hormone, how it works, and effects
Epinephrine (aka adrenaline)Reaction to emergency causes adrenal cells in the kidney to secrete epinephrineHeart beats faster and strongerBlood vessels constrict to send more blood to musclesGlycogen broken to glucose in liverFats also used for energy (in liver)
3 main hormone groups
Peptides/proteinsSteroidsAmine hormones
Properties of peptide/protein hormonesExamples?
Water soluble (polar)Transported by vesiclesReceptors on surface of cellsSignal cascades into the cell Growth hormones and insulin
Properties of steroidsExamples
Lipid solubleCholesterol are the building blocksMembrane permeabl -can diffuse in and out of cellsNeeds carrier protein in bloodReceptors in cytoplasm and nucleusInteracts with DNA for altering gene expressionSuper small concentrationsEstrogen
Properties of amine hormonesExamples
Derivatives of amino acid tyrosineBoth lipid and water solubleAdrenaline/epinephrine
Peptide hormone receptors are
Large Glycoproteins on the cell surface
Receptors for steroids
Inside cell (cytoplasm/nucleus)Include intercellular receptors that alter gene expression
Endocrine glands- describe and how many major glands are there in vertebrates
Single cells that secrete hormones that congregate into clusters9 major glands
Pituitary gland - describe and locate
The link between nervous systemand endocrine glands.At the bottom of the skull and attached to the hypothalamus
Two parts of the pituitary gland and what they do
Posterior- releases 2 hormones (antidiuretic, oxytocin)-Made by neurons in hypothalamus (neural hormones)-Packaged in vesiclesAnterior-controlled by neurohormones from hypothalamus-releases 4 tropic hormones and other non tropic hormones
What are tropic hormones and list the main ones
Hormones that control other endocrine glandsArenocortico-tropinThyro-tropinLeutinizingFollicle-stimulating
Describe growth hormone and special cases
191 amino acidsPromotes growth in tissuesGigantism -too muchDwarfism - too little
Describe the pancreas
Functions mainly exocrine but endocrine gland as well
Where are exocrine products from the pancreas delivered?
To the intestine via pancreatic duct
What is the endocrine part of the pancreas comprised of?
Islets of Langerhans