Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Advanced Pharm Fall 24' > Analgesic Drugs > Flashcards

Analgesic Drugs Flashcards

1
Q

What is the drug class of Aspirin?

A

Nonsteroidal Anti-Inflammatory Drug (NSAID)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the mechanism of action of Aspirin?

A

Irreversible inhibition of COX-1 and COX-2 by covalent acetylation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the drug targets of Aspirin?

A

Cyclooxygenase enzymes (COX-1 and COX-2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the expected time for effect of Aspirin?

A

Varies based on dosage and condition being treated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the pharmacodynamics of Aspirin?

A

Anti-platelet aggregation at low doses, antipyretic and analgesic at intermediate doses, anti-inflammatory at high doses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the pharmacokinetics of Aspirin?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the absorption of Aspirin?

A

Complete

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the distribution of Aspirin?

A

Small volume of distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How is Aspirin excreted?

A

Renal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the metabolism of Aspirin?

A

Hepatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the dosage ranges for Aspirin?

A

Low doses (< 300 mg/day), intermediate doses (300-2400 mg/day), high doses (2400-4000 mg/day)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are key facts about Aspirin?

A

Avoid in patients with gout, risk of Reye syndrome in children with viral infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the drug class of Celecoxib?

A

Selective COX-2 Inhibitor (NSAID)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the mechanism of action of Celecoxib?

A

Reversible inhibition of COX-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the drug targets of Celecoxib?

A

COX-2 enzyme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the expected time for effect of Celecoxib?

A

Varies based on dosage and condition being treated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the pharmacodynamics of Celecoxib?

A

Anti-inflammatory and analgesic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are the pharmacokinetics of Celecoxib?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the absorption of Celecoxib?

A

Complete

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the distribution of Celecoxib?

A

Small volume of distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

How is Celecoxib excreted?

A

Renal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the metabolism of Celecoxib?

A

Hepatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are the dosage ranges for Celecoxib?

A

Varies based on condition being treated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What are key facts about Celecoxib?

A

Less gastrointestinal bleeding compared to non-selective NSAIDs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What is the drug class of Meloxicam?

A

Selective COX-2 Inhibitor (NSAID)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What is the mechanism of action of Meloxicam?

A

Reversible inhibition of COX-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What are the drug targets of Meloxicam?

A

COX-2 enzyme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What is the expected time for effect of Meloxicam?

A

Varies based on dosage and condition being treated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What are the pharmacodynamics of Meloxicam?

A

Anti-inflammatory and analgesic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

What are the pharmacokinetics of Meloxicam?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

What is the absorption of Meloxicam?

A

Complete

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

What is the distribution of Meloxicam?

A

Small volume of distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

How is Meloxicam excreted?

A

Renal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

What is the metabolism of Meloxicam?

A

Hepatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

What are the dosage ranges for Meloxicam?

A

Varies based on condition being treated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

What are key facts about Meloxicam?

A

Long-acting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

What is the drug class of Diclofenac?

A

Nonsteroidal Anti-Inflammatory Drug (NSAID)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

What is the mechanism of action of Diclofenac?

A

Reversible inhibition of COX-1 and COX-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

What are the drug targets of Diclofenac?

A

Cyclooxygenase enzymes (COX-1 and COX-2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

What is the expected time for effect of Diclofenac?

A

Varies based on dosage and condition being treated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

What are the pharmacodynamics of Diclofenac?

A

Analgesic, antipyretic, and anti-inflammatory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

What are the pharmacokinetics of Diclofenac?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

What is the absorption of Diclofenac?

A

Complete

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

What is the distribution of Diclofenac?

A

Small volume of distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

How is Diclofenac excreted?

A

Renal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

What is the metabolism of Diclofenac?

A

Hepatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

What are the dosage ranges for Diclofenac?

A

Varies based on condition being treated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

What are key facts about Diclofenac?

A

Short-acting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

What is the drug class of Ibuprofen?

A

Nonsteroidal Anti-Inflammatory Drug (NSAID)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

What is the mechanism of action of Ibuprofen?

A

Reversible inhibition of COX-1 and COX-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

What are the drug targets of Ibuprofen?

A

Cyclooxygenase enzymes (COX-1 and COX-2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

What is the expected time for effect of Ibuprofen?

A

Varies based on dosage and condition being treated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

What are the pharmacodynamics of Ibuprofen?

A

Analgesic, antipyretic, and anti-inflammatory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

What are the pharmacokinetics of Ibuprofen?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

What is the absorption of Ibuprofen?

A

Complete

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

What is the distribution of Ibuprofen?

A

Small volume of distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

How is Ibuprofen excreted?

A

Renal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

What is the metabolism of Ibuprofen?

A

Hepatic

59
Q

What are the dosage ranges for Ibuprofen?

A

Varies based on condition being treated

60
Q

What are key facts about Ibuprofen?

A

Short-acting

61
Q

What is the drug class of Indomethacin?

A

Nonsteroidal Anti-Inflammatory Drug (NSAID)

62
Q

What is the mechanism of action of Indomethacin?

A

Reversible inhibition of COX-1 and COX-2

63
Q

What are the drug targets of Indomethacin?

A

Cyclooxygenase enzymes (COX-1 and COX-2)

64
Q

What is the expected time for effect of Indomethacin?

A

Varies based on dosage and condition being treated

65
Q

What are the pharmacodynamics of Indomethacin?

A

Analgesic, antipyretic, and anti-inflammatory

66
Q

What are the pharmacokinetics of Indomethacin?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

67
Q

What is the absorption of Indomethacin?

A

Complete

68
Q

What is the distribution of Indomethacin?

A

Small volume of distribution

69
Q

How is Indomethacin excreted?

A

Renal

70
Q

What is the metabolism of Indomethacin?

A

Hepatic

71
Q

What are the dosage ranges for Indomethacin?

A

Varies based on condition being treated

72
Q

What are key facts about Indomethacin?

A

Short-acting

73
Q

What is the drug class of Ketorolac?

A

Nonsteroidal Anti-Inflammatory Drug (NSAID)

74
Q

What is the mechanism of action of Ketorolac?

A

Reversible inhibition of COX-1 and COX-2

75
Q

What are the drug targets of Ketorolac?

A

Cyclooxygenase enzymes (COX-1 and COX-2)

76
Q

What is the expected time for effect of Ketorolac?

A

Varies based on dosage and condition being treated

77
Q

What are the pharmacodynamics of Ketorolac?

A

Analgesic, antipyretic, and anti-inflammatory

78
Q

What are the pharmacokinetics of Ketorolac?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

79
Q

What is the absorption of Ketorolac?

A

Complete

80
Q

What is the distribution of Ketorolac?

A

Small volume of distribution

81
Q

How is Ketorolac excreted?

A

Renal

82
Q

What is the metabolism of Ketorolac?

A

Hepatic

83
Q

What are the dosage ranges for Ketorolac?

A

Varies based on condition being treated

84
Q

What are key facts about Ketorolac?

A

Short-acting

85
Q

What is the drug class of Acetaminophen?

A

Analgesic and Antipyretic

86
Q

What is the mechanism of action of Acetaminophen?

A

Inhibition of COX enzymes in the central nervous system

87
Q

What are the drug targets of Acetaminophen?

A

Cyclooxygenase enzymes (COX-1 and COX-2)

88
Q

What is the expected time for effect of Acetaminophen?

A

Varies based on dosage and condition being treated

89
Q

What are the pharmacodynamics of Acetaminophen?

A

Analgesic and antipyretic

90
Q

What are the pharmacokinetics of Acetaminophen?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

91
Q

What is the absorption of Acetaminophen?

A

Complete

92
Q

What is the distribution of Acetaminophen?

A

Small volume of distribution

93
Q

How is Acetaminophen excreted?

A

Renal

94
Q

What is the metabolism of Acetaminophen?

A

Hepatic

95
Q

What are the dosage ranges for Acetaminophen?

A

Varies based on condition being treated

96
Q

What are key facts about Acetaminophen?

A

Risk of hepatotoxicity at high doses

97
Q

What is the drug class of Glucocorticoids?

A

Corticosteroids

98
Q

What is the mechanism of action of Glucocorticoids?

A

Inhibition of phospholipase A2 and suppression of immune response

99
Q

What are the drug targets of Glucocorticoids?

A

Glucocorticoid receptors

100
Q

What is the expected time for effect of Glucocorticoids?

A

Varies based on dosage and condition being treated

101
Q

What are the pharmacodynamics of Glucocorticoids?

A

Anti-inflammatory and immunosuppressive

102
Q

What are the pharmacokinetics of Glucocorticoids?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

103
Q

What is the absorption of Glucocorticoids?

A

Complete

104
Q

What is the distribution of Glucocorticoids?

A

Small volume of distribution

105
Q

How are Glucocorticoids excreted?

A

Renal

106
Q

What is the metabolism of Glucocorticoids?

A

Hepatic

107
Q

What are the dosage ranges for Glucocorticoids?

A

Varies based on condition being treated

108
Q

What are key facts about Glucocorticoids?

A

Risk of adrenal suppression with long-term use

109
Q

What is the drug class of Abatacept?

A

Immunomodulator

110
Q

What is the mechanism of action of Abatacept?

A

Inhibition of T-cell activation

111
Q

What are the drug targets of Abatacept?

A

CD80 and CD86 on antigen-presenting cells

112
Q

What is the expected time for effect of Abatacept?

A

Varies based on dosage and condition being treated

113
Q

What are the pharmacodynamics of Abatacept?

A

Immunosuppressive

114
Q

What are the pharmacokinetics of Abatacept?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

115
Q

What is the absorption of Abatacept?

A

Complete

116
Q

What is the distribution of Abatacept?

A

Small volume of distribution

117
Q

How is Abatacept excreted?

A

Renal

118
Q

What is the metabolism of Abatacept?

A

Hepatic

119
Q

What are the dosage ranges for Abatacept?

A

Varies based on condition being treated

120
Q

What are key facts about Abatacept?

A

Risk of serious infections

121
Q

What is the drug class of Rituximab?

A

Monoclonal Antibody

122
Q

What is the mechanism of action of Rituximab?

A

Binding to CD20 on B-cells

123
Q

What are the drug targets of Rituximab?

A

CD20 on B-cells

124
Q

What is the expected time for effect of Rituximab?

A

Varies based on dosage and condition being treated

125
Q

What are the pharmacodynamics of Rituximab?

A

Immunosuppressive

126
Q

What are the pharmacokinetics of Rituximab?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

127
Q

What is the absorption of Rituximab?

A

Complete

128
Q

What is the distribution of Rituximab?

A

Small volume of distribution

129
Q

How is Rituximab excreted?

A

Renal

130
Q

What is the metabolism of Rituximab?

A

Hepatic

131
Q

What are the dosage ranges for Rituximab?

A

Varies based on condition being treated

132
Q

What are key facts about Rituximab?

A

Risk of serious infections

133
Q

What is the drug class of Adalimumab?

A

Monoclonal Antibody

134
Q

What is the mechanism of action of Adalimumab?

A

Binding to TNF-alpha

135
Q

What are the drug targets of Adalimumab?

A

TNF-alpha

136
Q

What is the expected time for effect of Adalimumab?

A

Varies based on dosage and condition being treated

137
Q

What are the pharmacodynamics of Adalimumab?

A

Immunosuppressive

138
Q

What are the pharmacokinetics of Adalimumab?

A

Absorbed completely, negligible first-pass hepatic metabolism, tightly bound to serum proteins, small volume of distribution

139
Q

What is the absorption of Adalimumab?

A

Complete

140
Q

What is the distribution of Adalimumab?

A

Small volume of distribution

141
Q

How is Adalimumab excreted?

A

Renal

142
Q

What is the metabolism of Adalimumab?

A

Hepatic

143
Q

What are the dosage ranges for Adalimumab?

A

Varies based on condition being treated

144
Q

What are key facts about Adalimumab?

A

Risk of serious infections

Advanced Pharm Fall 24' (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions