Aminoglucosidos Flashcards

1
Q

Mecanismo de acción de los Aminoglucosidos

A

se unen a la subunidad ribosomica 30S y 16S (estreptomicina solo) causando una lectura incorrecta generando proteínas anómalas causando destruccion de la membrana celular son Bactericidas.

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2
Q

CI Aminoglucosidos

A

Niños embarazadas

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3
Q

EA Aminoglucosidos

A

Ototoxicidad y Nefrotoxicicidad

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4
Q

Espectro Aminoglucosidos

A

Bacterias gram negativas aerobias

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5
Q

Aminoglucosidos de 1era generación

A

Neomicina Estreptomicina y Kanamicina (NEK)

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6
Q

Aminoglucosidos de 2da generación

A

Netilmicina Tobramicina Amikacina Gentamicina Paramonicina/Aminosidina

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7
Q

Aminoglucosido vía de administración oral o tópica la cual es muy poco absorbible y es por esto que se da para preparación y/ profilaxis de infección intestinal previo a Qx

A

Neomicina

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8
Q

EA Neomicina

A

Es el Aminoglucosido mas nefrotoxico mayor riesgo bloqueó neuromuscular

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9
Q

Tx #1 Tularemia

A

Estreptomicina

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10
Q

Tx Peste

A

Estreptomicina o gentamicina

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11
Q

Tx brucellosis combinado con Doxiciclina

A

Estreptomicina

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12
Q

Tx primera línea de Tuberculosis

A

Estreptomicina

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13
Q

EA Estreptomicina

A

Es la Menos nefrotoxica pero causa Escotomas

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14
Q

Aminoglucosidos de segunda generación que tiene un amplio espectro contra bacterias gram negativas multiresistente nosocomial

A

Amikacina

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15
Q

EA Amikacina

A

es la mas Ototoxica

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16
Q

Aminoglucosido 2da generación VA inhalada para PREVENIR pseudomona aureginosa en px con fibrosis quistica

A

Tobramicina (si ya está establecida Piperacilina+tazobactam)

17
Q

UT Paromomicina/aminosidina

A

Amebiasis intestinal por entamoeba histoliyca