Acute Interstitial Nephritis Flashcards

1
Q

What drugs commonly cause acute interstitial nephritis?

A

Abx most common:
penicillin
rifampicin

Others:
NSAIDs
allopurinol
furosemide

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2
Q

What systemic diseases can cause acute interstitial nephritis?

A

SLE
sacroidosis
Sjogrens

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3
Q

What infections can cause acute interstitial nephritis?

A

Hanta virus
staphylococci

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4
Q

Describe AIN on histology

A
  • marked interstitial oedema
  • interstitial infiltrate in the connective tissue between renal tubules
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5
Q

Clinical features of AIN

A

Fever
rash
arthralgia
eosinophilia
mild renal impairment
hypertension

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6
Q

What investigations can be used to help diagnose AIN?

A

sterile pyuria
white cell casts

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7
Q

Which condition(s) does the following describe:

Young female with fever, weight loss and painful, red eyes.

Urinalysis is positive for leukocytes and protein.

A

Tubulointerstitial nephritis with uveitis

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8
Q
A
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