Abdomen and Pelvic Cavity Flashcards
what is the boundary where the abdominal cavity becomes the pelvic cavity
pubic symphysis, L5 level
what happens to urine production if there is a drop in blood pressure
it goes down to try to conserve water and therefore blood pressure
what three structures make up the lower urinary tract
ureters
bladder
urethra
what is the flow of urine
kidney
ureters
bladder
urethra
explain how kidneys regulate fluid and electrolyte balance
regulate osmolarity by either conserving or eliminating water and electrolytes (sodium, potassium, calcium)
explain how kidneys excrete metabolic wastes
they filter out CO2, phosphates, and nitrogenous wastes (urea, ammonia, uric acid, and creatinine)
eliminate them via urine
how is urea produced
it is a waste product made when your liver breaks down protein
how is uric acid produced
chemical created when the body breaks down purines
how is creatinine produced
waste product of creatine
explain how kidneys maintain acid-base balance
regulates blood pH by conserving or eliminating hydrogen and bicarbonate ions
what is the optimal pH range for the body
7.35-7.45
what happens to pH if you remove hydrogen ions
pH increases
what three “hormones” do kidneys secrete
renin
erythropoietin
*prostaglandins - not technically a hormone
what does renin do
converts angiotensinogen into angiotensin 1 in the RAAS system
eventually, vessels constrict which causes hypertension and an increase in blood pressure
helps to maintain blood pressure
what does erythropoietin do
regulates making of red blood cells (erythropoiesis)
can increase red blood cell formation to combat anemia
what are protaglandins and what do they do
lipids made at sites of infection/damage
regulate renal blood flow and glomerular filtration rate
what substances do the kidneys detoxify in the blood
heavy metals
excess salt
excess vitamin C
how do kidneys regulate vitamin D metabolism
convert inactive form of vitamin D into active form (calcitriol)
what is gluconeogenesis
making of new glucose
can be done by the kidneys
what 5 heavy metals should we only see trace amounts of in the blood
chromium
copper
iron
manganese
zinc
*too much of these in the blood could indicate that the kidneys are not functioning properly
what percentage of kidney failure will you have to be at to be symptomatic
75% failure
how is kidney failure determined
high creatinine levels
what happens when you have damaged kidneys
less buffering (pH maintenance) capacity
more phophate, less calcium (muscle twitching)
more sodium, water, and edema
more potassium, hyperkalemia, cardiac muscles affected
what is hyperkalemia
too much potassium in the blood
typically due to kidney failure
what are the four external layers of the kidney from superficial to deep
pararenal (paranephric) fat capsule
renal fascia (Gerota’s fascia)
adipose capsule (perirenal or perinephric fat capsule)
renal capsule
where would you find paranephric (pararenal) fat
on posterior region of kidney
what does the renal fascia (gerota’s fascia) do
anchors kidney to peritoneum and muscles of posterior abdominal wall (psoas major and quadratus)
what does the adipose capsule (perirenal or perinephric fat capsule) do
found within the renal fascia directly touching the kidney
keeps kidneys in place and shields them from physical shock
what does the renal capsule do
covers exterior of kidney
protects kidney from outside infection and physical trauma
invaginates to become outer layer of calyces and pelvis
how much does a kidney weigh in both males and females
female: 130 g
male: 160 g
how are the structures entering the hilum of the kidney from anterior to posterior
renal vein
renal artery
nerves
lymph vessels
ureters
what is the renal sinus and what does it do
made up of calyces, pelvis, and fat
anchors vessels in place
how is the kidney broken up
superior pole (at the end closest to the adrenal gland)
lateral border (opposite the hilum)
innferior pole (at the end farthest from the adrenal gland)
where is the right kidney located
slightly inferior due to the liver
where is the left kidney located
between T11-L2 vertebrae
higher than right kidney becuase no liver on that side
which ribs protect the kidneys
the floating ribs (11+12)
what structures do you find around the right kidney
liver
hepatic flexture
duodenum
IVC
psoas muscle
what structures do you find around the left kidney
descending colon
ligament of treitz
psoas muscle
what are kidneys like during utero
start with 8 lobes
start out in the pelvis then ascend to the abdomen
what are the three distinct regions of the internal kidney
renal cortex
renal medulla
renal pelvis
what is the renal cortex
rim of reddish-brown tissue around the inside of the kidney
holds 95% of all kidneys blood vessels
what is the renal medulla
Inner portion of kidney deep to the cortex
includes several renal pyramids and the columns between them
darkened due to lack of blood vessels
what are renal columns (of Bertin)
invaginations of the renal cortex between renal pyramids
has branches of the renal artery going to the outer cortex
what are nephrons and where are they found
filtering apparatus made of renal corpuscle and renal tubule
found within the cortex with extensions into the medulla
what do the renal corpuscles do
made of glomerulus and its capsule
filters blood
what are renal tubules and what do they do
made of proximal tubule, loop henle, and distal tubule
collect and modify filtrate
what are the two types of nephrons
cortical and juxtamedullary
what are some features of the cortical nephrons
make up 80% of nephrons
found primarily in renal cortex and have small nephron loops
what are some features of juxtamedullary nephrons
nephrons whose loop extends deep into the renal pyramid
what are the three portions of the collecting duct from cortex to minor calyx
cortical (within cortext)
medullary (within pyramid)
papillary (bottom of pyramid)
what is the papilla
bottom portion of renal pyramid
what makes up a major calyx
3-4 minor calyces
what makes the renal pelvis
2-3 major calyx
what is the ureteropelvic junction
constriction at the junction of the renal pelvis and ureter
what is a bifid renal pelvis
more than one renal pelvis
invasion of what two structures halves the survival rate of kidney cancer
renal vein or renal capsule
explain transitional cell cancer
cancer of the transitional epithelial cells
can occur in the pelvis, top of ureter, and bladder
treated by removing entire kidney and ureter
explain renal cell cancer
tumor of lining of small tubes in kidney
treated by removing kidney and a small portion of ureter
symptoms don’t present until it’s severe
most common in older men
explain nephrolithiasis
kidney stones
caused by dehydration, obesity, salt, etc.
pain radiates medially and inferiorly from lumbar region to pubic region
diagnosed through CT scan or intravenous pylogram
what is the arterial blood flow of the kidney
abdominal aorta
R + L renal arteries
segmental artery
interlobar artery
arcuate artery
interlobular (cortical radiate artery)
afferent arterioles
glomerulus
efferent arteriole
peritubular capillaries
what are peritubular capillaries and what do they do
branches from neighboring cortical nephrons (mixed)
supply blood to loops of cortical nephrons
what is the vasa recta and what does it do
ladder-like network of capillaries that arise from efferent arterioles (mixed)
allows juxtamedullary nephrons to control volume and concentration of urine