(8) Pain SLO Flashcards
Acetaminophen is associated with \_\_?\_\_. A. Bronchoconstriction B. Liver failure C. Urticaria D. Reye’s Syndrome E. Hyperkalemia
Liver Failure
Aspirin is associated with \_\_?\_\_ in kids with viral infections. A. Reye’s Syndrome B. GIT ulcers C. Respiratory distress Syndrome D. Urticaria E. Constipation
Reye’s Syndrome
Aspirin is associated with \_\_?\_\_ A. Gastric ulcers B. Respiratory distress Syndrome (bronchoconstriction) C. Urticaria D. Tinnitus E. All the above
Gastric ulcers Respiratory distress Syndrome (bronchoconstriction) Urticaria Tinnitus **ALL**
Aspirin is contraindicated in young patients with chicken pox or influenza due to the risk of \_\_?\_\_ A. Reye’s Syndrome B. Heart Attack C. Gastric ulcer D. Nose bleed E. Asthma attack
Reye’s Syndrome
Etanercept, and other biologic response modifier or disease-modifying antirheumatic drugs (DMARDs) and other immune modulators, are associated with __?__.
A. Fewer infections
B. Antibiotic effects
C. Increased risk of malignancy
D. No change in immune response
E. An increased risk of serious infection and pancytopenia
An increased risk of serious infection and pancytopenia
Fentanyl and morphine have short t ½ so are used to treat acute or break through pain, whereas \_\_?\_\_ has a very long t ½ so is used for chronic pain. A. Pentazocine B. Hydrocodone C. Meperidine D. Naltrexone E. Methadone
Methadone
Hydrocodone is metabolized by CYP2D6 to morphine, genetic expression varies. Having multiple copies of the gene would predispose the patient to \_\_?\_\_ related side effects? A. Cocaine B. Morphine C. Aspirin D. Acetaminophen E. Fentanyl
Morphine
NSAIDs are associated with \_\_?\_\_. A. GIT ulcers B. GIT pain, nausea and aggravation of pre-existing GIT diseases C. Urticaria D. Worsening congestive heart failure E. All the above
GIT ulcers GIT pain, nausea and aggravation of pre-existing GIT diseases Urticaria Worsening congestive heart failure **ALL**
Opioids are associated with __?__
A. Progressively decreased responsiveness so more drug is needed to get same effect.
B. Causing an overwhelming desire to take the drug
C. Tolerance
D. Dependence
E. All the above
Progressively decreased responsiveness so more drug is needed to get same effect.
Causing an overwhelming desire to take the drug
Tollerence
Dependence
ALL
Probenecid (Benuryl) increases the \_\_?\_\_ of penicillin antibiotics, sulfonamides and sulfonylureas. A. Renal secretion B. Plasma concentration C. Kidney excretion D. Plasma protein binding E. Liver metabolism
Plasma consentration
Which is a synthetic opioid analgesic available PO, SC, IV, IM, PR, sublingual, and buccal for moderate to severe pain? T ½ is 5-7 hours. It is NOT CONTROLLED. A. Methadone B. Tramadol C. Pentazocine D. Meperidine E. Buprenorphine
Tramadol (Ultram)
Which blocks renal tubular reabsorption of urate? It is used to increase uric acid excretion, to treat gout, and to decrease the renal secretion of penicillin antibiotics. A. Rasburicase B. Etanercept C. Colchicine D. Probenecid E. Allopurinol
Probenecid (Benuryl)
Which is a C-II opioid analgesic used PO, IM, IV, PR, epidural, and intrathecal with a t ½ of 1.5-7 hours to relieve moderate to severe pain? It is derived from the poppy and is commonly used in patient controlled analgesia devices (PCA). A. Hydrocodone B. Fentanyl C. Morphine D. Diphenoxylate E. Naltrexone
Morphine (MS Contin)
Which is a C-II synthetic opioid analgesic available PO, IV, and IM for acute pain and obstetric or post-op analgesia? T ½ is about 3-4 hours. It has a boxed warning limiting use to less than 12 weeks. A. Meperidine B. Fentanyl C. Methadone D. Morphine E. Buprenorphine
Meperidine (Demerol)
Which is a C-II synthetic opioid analgesic available PO, IV, IM, SC (IM and SC not preferred) to treat chronic pain, opioid addiction and as an antitussive? T ½ highly variable 24-60 hours. A. Morphine B. Fentanyl C. Buprenorphine D. Methadone E. Meperidine
Methadone (Dolophine, Methadose)