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Pharmacology > (25) GI SLO > Flashcards

(25) GI SLO Flashcards

1
Q

All antiemetics are associated with __?__
A. Diarrhea if used chronically.
B. Masking the symptoms of overdose or the adverse effects of other drugs including antineoplastic agents.
C. Suicidal ideation, increased prolactin levels, hypertension
D. Drug-induced cataracts
E. Atonic, dilated colon with prolonged use

A

Masking the symptoms of overdose or the adverse effects of other drugs including antineoplastic agents.

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2
Q

All antiemetics are associated with __?__
A. Masking the symptoms of GI obstruction, brain tumors, head trauma, and Reye’s syndrome
B. Abortion in pregnant women
C. Masking the symptoms of overdose or the adverse effects of other drugs including antineoplastic agents.
D. Drug-induced cataracts
E. Overheating, blurred vision, sedation, dry mouth, constipation, and urinary retension

A

Masking the symptoms of GI obstruction, brain tumors, head trauma, and Reye’s syndrome

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3
Q 
Aprepitant significantly decreases the \_\_?\_\_ in warfarin patients so additional monitoring is required.
A. 	Half life
B. 	Appetite
C. 	Weight
D. 	Body temperature
E. 	Prothrombin time
A

Prothrombin time

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4
Q

Chronic corticosteroid use is associated with __?__
A. Atonic, dilated colon with prolonged use
B. Masking the symptoms of overdose or the adverse effects of other drugs including antineoplastic agents.
C. Drug-induced cataracts
D. Diarrhea if used chronically.
E. Suicidal ideation, increased prolactin levels, hypertension

A

Drug-induced cataracts

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5
Q

H2 receptor blockers, antacids and proton pump inhibitors all reduce gastric acidity and are associated with __?__
A. Masking the symptoms of overdose or the adverse effects of other drugs including antineoplastic agents.
B. Suicidal ideation, increased prolactin levels, hypertension
C. Drug-induced cataracts
D. Atonic, dilated colon with prolonged use
E. Diarrhea if used chronically.

A

Diarrhea if used chronically.

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6
Q

Laxatives including Bisocodyl and magnesium hydroxide are associated with __?__
A. Drug-induced cataracts
B. Atonic, dilated colon with prolonged use
C. Diarrhea if used chronically.
D. Masking the symptoms of overdose or the adverse effects of other drugs including antineoplastic agents.
E. Suicidal ideation, increased prolactin levels, hypertension

A

Atonic, dilated colon with prolonged use

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7
Q 
Loperamide normally cannot accumulate in the brain because \_\_?\_\_ pump(s) it right out.
A. 	Phase 2 enzymes
B. 	P-Glycoprotein
C. 	P450's
D. 	Acetyl Cholinesterase
E. 	Phase 1 enzymes
A

P-Glycoprotein

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8
Q

Many anticholinergics are associated with __?__
A. Abortion in pregnant women
B. Masking the symptoms of overdose or the adverse effects of other drugs including antineoplastic agents.
C. Overheating, blurred vision, sedation, dry mouth, constipation, and urinary retention
D. Masking the symptoms of GI obstruction, brain tumors, head trauma, and Reye’s syndrome
E. Drug-induced cataracts

A

Overheating, blurred vision, sedation, dry mouth, constipation, and urinary retention

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9
Q

Metoclopramide is associated with __?__
A. Atonic, dilated colon with prolonged use
B. Drug-induced cataracts
C. Masking the symptoms of overdose or the adverse effects of other drugs including antineoplastic agents.
D. Diarrhea if used chronically.
E. Suicidal ideation, increased prolactin levels, hypertension

A

Suicidal ideation, increased prolactin levels, hypertension

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10
Q

Misoprostol is associated with __?__
A. Abortion in pregnant women
B. Overheating, blurred vision, sedation, dry mouth, constipation, and urinary retention
C. Masking the symptoms of overdose or the adverse effects of other drugs including antineoplastic agents.
D. Masking the symptoms of GI obstruction, brain tumors, head trauma, and Reye’s syndrome
E. Drug-induced cataracts

A

Abortion in pregnant women

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11
Q

The acronym RINV means?
A. Radiation Induced Nausea and Vomiting
B. Reality Insurance Never Verified
C. Radically Incited Nausea and Vomiting
D. Racially Induced Nausea and Vomiting
E. Radiation Induced Nuclear Void

A

Radiation Induced Nausea and Vomiting

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12
Q

What are the indications for Aprepitant (Emend)?
A. Adjunct to treat CINV and PONV (with a corticosteroid and/or a 5-HT3 blocker)
B. Zillions of other indications. Often used for PONV & CINV (a drug of choice).
C. PONV and CINV, also for schizophrenia and non-psychotic anxiolysis.
D. CINV and AIDs HAART-induced emesis and anorexia, also anorexia in Alzheimer’s patients
E. CINV, RINV and PONV

A

Adjunct to treat CINV and PONV (with a corticosteroid and/or a 5-HT3 blocker)

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13
Q

What are the indications for Bisacodyl (Dulcolax)
A. GERD, hypersecretory conditions
B. Antiemetic
C. GI stimulant (laxative) for diabetic gastroparesis and to increase GI movement during small bowel intubation or to promote barium movement through GIT. As an anti emetic for PONV, CINV, and GERD. Also stimulates lactation.
D. Enzyme replacement used as an aid to digest and absorb fats, proteins and carbohydrates in people without the ability to generate the native enzymes
E. Laxative for bowel preparation and prevention of constipation after surgery, MI or obstetrical delivery; acute constipation

A

Laxative for bowel preparation and prevention of constipation after surgery, MI or obstetrical delivery; acute constipation

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14
Q

What are the indications for Dexamethasone?
A. Adjunct to CINV and PONV (with a corticosteroid and/or a 5-HT3 blocker)
B. CINV and AIDs HAART-induced emesis and anorexia, also anorexia in Alzheimer’s patients
C. CINV, RINV and PONV
D. PONV and CINV, also for schizophrenia and non-psychotic anxiolysis.
E. Zillions of other indications. Often used for PONV & CINV (a drug of choice).

A

Zillions of other indications. Often used for PONV & CINV (a drug of choice).

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15
Q

What are the indications for Diphenhydramine (Benadryl)?
A. Traveler’s diarrhea, and irritable bowel syndrome
B. Motion sickness
C. PONV; also anxiolytic, sedative hypnotic, amnesiac, anticonvulsant
D. Nausea associated with motion sickness; also sedative hypnotic and anti-PD/EPS. Used to treat all types of allergic reactions
E. Motion sickness and PONV. As an adjunct to peptic ulcer therapy and in combo products.

A

Nausea associated with motion sickness; also sedative hypnotic and anti-PD/EPS. Used to treat all types of allergic reactions

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16
Q

What are the indications for Dronabinol (Marinol)?
A. Zillions of other indications. Often used for PONV & CINV (a drug of choice).
B. CINV, RINV and PONV
C. PONV and CINV, also for schizophrenia and non-psychotic anxiolysis.
D. CINV and AIDs HAART-induced emesis and anorexia, also anorexia in Alzheimer’s patients
E. CINV and PONV

A

CINV and AIDs HAART-induced emesis and anorexia, also anorexia in Alzheimer’s patients

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17
Q

What are the indications for Famotidine (Pepcid) & Ranitidine (Zantac)?
A. To prevent NSAID related GI ulcers in adults at high risk.
B. Reduce GI hyperacidity, and uric acid cystalluria; adjunct for severe diarrhea as a bicarbonate replacement
C. GERD, gastric ulcer, pathological hypersecretory conditions, in combo with antibiotics to treat Helicobacter pylori infection
D. GERD, GI ulcers, heartburn, pathological hypersecretion syndrome.
E. Short-term ulcer treatment, usually for ulcers due to chemotherapy or radiation (forms a proteinaceous glob over ulcer).

A

GERD, GI ulcers, heartburn, pathological hypersecretion syndrome.

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18
Q

What are the indications for Ginger?
A. CINV, RINV and PONV
B. Used off label as a rescue anti emetic for severe emesis
C. Motion sickness, PONV, morning sickness, and CINV
D. Adjunct to CINV and PONV (with a corticosteroid and/or a 5-HT3 blocker)
E. Zillions of other indications. Often used for PONV & CINV (a drug of choice).

A

Motion sickness, PONV, morning sickness, and CINV

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19
Q

What are the indications for Loperamide (Imodium)?
A. Motion sickness
B. Traveler’s diarrhea, and irritable bowel syndrome
C. Nausea associated with motion sickness; also sedative hypnotic and anti-PD/EPS. Used to treat all types of allergic reactions
D. PONV; also anxiolytic, sedative hypnotic, amnesiac, anticonvulsant
E. Motion sickness and PONV. As an adjunct to peptic ulcer therapy and in combo products.

A

Traveler’s diarrhea, and irritable bowel syndrome

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20
Q

What are the indications for Lorazepam (Ativan)?
A. PONV; also anxiolytic, sedative hypnotic, amnesiac, anticonvulsant
B. Nausea associated with motion sickness; also sedative hypnotic and anti-PD/EPS. Used to treat all types of allergic reactions
C. Traveler’s diarrhea, and irritable bowel syndrome
D. Motion sickness
E. Motion sickness and PONV. As an adjunct to peptic ulcer therapy and in combo products.

A

PONV; also anxiolytic, sedative hypnotic, amnesiac, anticonvulsant

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21
Q

What are the indications for Meclizine (Bonine, Antivert)?
A. Motion sickness and PONV. As an adjunct to peptic ulcer therapy and in combo products.
B. Traveler’s diarrhea, and irritable bowel syndrome
C. PONV; also anxiolytic, sedative hypnotic, amnesiac, anticonvulsant
D. Motion sickness
E. Nausea associated with motion sickness; also sedative hypnotic and anti-PD/EPS. Used to treat all types of allergic reactions

A

Motion sickness

22
Q

What are the indications for Metoclopramide (Reglan)?
A. Laxative for bowel preparation and prevention of constipation after surgery, MI or obstetrical delivery; acute constipation
B. GI stimulant (laxative) for diabetic gastroparesis and to increase GI movement during small bowel intubation or to promote barium movement through GIT. As an anti emetic for PONV, CINV, and GERD. Also stimulates lactation.
C. Enzyme replacement used as an aid to digest and absorb fats, proteins and carbohydrates in people without the ability to generate the native enzymes
D. Antidiarrheal
E. GERD, hypersecretory conditions

A

GI stimulant (laxative) for diabetic gastroparesis and to increase GI movement during small bowel intubation or to promote barium movement through GIT. As an anti emetic for PONV, CINV, and GERD. Also stimulates lactation

23
Q

What are the indications for Misoprostol (Cytotec)?
A. To prevent NSAID related GI ulcers in adults at high risk.
B. Reduce GI hyperacidity, and uric acid cystalluria; adjunct for severe diarrhea as a bicarbonate replacement
C. GERD, GI ulcers, heartburn, pathological hypersecretion syndrome.
D. Short-term ulcer treatment, usually for ulcers due to chemotherapy or radiation (forms a proteinaceous glob over ulcer).
E. GERD, gastric ulcer, pathological hypersecretory conditions, in combo with antibiotics to treat Helicobacter pylori infection

A

To prevent NSAID related GI ulcers in adults at high risk.

24
Q

What are the indications for Omeprazole (Prilosec)?
A. GERD, GI ulcers, heartburn, pathological hypersecretion syndrome.
B. Reduce GI hyperacidity, and uric acid cystalluria; adjunct for severe diarrhea as a bicarbonate replacement
C. GERD, gastric ulcer, pathological hypersecretory conditions, in combo with antibiotics to treat Helicobacter pylori infection
D. To prevent NSAID related GI ulcers in adults at high risk.
E. Short-term ulcer treatment, usually for ulcers due to chemotherapy or radiation (forms a proteinaceous glob over ulcer).

A

GERD, gastric ulcer, pathological hypersecretory conditions, in combo with antibiotics to treat Helicobacter pylori infection

25
Q

What are the indications for Ondansetron (Zofran)?
A. CINV and PONV
B. CINV and AIDs HAART-induced emesis and anorexia, also anorexia in Alzheimer’s patients
C. PONV and CINV, also for schizophrenia and non-psychotic anxiolysis.
D. Zillions of other indications. Often used for PONV & CINV (a drug of choice).
E. CINV, RINV and PONV

A

CINV, RINV and PONV

26
Q

What are the indications for Pancrelipase (Ultrase)?
A. Laxative for short-term treatment of constipation
B. GI stimulant (laxative) for diabetic gastroparesis and to increase GI movement during small bowel intubation or to promote barium movement through GIT. As an anti emetic for PONV, CINV, and GERD. Also stimulates lactation.
C. Enzyme replacement used as an aid to digest and absorb fats, proteins and carbohydrates in people without the ability to generate the native enzymes
D. To prevent NSAID related GI ulcers in adults at high risk.
E. Short-term ulcer treatment, usually for ulcers due to chemotherapy or radiation (forms a proteinaceous glob over ulcer).

A

Enzyme replacement used as an aid to digest and absorb fats, proteins and carbohydrates in people without the ability to generate the native enzymes

27
Q

What are the indications for Prochlorperazine (Compazine)?
A. PONV and CINV, also for schizophrenia and non-psychotic anxiolysis.
B. CINV and AIDs HAART-induced emesis and anorexia, also anorexia in Alzheimer’s patients
C. Zillions of other indications. Often used for PONV & CINV (a drug of choice).
D. CINV, RINV and PONV
E. CINV and PONV

A

PONV and CINV, also for schizophrenia and non-psychotic anxiolysis.

28
Q

What are the indications for Propofol?
A. Motion sickness, PONV, morning sickness, and CINV
B. Zillions of other indications. Often used for PONV & CINV (a drug of choice).
C. CINV, RINV and PONV
D. Used off label as a rescue anti emetic for severe emesis
E. Adjunct to CINV and PONV (with a corticosteroid and/or a 5-HT3 blocker)

A

Used off label as a rescue anti emetic for severe emesis

29
Q

What are the indications for Scopolamine (Scopace, Transderm Scop)?
A. PONV; also anxiolytic, sedative hypnotic, amnesiac, anticonvulsant
B. Traveler’s diarrhea, and irritable bowel syndrome
C. Motion sickness and PONV. As an adjunct to peptic ulcer therapy and in combo products.
D. Nausea associated with motion sickness; also sedative hypnotic and anti-PD/EPS. Used to treat all types of allergic reactions
E. Motion sickness

A

Motion sickness and PONV. As an adjunct to peptic ulcer therapy and in combo products.

30
Q

What are the indications for Sodium bicarbonate
A. GERD, GI ulcers, heartburn, pathological hypersecretion syndrome.
B. To prevent NSAID related GI ulcers in adults at high risk.
C. Reduce GI hyperacidity, and uric acid cystalluria; adjunct for severe diarrhea as a bicarbonate replacement
D. GERD, gastric ulcer, pathological hypersecretory conditions, in combo with antibiotics to treat Helicobacter pylori infection
E. Short-term ulcer treatment, usually for ulcers due to chemotherapy or radiation (forms a proteinaceous glob over ulcer).

A

Reduce GI hyperacidity, and uric acid cystalluria; adjunct for severe diarrhea as a bicarbonate replacement

31
Q

What are the indications for Sucralfate (Carafate)?
A. GERD, gastric ulcer, pathological hypersecretory conditions, in combo with antibiotics to treat Helicobacter pylori infection
B. Short-term ulcer treatment, usually for ulcers due to chemotherapy or radiation (forms a proteinaceous glob over ulcer).
C. To prevent NSAID related GI ulcers in adults at high risk.
D. GERD, GI ulcers, heartburn, pathological hypersecretion syndrome.
E. Reduce GI hyperacidity, and uric acid cystalluria; adjunct for severe diarrhea as a bicarbonate replacement

A

Short-term ulcer treatment, usually for ulcers due to chemotherapy or radiation (forms a proteinaceous glob over ulcer).

32
Q 
What class of drug Bisacodyl?
A. 	Pancreatic digestive enzymes
B. 	Antiemetic
C. 	Prostaglandin E analog
D. 	Laxative
E. 	Anti-diarrheal
A

Laxative

33
Q

What class of drug is Aprepitant?
A. Substance P/Neurokinin 1 receptor antagonist
B. C-III cannabinoid antiemetic
C. 5-HT3 receptor antagonist antiemetic
D. Synthetic corticosteroid anti-inflammatory agent
E. Phenothiazine antiemetic

A

Substance P/Neurokinin 1 receptor antagonist

34
Q

What class of drug is Dexamethasone?
A. Synthetic corticosteroid anti-inflammatory agent
B. Substance P/Neurokinin 1 receptor antagonist
C. 5-HT3 receptor antagonist antiemetic
D. Phenothiazine antiemetic
E. C-III cannabinoid antiemetic

A

Synthetic corticosteroid anti-inflammatory agent

35
Q 
What class of drug is Diphenhydramine?
A. 	Antihistaminic 
B. 	Non-narcotic opioid-derivative anti-diarrheal
C. 	5-HT3 antagonist antiemetic
D. 	Anticholinergic anti emetic
E. 	C-III cannabionid anti emetic
A

Antihistaminic

36
Q

What class of drug is dronabinol?
A. C-III cannabinoid antiemetic and appetite stimulant
B. Synthetic corticosteroid anti-inflammatory agent
C. Phenothiazine anti emetic
D. 5-HT3 receptor antagonist anti emetic
E. Substance P/Neurokinin 1 receptor antagonist

A

C-III cannabinoid antiemetic and appetite stimulant

37
Q 
What class of drug is Loperamide?
A. 	Anticholinergic anti emetic
B. 	C-III cannabionid anti emetic
C. 	Non-narcotic opioid-derivative anti-diarrheal
D. 	5-HT3 antagonist antiemetic
E. 	Antihistaminic anti emetic
A

Non-narcotic opioid-derivative anti-diarrheal

38
Q

What class of drug is Ondansetron?
A. Substance P/Neurokinin 1 receptor antagonist
B. Synthetic corticosteroid anti-inflammatory agent
C. 5-HT3 receptor antagonist antiemetic
D. C-III cannabinoid antiemetic
E. Phenothiazine antiemetic

A

5-HT3 receptor antagonist antiemetic

39
Q

What class of drug is Prochlorperazine?
A. Substance P/Neurokinin 1 receptor antagonist
B. Phenothiazine antiemetic
C. C-III cannabinoid antiemetic
D. 5-HT3 receptor antagonist antiemetic
E. Synthetic corticosteroid anti-inflammatory agent

A

Phenothiazine antiemetic

40
Q 
What class of drug is Propofol?
A. 	Substance P/Neurokinin 1 receptor antagonist
B. 	Parenteral general anesthetic
C. 	Phenothiazine antiemetic
D. 	5-HT3 receptor antagonist antiemetic
E. 	C-III cannabinoid antiemetic
A

Parenteral general anesthetic

41
Q 
What class of drug is Scopolamine?
A. 	Antihistaminic anti emetic
B. 	Non-narcotic opioid-derivative anti-diarrheal
C. 	5-HT3 antagonist antiemetic
D. 	Anticholinergic anti emetic
E. 	C-III cannabionid anti emetic
A

Anticholinergic anti emetic

42
Q 
What class of drug Misoprostol?
A. 	Antiemetic
B. 	Laxative
C. 	Prostaglandin E analog
D. 	Pancreatic digestive enzymes
E. 	Anti-diarrheal
A

Prostaglandin E analog

43
Q 
What class of drug Omeprazole?
A. 	Proton pump inhibitor
B. 	Antiemetic
C. 	Antacid
D. 	Laxative
E. 	Anti-diarrheal
A

Proton pump inhibitor

44
Q 
What class of drug Pancrelipase?
A. 	Pancreatic digestive enzymes
B. 	Anti-diarrheal
C. 	Laxative
D. 	Prostaglandin E analog
E. 	Antiemetic
A

Pancreatic digestive enzymes

45
Q 
What class of drug sodium bicarbonate?
A. 	H2 antagonist
B. 	Laxative
C. 	Antacid
D. 	Antiemetic
E. 	Anti-diarrheal
A

Antacid

46
Q 
What class of drug sucralfate
A. 	Antacid
B. 	Laxative
C. 	Anti-diarrheal
D. 	Anti-peptic agent
E. 	Antiemetic
A

Anti-peptic agent

47
Q 
What class of drugs are cimetidine, famotidine and ranitidine?
A. 	5-HT3 antagonist
B. 	Proton pump inhibitor
C. 	1st generation antihistamine
D. 	H2 antagonist
E. 	2nd generation antihistamine
A

H2 antagonist

48
Q

What does the acronym CINV mean?
A. Cheap Ingestible = Nausea and Vomiting
B. Chemotherapy Induced Nausea and Vomiting
C. Certifiably Insane Nursing Venue
D. Captain Invisible’s Next Venture
E. Causes Infections, Nausea and Vomiting

A

Chemotherapy Induced Nausea and Vomiting

49
Q 
What does the acronym NVP mean?
A. 	Never Vomit on Patients
B. 	Nausea and Vomiting of Patients
C. 	Nearly Visible Pigment
D. 	Noticeably Vicious Patient
E. 	Nausea and Vomiting of Pregnancy
A

Nausea and Vomiting of Pregnancy

50
Q 
What does the acronym PONV mean?
A. 	Post-Op Nausea and Vomiting
B. 	Post-Op (patients) Never Vomit
C. 	Powerful Odors Nauseate Verily
D. 	Puking Objectives Need Verification
E. 	People Obviously Need Victory
A

Post-Op Nausea and Vomiting

51
Q 
Which of these is an antacid that may be used to treat TCA OD?
A. 	Ranitidine
B. 	Scopolamine
C. 	Sucralfate
D. 	Sodium bicarbonate
E. 	Omeprazole
A

Sodium bicarbonate

52
Q 
What class of drug is Magnesium hydroxide (Philips Milk of Magnesia)?
A. 	Bulk laxative
B. 	Synthetic corticosteroid
C. 	H2 antagonist
D. 	PGE analog
E. 	Pancreatic digestive enzyme
A

Bulk laxative

Pharmacology (30 decks)

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