(15) CV2 SLO Flashcards
Adenosine is antagonized by methylxanthines including \_\_?\_\_ A. Phenytoin B. Furosemide C. Digoxin D. Caffeine E. Dobutamine
Caffeine
Digoxin dosages require individualization. Which of the following variables should be taken into account when determining the dose to use?
A. Base dose on Lean body weight
B. Patient’s renal function a factor, base dose on estimated creatinine clearance
C. Age – infants, children and the elderly lower than adults
D. Concomitant diseases or concurrent medications that alter pharmacokinetics (e.g., alter potassium levels)
E. All of the above
All of the above
Dobutamine is inactivated by alkaline solutions including __?__
A. Sodium bicarbonate
B. Hydrochloride in gastric juices
C. Plasma
D. Dobutamine is inactive in all the listed solutions
E. Blood
Sodium bicarbonate
Which of the following is a Calcium channel blocker (CCB) given PO SID? A. Nitroglycerin B. Metoprolol C. Aliskiren D. Ranolazine E. Amlodipine
Amlodipine
Which of the following is a CCB given PO SID at bedtime (do not crush for extended release formulation) and TID-QID for other formulations. PO indicated for HTN and angina (all forms of angina) and tachyarrhythmis. An IV (given as injection over 2 minute period) for tachyarrhythmia conversion. A. Hydralazine B. Ranolazine C. Lidocaine D. Propranolol E. Verapamil
Verapamil
Which of the following is a CCB given PO TID or QID (extended-release capsule – SID), or IV (single bolus or for up to 24 hrs as IV Infusion). The PO form is indicated for HTN & Angina; the IV form is used for tachyarrhythmia control. A. Propranolol B. Diltiazem C. Ranolazine D. Furosemide E. Nitroglycerin
Diltiazem
Which of the following is a Class 1a Na+ channel blocker anti arrhythmic for ventricular tachyarrhythmias. Avail IM/IV and PO? A. Propranolol B. Procainamide C. Amiodarone D. Digoxin E. Adenosine
Procainamide
Which of the following is a Class 1b Na+ channel blocker anti arrhythmic for ventricular tachyarrhythmias. Available IV for tachyarrhythmias (and in zillions of other formulations as a topical local anesthetic)? A. Verapamil B. Lidocaine C. Adenosine D. Amiodarone E. Propranolol
Lidocaine
Which of the following is a Class 1b Na+ channel blocker anti arrhythmic for ventricular tachyarrhythmias? It is available PO as an AED and IV to control arrhythmias. A. Digoxin B. Verapamil C. Amiodarone D. Propranolol E. Phenytoin
Phenytoin
Which of the following is a Class 1c Na+ channel blocker anti arrhythmic for atrial and ventricular tachyarrhythmias. PO BID, but has a very long t ½ (up to 27 hrs), so steady-state may not be reached for days. Therefore, don’t change dose within 4 days (no more often than every 4 days)? A. Adenosine B. Diltiazem C. Propranolol D. Digoxin E. Flecainide
Flecainide
Which of the following is a Class III antiarrhythmic? It is available as an IV infusion to control ventricular tachyarrhythmias (high inter-individual variation for dose). PO requires a LOADING dose of around 1 gram/day for 1-3 weeks. Maintenance doses usually SID or BID 400 mg/day. A. Amiodarone B. Propranolol C. Digoxin D. Adenosine E. Verapamil
Amiodarone
Which of the following is a Class V antiarrhythmic that is only available as an IV only (very short t ½) for acute supraventricular tachycardia? A. Propranolol B. Lidocaine C. Adenosine D. Phenytoin E. Diltiazem
Adenosine
Which of the following is a Class V antiarrhythmic. It inhibits sodium potassium ATPase and is indicated for mild to moderate HF and atrial fibrillation. Avail PO and IV (can be given IM, but very painful, IV infusion preferred). A. Diltiazem B. Verapamil C. Propranolol D. Digoxin E. Lidocaine
Digoxin
Which of the following is a pFOX (partial fatty acid oxidase) inhibitor for chronic angina? A. Ranolazine B. Verapamil C. Nitroglycerin D. Diltiazem E. Amlodipine
Ranolazine
Which of the following is a short acting nitrate vasodilator indicated for typical angina or MI? It is available in PO, transdermal, IV, topical formulations. A. Diltiazem B. Verapamil C. Nitroglycerin D. Amlodipine E. Ranolazine
Nitroglycerin