(21) Micro 5 SLO Flashcards
Amphotericin B is associated with __?__
A. Numerous drug interactions due to P450 inhibition
B. 8th cranial nerve damage
C. Fever, shaking, chills, hypotension, anorexia, nausea, vomiting, headache and tachypnea.
D. Liver failure, severe allergic reactions and arrhythmias.
E. None of the listed answers are correct
Fever, shaking, chills, hypotension, anorexia, nausea, vomiting, headache and tachypnea
Fluconazole (Diflucan) is a potent P450 inhibitor with lots of drug interactions. What is the general effect on drugs having fluconazole interaction problems?
A. Treatment failure occurs due to decreasing levels of the other drug
B. Cancer develops
C. Toxicity occurs due to increasing the levels of the “other” drug
D. Treatment failure occurs for the condition treated by fluconazole
E. No effect on treatment occurs
Toxicity occurs due to increasing the levels of the “other” drug
Fluconazole is a associated with __?__
A. Liver failure, severe allergic reactions and arrhythmias.
B. Numerous drug interactions due to P450 inhibition
C. Fever, shaking, chills, hypotension, anorexia, nausea, vomiting, headache and tachypnea.
D. All the above
E. A & B only
A & B only
Pyrantel is a fairly potent NMJB. Why does Pyrantel kill pinworms in the GIT, but not the human who “owns” said GIT?
A. It is rapidly metabolized in people
B. Because it is so poorly absorbed
C. It is a Prodrug that must be activated
D. It is specific for invertebrates
E. Gastrointestinal bacteria break it down
Because it is so poorly absorbed
The half life of fluconazole is increased by \_\_?\_\_ A. Hydrochlorothiazide B. NSAIDs C. Warfarin D. Highly plasma protein bound drugs
Hydrochlorothiazide
What is a Pediculicide used for? A. To kill fungi B. To kill lice C. To kill bacteria D. To kill mites E. To kill worms
To kill lice
What is a Scabicide used for? A. To kill worms B. To kill lice C. To kill bacteria D. To kill fungi E. To kill mites
To kill mites
What is an Anthelmintic used for? A. To kill lice B. To kill bacteria C. To kill mites D. To kill fungi E. To kill worms
To kill worms
What is an antifungal used for? A. To kill fungi B. To kill mites C. To kill worms D. To kill bacteria E. To kill lice
To kill fungi
Which anthelmintic has an unknown mechanism of action? A. Pyrantel B. Praziquantel C. Ivermectin D. Albendazole E. Diethylcarbamazine
Praziquantel
`Which anthelmintic inhibits arachidonic acid metabolism in microfilaria? A. Ivermectin B. Praziquantel C. Pyrantel D. Albendazole E. Diethylcarbamazine
Diethylcarbamazine
Which anthelmintic is a NMJB (but, poorly absorbed in humans)? A. Albendazole B. Diethylcarbamazine C. Pyrantel D. Praziquantel E. Ivermectin
Pyrantel
Which antifungal is a highly specific P450 inhibitor available PO and IV? A. Clotrimazole B. Albendazole C. Praziquantel D. Fluconazole E. Amphotericin B
Fluconazole
Which antifungal is available OTC and by prescription for use as a topical treatment for ringworm and for candida infections? A. Amphotericin B B. Clotrimazole C. Fluconazole D. Praziquantel E. Albendazole
Clotrimazole
Which antifungal is only used IV and only against life threating fungal infections? A. Praziquantel B. Albendazole C. Amphotericin B D. Fluconazole E. Clotrimazole
Amphotericin B