(24) Viruses SLO Flashcards
A client is prescribed 5% Zovirax ointment to treat genital herpes. Which of these statements made by the client indicates you have been successful at teaching a very important concept related to acyclovir?
A. “Using this product will not prevent me from transmitting herpes to another person.”
B. “I will clean the infected area every other day with soap and water.”
C. “I will keep the area covered to prevent transmission of herpes to another person.”
D. “I will start applying the ointment as soon as the lesions crust over.”
E. All of the above are correct
“Using this product will not prevent me from transmitting herpes to another person.”
Interferon alfa 2 b is associated with __?__
A. Renal toxicity and seizures
B. Hemolytic anemia and fetotoxicity
C. Causing suicidal ideation and behavior, autoimmune and ischemic disorders and infections
D. Mitochondrial toxicity that leads to lactic acidosis
E. Body fat alterations and altered lipid metabolism
Causing suicidal ideation and behavior, autoimmune and ischemic disorders and infections
Lamivudine is prescribed to your client to treat chronic Hepatitis B. Your will teach your client to immediately report signs and symptoms of \_\_?\_\_ a potentially life-threating side effect of this drug that includes panting, shortness of breath, anxiety, and palpitations or rapid heart rate. A. Heart failure B. Liver failure C. Lactic acidosis D. Kidney failure E. Systemic yeast superinfection
Lactic acidosis
Protease Inhibitors are associated with __?__
A. Hemolytic anemia and fetotoxicity
B. Suicidal ideation, autoimmune and ischemic disorders and infections
C. Hypertriglyceridemia
D. Renal toxicity and seizures
E. Mitochondrial toxicity that leads to lactic acidosis
Hypertriglyceridemia
Ritonovir is used to increase the t ½ of \_\_?\_\_ A. Antibiotics like the penicillins B. All HIV medications C. Protease Inhibitors D. Reverse Transcriptase inhibitors E. Fusion Inhibitors
Protease Inhibitors
The acronym HAART means __?__
A. HIV Alternative Additional Retroviral Therapy
B. Highly Active Anti Retroviral Therapy
C. Hotly Argued Anti Retroviral Term
D. Highly Anticipated Advanced Retroviral Therapy
E. Hardly Appropriate Adult Review Themes
Highly Active Anti Retroviral Therapy
What does “Boosting “ mean with regards to HIV therapy?
A. Stealing drugs in order to get the amounts needed
B. Adding on additional amounts of drug, or increasing the frequency of dosing
C. Using one drug to increase the t ½ of another
D. Getting high off the anti retroviral drugs
E. Adding on additional drugs to the combination therapy
Using one drug to increase the t ½ of another
What is the antiviral mechanism of Acyclovir (Zovirax)?
A. It is a saturated fatty acid with unknown mechanism, OTC topical for oral and facial HSV
B. It is a fake nucleoside, once incorporated into viral DNA, it prevents elongation of DNA because the viral enzymes can’t fix the error. Used to treat Herpes simplex (HSV) and Varicella zoster (VZV – chicken pox).
C. It inhibits ion channel M2 protein in Influenza A virus; also NMDA antagonist and anticholinergic for EPS & PD
D. It inhibits neuraminidase preventing Influenza A infection (virus can’t enter cell)
E. It has an unknown mechanism and used topically to treat genital and perianal warts caused by the Human Papilloma Virus (HPV) and some skin cancers.
It is a fake nucleoside, once incorporated into viral DNA, it prevents elongation of DNA because the viral enzymes can’t fix the error. Used to treat Herpes simplex (HSV) and Varicella zoster (VZV – chicken pox).
What is the antiviral mechanism of Atazanavir (Reyataz)?
A. It is a Protease Inhibitor (PI) used in HAART for HIV and boosted with Ritonovir. PIs block viral particle assembly
B. It is a fake nucleoside used to treat CMV retinitis only
C. It is a Reverse Transcriptase Inhibitor (RTI) used in HAART for HIV
D. It is a fake nucleoside used to treat Herpes Simplex Virus (HSV) and Varicella.
E. It is a fake nucleoside. Used to treat Cytomegalovirus (CMV) and acyclovir resistant HSV
It is a Protease Inhibitor (PI) used in HAART for HIV and boosted with Ritonovir. PIs block viral particle assembly
What is the antiviral mechanism of Darunavir (Prezista)?
A. It is a fake nucleoside used to treat CMV retinitis only
B. It is a fake nucleoside used to treat Herpes Simplex Virus (HSV) and Varicella.
C. It is a Protease Inhibitor (PI) used in HAART for HIV and boosted with Ritonovir. PIs block viral particle assembly
D. It is a Reverse Transcriptase Inhibitor (RTI) used in HAART for HIV
E. It is a fake nucleoside. Used to treat Cytomegalovirus (CMV) and acyclovir resistant HSV
It is a Protease Inhibitor (PI) used in HAART for HIV and boosted with Ritonovir. PIs block viral particle assembly
What is the antiviral mechanism of Docosanol (Abreva)?
A. It is a saturated fatty acid with unknown mechanism, OTC topical for oral and facial HSV
B. It has an unknown mechanism and used topically to treat genital and perianal warts caused by the Human Papilloma Virus (HPV) and some skin cancers.
C. It inhibits ion channel M2 protein in Influenza A virus; also NMDA antagonist and anticholinergic for EPS & PD
D. It is a fake nucleoside, once incorporated into viral DNA, it prevents elongation of DNA because the viral enzymes can’t fix the error. Used to treat Herpes simplex (HSV) and Varicella zoster (VZV – chicken pox).
E. It inhibits neuraminidase preventing Influenza A infection (virus can’t enter cell)
It is a saturated fatty acid with unknown mechanism, OTC topical for oral and facial HSV
What is the antiviral mechanism of Efavirenz (Sustiva)?
A. It is a fake nucleoside. Used to treat Cytomegalovirus (CMV) and acyclovir resistant HSV
B. It is a Reverse Transcriptase Inhibitor (RTI) used in HAART for HIV
C. It is a fake nucleoside used to treat Herpes Simplex Virus (HSV) and Varicella.
D. It is a fake nucleoside used to treat CMV retinitis only
E. It is a Protease Inhibitor (PI) used in HAART for HIV and boosted with Ritonovir. PIs block viral particle assembly
It is a Reverse Transcriptase Inhibitor (RTI) used in HAART for HIV
What is the antiviral mechanism of Emtricitabine (Emtriva)?
A. It is a fake nucleoside used to treat Herpes Simplex Virus (HSV) and Varicella.
B. It is a fake nucleoside. Used to treat Cytomegalovirus (CMV) and acyclovir resistant HSV
C. It is a Reverse Transcriptase Inhibitor (RTI) used in HAART for HIV
D. It is a fake nucleoside used to treat CMV retinitis only
E. It is a Protease Inhibitor (PI) used in HAART for HIV and boosted with Ritonovir. PIs block viral particle assembly
It is a Reverse Transcriptase Inhibitor (RTI) used in HAART for HIV
What is the antiviral mechanism of Enfuviratide (Fuzeon)?
A. It blocks a cell surface receptor, called CCR5, used by HIV to enter cells
B. It is a Protease Inhibitor (PI) used in HAART for HIV and potent P450 inhibitor so it prolongs the t 1/2 of all the other PIs. Used in HIV HAART. PIs block viral particle assembly
C. Fusion inhibitor (FI) for HIV HAART.
D. It is a fake nucleoside. Used to treat Cytomegalovirus (CMV) and acyclovir resistant HSV
E. It is a Reverse Transcriptase Inhibitor (RTI) used in HAART for HIV
Fusion inhibitor (FI) for HIV HAART.
What is the antiviral mechanism of Fosamprenavir (Lexiva, Telzer)?
A. It is a fake nucleoside. Used to treat Cytomegalovirus (CMV) and acyclovir resistant HSV
B. It is a fake nucleoside used to treat Herpes Simplex Virus (HSV) and Varicella.
C. It is a fake nucleoside used to treat CMV retinitis only
D. It is a Reverse Transcriptase Inhibitor (RTI) used in HAART for HIV
E. It is a Protease Inhibitor (PI) used in HAART for HIV and boosted with Ritonovir. PIs block viral particle assembly
It is a Protease Inhibitor (PI) used in HAART for HIV and boosted with Ritonovir. PIs block viral particle assembly