(13) Endo 2 SLO Flashcards
A long-acting insulin, like Lantus is for __?__
A. Covering the whole day (24 hrs.), providing “basal” insulin and may be combined with another form
B. When the next meal is within 30-60 minutes of the injection
C. Taking with meals, often combined with longer acting form.
D. Over night use or for ½ of the day – often combined with another form
Covering the whole day (24 hrs.), providing “basal” insulin and may be combined with another form
A major consequence of insulin binding to its cell surface receptors on muscle and fat cells is the translocation of the GLUT-4 transporter from the cytosol to the cell surface, allowing \_\_?\_\_ to flow into the cell. A. Cholesterol B. Fatty acids C. Calcium D. Glucose E. Glycogen
Glucose
A number of drugs increase the risk of severe hypoglycemia when given with sulfonylureas. Which of the following should be avoided or used with great caution by patients taking a sulfonylurea?
A. NSAIDs and salicylates in large doses
B. Sulfonamides including thiazide diuretics
C. Coumarins (e.g., warfarin)
D. beta blockers
E. All the above
All the above
A Rapid-acting insulin , like Humalog is for __?__.
A. When the next meal is within 30-60 minutes of the injection
B. Covering the whole day (24 hrs.) and may be combined with another form
C. Taking with meals, often combined with longer acting form.
D. Over night use or for ½ of the day – often combined with another form
Taking with meals, often combined with longer acting form.
A short-acting insulin, like Humulin is for __?__
A. Over night use or for ½ of the day – often combined with another form
B. When the next meal is within 30-60 minutes of the injection
C. Covering the whole day (24 hrs.) and may be combined with another form
D. Taking with meals, often combined with longer acting form.
When the next meal is within 30-60 minutes of the injection
A type of diabetes that has mixed DMT1 & DMT2 characteristics is associated with \_\_?\_\_. A. Cystic fibrosis B. Diabetes insipidus C. Gestational diabetes D. Diabetes mellitus type 1 E. Diabetes mellitus type 2
Cystic fibrosis
Acarbose (Precose) inhibits a glucosidase, which means it acts to reduce blood glucose by __?__
A. Preventing the breakdown of incretins
B. Preventing the digestion and absorption of carbohydrates
C. Blocking hepatic gluconeogenesis
D. Stimulating the pancreas to release more insulin
E. Mimicking incretins
Preventing the digestion and absorption of carbohydrates
Acarbose (Precose) is a(n) __?__ antihyperglycemic drug used as an adjunct to diet and exercise to treat __?__.
A. Oral /Diabetes insipidus
B. Parenteral /DMT1
C. Oral /DMT 1 and DMT 2
D. Parenteral/Hypoglycemia
E. Parenteral /DMT1 and some cases of DMT2
Oral /DMT 1 and DMT 2
Alpha glucosidase inhibitors like \_\_?\_\_ are associated with gas. A. Insulin B. Metformin C. Liraglutide D. Glucagon E. Acarbose
Acarbose
An Intermediate-acting insulin, like NPH is for __?_
A. Taking with meals, often combined with longer acting form.
B. Covering the whole day (24 hrs.) & may be combined with another form
C. Over night use or for ½ of the day – often combined with another form
D. When the next meal is within 30-60 minutes of the injection
Over night use or for ½ of the day – often combined with another form
Bromocriptine given in very low doses first thing in the morning is indicated to help provide glycemic control in DMT2 patients along with diet and exercise. This product is called\_\_?\_\_ A. Cycloset B. Parlodel C. Navane D. Stalevo E. L-Dopa
Cycloset
Chlorpropamide (Diabinese) is a 1st generation sulfonylurea, which makes it a secretagogue. What does secretagogue mean?
A. It prevents the pancreas from releasing insulin
B. It inhibits secreted insulin from binding to its receptor
C. It causes muscle and fat cells to secrete insulin
D. It stimulates the pancreas to secrete glucagon
E. It stimulates the pancreas to secrete insulin
It stimulates the pancreas to secrete insulin
Chlorpropamide (Diabinese) is a(n) __?__ antihyperglycemic drug used as an adjunct to diet and exercise to treat __?__.
A. Oral /DMT2
B. Oral /Diabetes insipidus
C. Oral /DMT1
D. None of the given answers is correct
E. Parenteral /DMT1 and some cases of DMT2
Oral /DMT2
Exogenous \_\_?\_\_ is associated with the release of catecholamines. A. DDP4 inhibitors B. Glucagon C. Insulin D. GLP-1 agonists E. Acarbose
Glucagon
Glucagon (Glucagen) is a(n) \_\_?\_\_ drug used to treat \_\_?\_\_. A. Parenteral/Hypoglycemia B. Parenteral/Hyperglycemia C. Parenteral/Diabetes insipidus D. Oral /DMT1 E. Oral/DMT2
Parenteral/Hypoglycemia
Glucagon (Glucagen) replaces a naturally occurring hormone that acts to __?__
A. Stimulate fatty acid synthesis
B. Increase glucose uptake by muscle and fat cells
C. Increase insulin sensitivity
D. Elevate blood glucose levels
E. Reduce blood glucose levels
Elevate blood glucose levels
Glyburide (Micronase) is a 2nd generation sulfonylurea which means you must have a functioning \_\_?\_\_. A. Kidney B. Lung C. Pancreas D. Liver E. Gall bladder
Pancreas