(6)Autocoid SLO Flashcards
1st generation antihistamines, like diphenhydramine, are associated with __?__.
A. Dry eyes, mouth, throat and an inability to sweat (easily over heated)
B. Urinary retention
C. Sedation
D. Antimuscarinic effects
E. All of the above
Dry eyes, mouth, throat and an inability to sweat (easily over heated), urinary retention, sedation, antimuscarinic effects - ALL
A drug name ends in “pril,” what is the drug class? A. LOX inhibitor B. ACEI C. LT Receptor blocker D. NSAID E. ARB
ACEI
A drug name ends in “sartan,” what is the drug class? A. NSAID B. ACEI C. Anticholinergic D. ARB E. LOX inhibitor
ARB
A meal high in fat can substantially reduce the absorption of \_\_?\_\_. A. Ibuprofen B. Diphenhydramine C. Promethazine D. Benazepril E. Aliskiren
Aliskiren (Tekturna)
ACEI are associated with \_\_?\_\_. A. Ibuprofen B. Diphenhydramine C. Promethazine D. Benazepril E. Aliskiren
Angioedema, fetotoxicity in the 2nd and 3rd trimester, acute renal failure, potassium retention (Hyperkalemia) - ALL
ARBs are associated with \_\_?\_\_. A. Sedation B. Fetotoxicity in the 2nd and 3rd trimester C. Diarrhea, nausea D. Hyperkalemia E. B, C and D only
Fetotoxicity in the 2nd and 3rd trimester, Diarrhea, nausea, Hyperkalemia NOT SEDATION
Corticosteroids are associated with \_\_?\_\_. A. Gastric ulcers B. Sedation C. Antimuscarinic effects D. Angioedema E. Cataracts
Cataracts
H2 ANTagonists are known as \_\_?\_\_ A. Gastric acid reducers B. Antidepressants C. Antihistamines D. Antihypertensives E. Anti Migraine
Gastric acid reducers
Loratadine has a long half-life, therefore it is administered less frequently than 1st generation antihistamines like \_\_?\_\_ A. Buspirone B. Valsartan C. Fluoxetine D. Azelastine E. Diphenhydramine
Diphenhydramine (Benadryl)
Misoprostol will cause \_\_?\_\_ A. Abortion in pregnant woman B. Severe tissue injury regardless of administration route C. Fatal respiratory depression in kids D. Suicide E. 1st dose anaphylaxis
Abortion in pregnant women
NSAIDs are associated with \_\_?\_\_ A. Dry mouth, dry eyes B. Gastric ulcers C. Myalgia D. Sedation E. Cataracts
Gastric Ulcers
Patients already on a diuretic, who are then given an ACEI, may experience severe: A. Hyperkalemia B. Hypotension C. Hepatotoxicity D. Dysgeusia E. Neutropenia
Hypotension
Renin-Angiotensin-Aldosterone pathways control BP. Renin is released from kidney juxtaglomerular epithelial cells in response to __?__
A. Decreased NaCl to kidney
B. All of the listed answers are correct
C. Decreased blood pressure
D. Decreased intra renal pressure
E. Sympathetic (beta 1) stimulation.
Decreased blood pressure, Decreased NaCl to kidney Decreased intra renal pressure Sympathetic (beta 1) stimulation. **ALL**
Serotonergic drugs (agonists) are incompatible with \_\_?\_\_ A. MAOIs B. ACEIs C. DRIs D. NSAIDs E. ARBs
MAOIs
Which is a 1st generation antihistamine OTC used PO and IV/IM for the treatment of most allergic reactions including anaphylaxis (along with epinephrine); motion sickness; and as an anti-Parkinsonism and anti-extrapyramidal symptoms (EPS) drug. It is usually given PO QID, but no more than q4h and given no more than q6h IV/IM. A. Chlorpheniramine B. Fexofenadine C. Azelastine D. Diphenhydramine E. Loratadine
Diphenhydramine (Benadryl)
Which is a 2nd generation antihistamine used SID PO to treat symptoms of allergic rhinitis? A. Promethazine B. Ondansetron C. Diphenhydramine D. Loratadine E. Chlorpheniramine
Loratadine (Claritin)
Which is a 2nd generation antihistamine used to relieve symptoms of seasonal allergic rhinitis and to treat idiopathic urticaria. It is given PO SID or BID A. Chlorpheniramine B. Fluoxetine C. Promethazine D. Fexofenadine E. Diphenhydramine
Fexofenadine (Allegra)
Which is a 5-PDE inhibitor used PO to treat erectile dysfunction? It is also used to treat pulmonary arterial hypertension. A. Zileuton B. Montelukast C. Enalapril D. Sildenafil E. Aprotinin
Sildenafil (Viagra, Revitio)
Which is a direct renin inhibitor (DRI)? A. Misoprostol B. Montelukast C. Aliskiren D. Fluoxetine E. Buspirone
Aliskiren (Tekturna)
Which is a Leukotriene (LT) Receptor blocker given PO SID in the evening for asthma and at any time of day for allergic rhinitis? A. Misoprostol B. Captopril C. Diphenhydramine D. Dexamethasone E. Montelukast
Montelukast (Singulair)
Which is a LT receptor blocker for asthma, given PO SID an hour before or 2 hours after a meal? A. Zileuton B. Benazepril C. Fexofenadine D. Ibuprofen E. Zafirlukast
Zafirlukast (Accolate)
Which is a natural proteinase inhibitor obtained from bovine lung? Used IV only to reduce blood loss during cardiac surgery. A. Zileuton B. Aprotinin C. Sildenafil D. Buspirone E. Montelukast
Aprotinin (Trasylol)
Which is a Prostaglandin E (PGE) analog used to reduce the risk of NSAID induced gastric ulcers? It is given PO QID with food. A. Buspirone B. Fluoxetine C. Montelukast D. Aliskiren E. Misoprostol
Misoprostol (Cytotech)
Which is Vasotec given PO SID to treat HT and left ventricular dysfunction after MI. A. Irbesartan B. Enalapril C. Valsartan D. Benazepril E. Captopril
Enalapril
Which is a 1st generation antihistamine OTC used PO q4h-q6h for the temporary relief of respiratory allergy and cold symptoms. A. Trazodone B. Fexofenadine C. Loratadine D. Azelastine E. Chlorpheniramine
Chlorpheniramine (Chlor-Trimeton)
Which is a 2nd generation antihistamine used as a metered nasal spray and as ophthalmic drops to relieve the symptoms of allergic rhinitis? A. Azelastine B. Promethazine C. Diphenhydramine D. Benadryl E. Sumatriptan
Azelastine (Astelin, Optivar)
Which is a 5-lipoxygenase (LOX) inhibitor given PO QID for asthma? A. Zafirlukast B. Zileuton C. Diphenhydramine D. Irbesartan E. Loratadine
Zileuton (Zyflo)
Which is an ACEI given PO SID to treat HT? A. Benazepril B. Trazodone C. Aprotinin D. Irbesartan E. Aliskiren
Benazepril (Lotensin)
