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Pharmacology > (6)Autocoid SLO > Flashcards

(6)Autocoid SLO Flashcards

1
Q

1st generation antihistamines, like diphenhydramine, are associated with __?__.
A. Dry eyes, mouth, throat and an inability to sweat (easily over heated)
B. Urinary retention
C. Sedation
D. Antimuscarinic effects
E. All of the above

A

Dry eyes, mouth, throat and an inability to sweat (easily over heated), urinary retention, sedation, antimuscarinic effects - ALL

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2
Q 
A drug name ends in “pril,” what is the drug class?
A. 	LOX inhibitor
B. 	ACEI
C. 	LT Receptor blocker
D. 	NSAID
E. 	ARB
A

ACEI

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3
Q 
A drug name ends in “sartan,” what is the drug class?
A. 	NSAID
B. 	ACEI
C. 	Anticholinergic
D. 	ARB
E. 	LOX inhibitor
A

ARB

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4
Q 
A meal high in fat can substantially reduce the absorption of \_\_?\_\_.
A. 	Ibuprofen
B. 	Diphenhydramine
C. 	Promethazine
D. 	Benazepril
E. 	Aliskiren
A

Aliskiren (Tekturna)

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5
Q 
ACEI are associated with \_\_?\_\_.
A. 	Ibuprofen
B. 	Diphenhydramine
C. 	Promethazine
D. 	Benazepril
E. 	Aliskiren
A

Angioedema, fetotoxicity in the 2nd and 3rd trimester, acute renal failure, potassium retention (Hyperkalemia) - ALL

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6
Q 
ARBs are associated with \_\_?\_\_.
A. 	Sedation
B. 	Fetotoxicity in the 2nd and 3rd trimester
C. 	Diarrhea, nausea
D. 	Hyperkalemia
E. 	B, C and D only
A

Fetotoxicity in the 2nd and 3rd trimester, Diarrhea, nausea, Hyperkalemia NOT SEDATION

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7
Q 
Corticosteroids are associated with \_\_?\_\_.
A. 	Gastric ulcers
B. 	Sedation
C. 	Antimuscarinic effects
D. 	Angioedema
E. 	Cataracts
A

Cataracts

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8
Q 
H2 ANTagonists are known as \_\_?\_\_
A. 	Gastric acid reducers
B. 	Antidepressants
C. 	Antihistamines
D. 	Antihypertensives
E. 	Anti Migraine
A

Gastric acid reducers

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9
Q 
Loratadine has a long half-life, therefore it is administered less frequently than 1st generation antihistamines like \_\_?\_\_
A. 	Buspirone
B. 	Valsartan
C. 	Fluoxetine
D. 	Azelastine
E. 	Diphenhydramine
A

Diphenhydramine (Benadryl)

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10
Q 
Misoprostol will cause \_\_?\_\_
A. 	Abortion in pregnant woman
B. 	Severe tissue injury regardless of administration route
C. 	Fatal respiratory depression in kids
D. 	Suicide
E. 	1st dose anaphylaxis
A

Abortion in pregnant women

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11
Q 
NSAIDs are associated with \_\_?\_\_
A. 	Dry mouth, dry eyes
B. 	Gastric ulcers
C. 	Myalgia
D. 	Sedation
E. 	Cataracts
A

Gastric Ulcers

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12
Q 
Patients already on a diuretic, who are then given an ACEI, may experience severe:
A. 	Hyperkalemia
B. 	Hypotension
C. 	Hepatotoxicity
D. 	Dysgeusia
E. 	Neutropenia
A

Hypotension

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13
Q

Renin-Angiotensin-Aldosterone pathways control BP. Renin is released from kidney juxtaglomerular epithelial cells in response to __?__
A. Decreased NaCl to kidney
B. All of the listed answers are correct
C. Decreased blood pressure
D. Decreased intra renal pressure
E. Sympathetic (beta 1) stimulation.

A 
Decreased blood pressure, 
Decreased NaCl to kidney
Decreased intra renal pressure
Sympathetic (beta 1) stimulation.
**ALL**
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14
Q 
Serotonergic drugs (agonists) are incompatible with \_\_?\_\_
A. 	MAOIs
B. 	ACEIs
C. 	DRIs
D. 	NSAIDs
E. 	ARBs
A

MAOIs

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15
Q 
Which is a 1st generation antihistamine OTC used PO and IV/IM for the treatment of most allergic reactions including anaphylaxis (along with epinephrine); motion sickness; and as an anti-Parkinsonism and anti-extrapyramidal symptoms (EPS) drug.  It is usually given PO QID, but no more than q4h and given no more than q6h IV/IM.
A. 	Chlorpheniramine
B. 	Fexofenadine
C. 	Azelastine
D. 	Diphenhydramine
E. 	Loratadine
A

Diphenhydramine (Benadryl)

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16
Q 
Which is a 2nd generation antihistamine used SID PO to treat symptoms of allergic rhinitis?
A. 	Promethazine
B. 	Ondansetron
C. 	Diphenhydramine
D. 	Loratadine
E. 	Chlorpheniramine
A

Loratadine (Claritin)

17
Q 
Which is a 2nd generation antihistamine used to relieve symptoms of seasonal allergic rhinitis and to treat idiopathic urticaria.  It is given PO SID or BID
A. 	Chlorpheniramine
B. 	Fluoxetine
C. 	Promethazine
D. 	Fexofenadine
E. 	Diphenhydramine
A

Fexofenadine (Allegra)

18
Q 
Which is a 5-PDE inhibitor used PO to treat erectile dysfunction?  It is also used to treat pulmonary arterial hypertension.
A. 	Zileuton
B. 	Montelukast
C. 	Enalapril
D. 	Sildenafil
E. 	Aprotinin
A

Sildenafil (Viagra, Revitio)

19
Q 
Which is a direct renin inhibitor (DRI)?
A. 	Misoprostol
B. 	Montelukast
C. 	Aliskiren
D. 	Fluoxetine
E. 	Buspirone
A

Aliskiren (Tekturna)

20
Q 
Which is a Leukotriene (LT) Receptor blocker given PO SID in the evening for asthma and at any time of day for allergic rhinitis?
A. 	Misoprostol
B. 	Captopril
C. 	Diphenhydramine
D. 	Dexamethasone
E. 	Montelukast
A

Montelukast (Singulair)

21
Q 
Which is a LT receptor blocker for asthma, given PO SID an hour before or 2 hours after a meal?
A. 	Zileuton
B. 	Benazepril
C. 	Fexofenadine
D. 	Ibuprofen
E. 	Zafirlukast
A

Zafirlukast (Accolate)

22
Q 
Which is a natural proteinase inhibitor obtained from bovine lung?  Used IV only to reduce blood loss during cardiac surgery.
A. 	Zileuton
B. 	Aprotinin
C. 	Sildenafil
D. 	Buspirone
E. 	Montelukast
A

Aprotinin (Trasylol)

23
Q 
Which is a Prostaglandin E (PGE) analog used to reduce the risk of NSAID induced gastric ulcers?  It is given PO QID with food.
A. 	Buspirone
B. 	Fluoxetine
C. 	Montelukast
D. 	Aliskiren
E. 	Misoprostol
A

Misoprostol (Cytotech)

24
Q 
Which is Vasotec given PO SID to treat HT and left ventricular dysfunction after MI.
A. 	Irbesartan
B. 	Enalapril
C. 	Valsartan
D. 	Benazepril
E. 	Captopril
A

Enalapril

25
Q 
Which  is a 1st generation antihistamine OTC used PO q4h-q6h for the temporary relief of respiratory allergy and cold symptoms.
A. 	Trazodone
B. 	Fexofenadine
C. 	Loratadine
D. 	Azelastine
E. 	Chlorpheniramine
A

Chlorpheniramine (Chlor-Trimeton)

26
Q 
Which is a 2nd generation antihistamine used as a metered nasal spray and as ophthalmic drops to relieve the symptoms of allergic rhinitis?
A. 	Azelastine
B. 	Promethazine
C. 	Diphenhydramine
D. 	Benadryl
E. 	Sumatriptan
A

Azelastine (Astelin, Optivar)

27
Q 
Which is a 5-lipoxygenase (LOX) inhibitor given PO QID for asthma?
A. 	Zafirlukast
B. 	Zileuton
C. 	Diphenhydramine
D. 	Irbesartan
E. 	Loratadine
A

Zileuton (Zyflo)

28
Q 
Which is an ACEI given PO SID to treat HT?
A. 	Benazepril
B. 	Trazodone
C. 	Aprotinin
D. 	Irbesartan
E. 	Aliskiren
A

Benazepril (Lotensin)

Pharmacology (30 decks)

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