68. Pathologic pigmentation caused by porphyrins

Question 1

CEP: Congenital Erythropietic Porphyrin

Answer 1

• Brown-violet
• fuoresence under UV light
• causes: pink teath “ in cat, calf, piglets

Question 2

Porphyrin as a component of Hemoglobin

Answer 2

Protoporphyrin + Fe(iron) + globulin = Hb

Question 3

Where is porphyrin synthesised?

Answer 3

Liver & Bone marrow

Question 4

Porphyrin excretion

Answer 4

Excreted with urine & faeces:

• Uroporphyrin
• Coproporphyrin

Question 5

Characteristics of porphyria

Answer 5

• Spongy bones are coloured
• Dental cement –> brown
• Dentin–> pink, reddish brown
• Enamel–> White
• Cartilage, ligaments & tendons–»Uncoloured