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Pathology C topics > 67. Pathologic pigmentation caused by hematoidin, and bilirubin > Flashcards

67. Pathologic pigmentation caused by hematoidin, and bilirubin Flashcards

1
Q

Hematoidin

A
  • Brownish pigment
  • Old haemorrhages
  • Iron free derivate of haem
  • Spontaneously formed
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2
Q

Bilirubin

A

Yellow-ish brown pigment formed during the breakdown of heme

  • Bile pigment
  • Biliverdin: Oxidised
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3
Q

Jaundice/Icterus

A
  • Bilrubin in the tissues
  • Staining the tissues yellow : Conjunctiva, sclera, intima of blood vessels
  • Bird liver: Green (Biliverdin)
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4
Q

Jaundice / icterus –> Staining

A

Forsgren (Reddish blue)

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5
Q

3 types of jaundice/icterus:

A

Hepatic, , Prehepatic, Posthepatic

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6
Q

Posthepatic jaundice

A

Obstruction of bile duct
BrII can be found in the blood and urine

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7
Q

Prehepatic jaundice

A
  • Br-I : in blood
  • Intensive haemolysis
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8
Q

Hepatic icterus

A

Toxic or retention

  • Bilirubin I & II in the blood
  • In the urine: Br-II & UBG
  • Associated with liver damage, and necrosis of
    hepatocytes
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9
Q

Example of what could lead to posthepatic icterus

A

Cholelithiasis
Pancreatitis
Neiplasia

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Pathology C topics (29 decks)

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