64. Pathological mucus production and pathological changes in the mucosubstance

Question 1

Pathological Mucus Production

Cause + Composition

Answer 1

Cause: Often linked to carbohydrate metabolism disorders.

Composition: Mucopolysaccharides + proteins

Question 2

Mucus of Epithelial Origin

Physiological Role

Answer 2

→ Protective and lubricating function of
mucous membranes

• Mucous glands
• Goblet cells

Question 3

Mucus of Epithelial Origin

Pathological

Answer 3

Hypersecretion:
* Mucocele→ Mucus accumulation, outlet obstruction.
* Mucinous tumors → Increased production.
* Equine RAO

Infection Response:
* Swine dysentery → Mucus overstimulation → Necrotic mucosa.

Mucoid enteropathy→ Intestinal imbalance.

Question 4

Mucus of Connective Tissue Origin

Normal Locations:

Answer 4

• ECM
• umbilical cord
• estrus.

Question 5

Mucus of Connective Tissue Origin

Pathological Changes:

Answer 5

Increased Production:
* Hypothyroidism → Hyaluronic acid accumulation → Myxedema.

• Hyperestrogenism (e.g., mycotoxin
  related) → Estrogen syndrome in piglets.
• Shar-Pei Mucinosis → Excess mucin in skin.

Decreased Degradation:
* Mucopolysaccharidoses (MPS)→ Mucus accumulation.

• Myxomatosis (rabbits)→ Tumor-like nodules.