560F Additional Info Flashcards
What is the optimal dosage of gamma and delta tocotrienols to reduce serum lipids?
500 mg
125 mg
750 mg
250 mg
250mg
What energy nutrient is essential for a client with congestive heart failure?
Pantothenic Acid
Riboflavin
Glutamine
CoQ10
CoQ10
What amino acid will enhance the anti-hypertensive effects of magnesium?
Histidine
Glycine
Taurine
Glutamine
Taurine
Which two amino acids have been shown to lower high blood pressure?
Aspartate and Arginine
Arginine and Taurine
Glutamine and Glycine
Glycine and Taurine
Arginine and Taurine
What would not be the appropriate follow up test for a macrocytic anemia?
Methylmalonic acid
Ferritin
Vitamin B12
Folate
Ferritin
A vegetarian with congestive heart failure is most likely deficient in which nutrient?
Arginine
Omega 3 fatty acids
Folate
Carnitine
Carnitine
Which of the following about lipoproteins is not significantly affected by diet and exercise?
HDL
LDL particle size
Lipoprotein (a)
Apolipoprotein B
Lp(a)
Which cooking method will produce the lease AGEs in one’s diet?
Boil
Broil
Grill
Fry
Boil
Which botanical is an analog to metformin?
Berberine
Bitter melon
Cinnamon
Fenugreek
Berberine
Which vegetable juice has natural anti-HTN properties and acts as a vasodilator and a diuretic?
Cabbage
Celery
Watercress
Asparagus
Celery
Which botanical contains a constituent called apigenin, which binds to central benzodiazepine receptors causing anti-anxiolytic effects?
Berberine
Passionflower
Rhodiola
Bitter Melon
Passionflower
A client presents to your office with hypertension. He is currently on a beta-blocker and taking magnesium. He has a diet relatively high in sodium. What additional nutrient would you suggest may help?
Choline
Potassium
Vitamin B6
Vitamin C
Potassium
Which nutrient is necessary for angiogenesis?
Zinc
Copper
Selenium
Argon
Copper
What nutrient recommendation would not be suggested for a client with congestive heart failure?
Increased potassium
Decreased potassium
Decreased potassium
Which vitamin plays a role in autoimmunity by its impact on balancing TH1 and TH2?
A
E
D
K
D
Which is not true of Metformin?
Decreases homocysteine levels
Decreases folate
Decreases vitamin B12
Increases homocysteine
Decreases homocysteine levels
Which is not true about artificial sweeteners (ie. Sucralose)?
Increases the abundance and diversity of the
beneficial bacteria in the GI tract
Alters insulin
Induce glucose intolerance
Alters glucagon-like peptide 1 (GLP-1) level
Increases the abundance and diversity of the
beneficial bacteria in the GI tract
What nutrient has been shown to increase insulin sensitivity by 20-30%?
Alpha Lipoic Acid
Vitamin B12
Carnitine
CoQ10
Alpha lipoic acid
What fasting blood glucose is diagnostic of type II diabetes?
130 mg/dl
105 mg/dl
125 mg/dl
110 mg/dl
130 (technically anything above 126)
Small Intestinal Bacterial Overgrowth (SIBO) occurs in approximately what percent of IBS individuals?
10%
30%
50%
60%
10%
Which nutrient can bind to a T-cell receptor and dampen the immune response?
Zinc carnosine
Quercetin
N-acetyl-cysteine
N-acetyl-glucosamine
N-acetyl-glucosamine
What stool marker would be the most effective for monitoring disease activity in Inflammatory Bowel Disease?
SIgA
Hs-CRP
EPX
Calprotectin
Calprotectin
According to a 2012 study in the Journal of Immunology, at what vitamin D level was the highest degree of inflammatory inhibition seen?
70 ng/ml
50 ng/ml
30 ng/ml
15 ng/ml
50ng/ml
What bacteria is associated with ulceration?
H. pylori
Proteus mirabilus
E. coli
Klebsiella pneumoniae
H Pylori
Which is not one of the Rome III criteria for irritable bowel disease?
Onset associated with a change in form or appearance of stool
Improvement with defecation
Onset associated with a change in frequency of stool
Changes between constipation and diarrhea for at least 3 months
Changes between constipation and diarrhea for at least 3 months
Atopic dermatitis is associated with what immunoglobulin?
IgG
IgM
IgA
IgE
IgE
What nutrient significantly inhibits carbohydrate-mediated tumor growth, angiogenesis, and metastasis by its effects on Galectin 3 proteins?
Modified Citrus Pectin
Quercetin
Curcumin
EGCg
Modified Citrus Pectin
What tocotrienol isomer has demonstrated the significant cytotoxic effect on human cancer cells?
Alpha
Beta
Gamma
Delta
Gamma
What form of Vitamin B3 has been used as a therapy for the osteoarthritis?
Niacinamide
Nicotinic acid
Niacinamide
Which is not a mechanism of action of vitamin C for osteoarthritis?
Analgesic
Decrease collagen degradation
Increase collagen synthesis
Increase proteoglycan synthesis
Analgesic
Which nutrient’s mechanism of actions is as an analgesic for osteoarthritis?
Vitamin C
Fish Oil
SAMe
SAMe
The following labs are elevated in which type of anemia? MMA, MCV, MCH, RDW
B12 deficiency anemia
Folate deficiency anemia
IDA
B12
The following labs are elevated in which type of anemia? FIGLU, MCV, MCH, RDW
B12 deficiency anemia
Folate deficiency anemia
IDA
folate
Macrocytic and normochromic describes….
B12 deficiency anemia
Folate deficiency anemia
IDA
Both b12 and folate
Both B12 and folate
The following labs are elevated in which type of anemia? RDW, TIBC
B12 deficiency anemia
Folate deficiency anemia
IDA
IDA
The following labs are low in which type of anemia? Hct, Hgb, MCV, MCH, Ferritin, Transferrin
B12 deficiency anemia
Folate deficiency anemia
IDA
IDA
Microcytic and hypochromic =
B12 deficiency anemia
Folate deficiency anemia
IDA
IDA
HTN is caused by oxidative stress, inflammation, and autoimmune vascular dysfunction.
T/F
T
Ferritin can be elevated during inflammation because it is also an acute phase reactant.
T/F
True
Can Cadmium and Lead contribute to HTN?
Yes
Which nutrient is a vasodilator, and central alpha agonist and can lower HTN?
Sodium
Potassium
Mg
Selenium
Potassium
Which nutrient is a central alpha agonist and low levels can cause HTN (dose is rec’d at 50mg/day)?
Potassium
Magnesium
Zinc
Copper
Zinc
4-10 grams per day helps to stabilize normal BP due to its effect on NO synthesis.
Arginine
Taurine
Magnesium
Argninine
Which amino acid can be a good adjunct to arginine in the tx of HTN?
Taurine
Lysine
Citrulline
Ornithine
Citrulline
Which botanical has ACE inhibitor, beta-blocker, calcium channel blocker and diuretic actions?
Hawthorn
Garlic
Berberine
Bitter Melon
Hawthorn
Which botanical increases bradykinin and NO to help reduce HTN?
Hawthorn
Garlic
Berberine
Bitter Melon
Garlic
Dietary cholesterol intake does not alter serum cholesterol significantly.
T/F
True
Increased refined CHO intake has no impact on lipids.
T/F
False, great impact
Soluble fiber has a beneficial effect on dyslipidemia
T/F
T
Monounsaturated fats like EVOO should be avoided with dyslipidemia
T/F
FALSE…..should add to foods, will help reverse the dyslipidemia
Plant sterols at 2-3 grams per day can help dyslipidemia.
T/F
True
Which of these can be beneficial for tx of dyslipidemia?
Citrus Bergamont EGCg Curcumin NAC Niacin Pantethine RYR Tocotrienols All of the above?
ALL of the above
In addition to carnitine and magnesium, which other nutrient(s) would help with CHF?
CoQ10
D-Ribose
Garlic
RYR
CoQ10 and D-Ribose
Which drug has the following DNDs? Zinc, sodium
ACE Inhibitors
Anti-diabetics
Antibiotics
ACE inhibitors
Which drug has the following DNDs? CoQ10, B12 , B9
ACE Inhibitors
Anti-diabetics
Antibiotics
Anti-diabetics
Antibiotics deplete B-vitamins, vit K.
T/F
True
IBS dx requires adherence to Rome III criteria: at least 3 months, with onset at least 6 months previously of recurrent abdominal pain/discomfort associated with:
Improvement with defecation
Onset associated with change in stool frequency
Onset associated with change in stool appearance
Two or more of the above
Two or more
95% of serotonin is in the gut
T/F
T
Serotonin affects IBS due to its involvement with visceral hypersensitivity.
T/F
T
Which form of IBS has low serotonin usually associated with it?
IBS - D
IBS -C
IBS- M
IBS C
Which form of IBS has high serotonin usually associated with it?
IBS - D
IBS -C
IBS- M
IBS-D
Celiac confirmation requires a small bowel biopsy.
T/F
True
Which are large molecules associated with gram negative bacteria that are also endotoxins? They are a sign of permeability/dysbiosis
Zonulin
Occludin
Lipopolysaccharides
Lipopolysaccharides (remember Dr Penn’s comment “little pieces of shit”)
Which protein regulates intestinal permeability, and high levels are signs of increased permeability?
Occludin
Zonulin
Glutamine
Zonulin
Which protein holds the tight junctions together and are damaged by autoantibodies, leading to the breakdown of the junctions?
Occludin
Zonulin
sIgA
mucin
Occludin
What are the 4 R’s?
Remove
Replace
Reinoculate
Repair
A fasting glucose between 100-125 mg/dl is considered?
Type 1 diabetic
Type 2 diabetic
Pre-diabetic
Normal
Pre-diabetic
HbA1c between 5.7%-6.4% is….
Type 1 diabetic
Type 2 diabetic
Pre-diabetic
Normal
Pre-diabetic
Gymnema, fenugreek, bitter melon, and berberine are botanicals that can be used to treat which condition?
Asthma
Arthritis
Type 2 DM
Adrenal Fatigue
Type 2 DM
Which condition stems from long term hyperglycemia that caused increased synthesis of FAs and TGs in liver? Sx include fatigue, URQ abdominal pain.
PCOS
Gallstones
Kidney Stones
NASH/NAFLD
NASH/NAFLD
With kidney stones, diet should be individualized to blood type.
T/F
False….it should be based on STONE type
Met Syndrome requires how many of the following criteria for dx to be present at the same time in MEN?
Waist Circum above 40 TGs > 150 HDL < 40 BP > 130/85 Fasting glucose >100
ALL of them
2
3
3 need to be present
Which Met Syn criteria are different for women than men?
Waist Circumference TGs HDL BP Fasting glucose
WC for women is >35 compared to >40 for men
HDL for women is <50 compared to < 40 for men
Persistent proteinuria and microalbuminuria indicate…
Kidney stones
Kidney disease
Liver disease
Gallstones
Kidney disease
Which kidney stones develop in acidic urine?
Calcium Oxalate
Calcium Phosphate
Struvite
All of these
Oxalate
Which kidney stones develop in alkaline urine?
Calcium Oxalate Calcium Phosphate Struvite All of these Both phosphate and struvite
Both phosphate and struvite
Which kidney stones require increased pH and supplementation with potassium citrate or bicarbonate for tx?
Calcium Oxalate
Calcium Phosphate
Struvite
All of these
OXalate
Which stones would require pH to be lowered with ammonium sulfate or high acidic diets?
Calcium Oxalate
Calcium Phosphate
Struvite
All of these
Phosphate and struvite
The SHINE protocol stands for SLEEP, HORMONAL DYSFUNCTION, INFECTIONS, OPTIMIZING NUTRITION, and EXERCISE. This is for treating which condition?
Restless leg syndrome
PCOS
Adrenal fatigue
Fibromyalgia
Fibromyalgia
Which minerals are often low in Restless leg syndrome?
(there are 2)
Calcium Magnesium Potassium Iron Zinc
Mg and Fe
Butterbur, B2, Alpha lipoic, Feverfew and Mg can be used to treat:
PCOS
Migraines
Osteoarthritis
RLS
Migraines
How much B2 for migraines?
200-400mg/d
100-300 mg/d
400-600mg/d
200-400mg/d
Which botanical down regulates eNOS and iNOS as its mechanism for migraine therapy?
Butterbur
Feverfew
Feverfew
Which type of Magnesium is best for migraines?
Mg Oxide Mg Malate Mg Citrate Mg Taurate Mg Threonate
MG Threonate
How much Taurine is useful for Hypertension (when used with Mg)?
500mg/d
1000-2000mg/d
2000-3000mg/d
4000mg/d
1000-2000mg/d
GABA is the major __________ neurotransmitter
Excitatory
Calming
calming
IgA tissue transaminase antibodies (tTGA) are the most sensitive for celiac
T/F
True
IgA endomysial antibodies are not confirmatory of celiac when tTGA are positive.
T/F
False, they are confirmatory
If a patient is IgA deficiency, which test can be used for detecting celiac instead of IgA tTGA?
IgG tTGA
IgG DGP-AGA
Both
Neither
Both IgG tGA and IgG DGP-AGA
IgA AGA (anti-gliadin antibodies) are useful for dx of :
Celiac
Non-Celiac gluten sensitivity
Neither
Non-celiac gluten sensitivity
IgG DGP-AGA (deamidated gliadin peptides) are very highly specific for Celiac Disease
T/F
True
LDH is a lab test to measure…
Tissue breakdown
Inflammation
Lactic acidosis
Tissue breakdown
CK (creatine kinase) indicates breakdown of which tissues?
Muscle
Cardiac muscle
Brain tissue
All of these
All
L-Arginine/L-Citrulline can be used for increasing sperm count and motility.
T/F
True
Which amino acid serves as an energy substrate for spermatozoa and has antioxidant properties for testicles and sperm?
Arginine
Carnitine
Lysine
Taurine
Carnitine