5.2: Streptococcus Flashcards

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1
Q

Streptococcus is a Gram-___1___, round bacterium that tends to ___2___ structures.

A
  1. positive
  2. link to other bacteria in chain-like
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2
Q

True or False: Streptococcus is a Gram-negative round bacterium.

A

FALSE. Streptococcus is a Gram-positive round bacterium.

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3
Q

Strep is ___1___, meaning it cannot breakdown peroxides, and is often cultured on ___2___.

A
  1. catalase negative
  2. blood agar plates (BAP)
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4
Q

Strep is catalase negative, meaning it cannot breakdown what?

A

peroxides

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5
Q

True or False: Since there are numerous subtypes of Streptococcus, culturing on BAP is perhaps the quickest way to identify and classify a potential Streptococcus microbe based on its hemolytic properties.

A

True.

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6
Q

Describe Alpha-hemolysis.

A

Alpha-hemolysis presents as a greenish-brown discoloration surrounding the bacterial colony, the result of the partial decomposition of hemoglobin found within blood cells.

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7
Q

Alpha-hemolysis is characteristic of what strain of Streptococcus?

A

Alpha hemolysis is characteristic of Streptococcus pneumonia, so it can be used as a diagnostic feature in the identification of the bacterial strain.

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8
Q

Describe Beta-hemolysis.

A

Beta-hemolysis is classified as the capacity of a microbe to completely lyse red blood cells. The resulting lysis presents as a distinct zone of clearing around the growing colony.

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9
Q

Beta-Hemolysis is characteristic of what strain of Streptococcus?

A

Beta-hemolysis is characteristic of Streptococcus pyogenes and some strains of Staphylococcus aureus.

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10
Q

Describe Gamma-Hemolysis.

A

Gamma-hemolysis designates the absence or lack of hemolytic activity, and the resulting colonies are often white/tan in color growing on the red background color of the unaffected blood agar plate.

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11
Q

Gamma-Hemolysis is characteristic of what strain of Streptococcus?

A

Gamma hemolysis is a characteristic of Enterococcus faecalis.

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12
Q

______ Streptococcus can be divided into antigenic groups known as Lancefield groupings.

A

Beta-hemolytic

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13
Q

Beta-hemolytic Streptococcus can be divided into antigenic groups known as ______.

A

Lancefield groupings

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14
Q

While all bacteria within this system, Lancefield groupings, are ___1___ and ___2___, the distinction lies in the carbohydrate composition of bacterial antigens located in the ___3___.

A
  1. catalase-negative
  2. coagulase-negative
  3. cell wall
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15
Q

Streptococcus pyogenes, which belongs to Group___1___, is the causative agent behind more than ___2___ of human streptococcal infections resulting in ___3___, ___4___, or ___5___.

A
  1. A
  2. 90 percent
  3. pharyngitis
  4. scarlet fever
  5. rheumatic fever
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16
Q

Describe Streptococcal pharyngitis (strep throat).

A

Streptococcal pharyngitis (strep throat) is a Group A disease characterized by fever, enlargement of lymph nodes in the neck, and a reddening within the lining of the throat surface tissue causing soreness and discomfort.

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17
Q

Strep throat can also lead to additional complications within what areas?

A

Strep throat can also lead to additional complications within the ear, lung, or sinus cavities.

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18
Q

If left untreated, strep throat can progress to ______.

A

rheumatic fever

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19
Q

Rheumatic fever occurs in approximately ___1___ percent of untreated cases of Streptococcal ___2___, presenting approximately ___3___ weeks post-infection.

A
  1. 3
  2. pharyngitis
  3. 2 to 3
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20
Q

What are the symptoms of Rheumatic fever and what is the most dangerous one? Also which organ does it target?

A

Rheumatic fever presents with:
1. An inflammation of the joints
2. Involuntary jerking movements
3. The development of pea-sized nodules beneath the skin
4. Reddened areas with raised edges over the surface of the skin.

The most serious development is the damage to heart valves as the bacteria targets this organ.

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21
Q

What is Rheumatic Fever Treated with and when must it occur?

A

Treatment with penicillin is essential to combat this infection, but treatment must occur promptly at the onset of symptoms.

22
Q

In Rheumatic Fever, what causes the inflammation of heart tissue?

A

Inflammation of the heart tissues occurs due to the similarities between antigens found within heart tissue and those belonging to Streptococcus. Antibodies meant to destroy the microbe have the potential to (undesirably) cross-react with the heart tissue, causing further inflammation and damage.

23
Q

Streptococcal septicemia (blood poisoning) is caused by a Group ______ Streptococcus infection of the blood but can also secondarily infect other surrounding tissues.

A

B

24
Q

True or False: In Streptococcal septicemia (blood poisoning), the host response (fever, increased heart rate, etc.) to the infectious foreign agent and not just the foreign microbe alone can be equally damaging to the body.

A

True

25
Q

Septicemia is a serious, life-threatening infection that worsens quickly due to its ______ nature.

A

systemic

26
Q

Septicemia can arise from infections in the ___1___, ___2___, or ___3___ and may precede or accompany ___4___ or ___5___.

A
  1. lungs
  2. abdomen
  3. urinary tract
  4. meningitis
  5. endocarditis
27
Q

What are the symptoms of Septicemia?

A

Septicemia often presents with fever, chills, rapid breathing, and an increased heart rate. Symptoms rapidly progress to shock (with fever or hypothermia) and a decrease in blood pressure.

28
Q

What are some of the treatments often involved with Septicemia?

A

Treatment often involves antibiotics, IV fluids, and oxygen.

29
Q

Septicemia is not limited to just Streptococcus but can also be caused by other foreign microbes including species of ___1___, ___2___, and ___3___.

A
  1. E. coli,
  2. Pseudomonas
  3. Klebsiella
30
Q

True or False: Septicemia is not limited to just Streptococcus but can also be caused by other foreign microbes including species of E. coli, Pseudomonas, and Klebsiella

A

True

31
Q

What does Catalase-Negative mean?

A

Can not breakdown peroxides.

32
Q

The name Streptococcus actually means ______ in Greek.

A

Twisted Chain

33
Q

Strep has a Hyaluronic Acid Capsule that helps it it do what? Why does this happen?

A

The Hyaluronic Acid Capsule helps camouflage it. This happens because Hyaluronic Acid is also present naturally in the body’s own connective tissues.

34
Q

What groups of the Lancefield Groupings are associated with human disease?

A

Group A, B, & D

35
Q

Streptococcus Agalactiae is part of what Lancefield Group?

A

Group B

36
Q

Strep Throat, Scarlet Fever, Impetigo, Toxic Shock Syndrome, Cellulitis and Necrotizing Fasciitis are caused by Streptococcus ______.

A

Pyogenes

37
Q

How is Streptococcus Pharyngitis (Strep Throat) tested/diagnosed?

A

The throat is swabbed and then the sample will be applied to antibody mixture. If the antigen is present and it binds to the antibodies the test is positive.

38
Q

What is Otitis?

A

An ear infection.

39
Q

What is Sinusitis?

A

An infection in sinus

40
Q

What gives Streptococcus Pyogenes its virulence?

A

An M Protein found on its surface.

41
Q

What does G.A.S. stand for?

A

Groups A Streptococcus

42
Q

What does G.B.S. stand for?

A

Groups B Streptococcus

43
Q

What is being shown in the picture?

A

Streptococcus. (A) Staining of a step + sample, notice the characteristic formation of chains of cocci. (B) Patient presents with swelling within the throat and red patches at the site of inflammation, which are associated with soreness and discomfort.

44
Q

Group D has been reclassified into the genus of ______.

A

enterococcus

45
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A
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A
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A
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A
50
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A
51
Q
A
52
Q
A