5- Procedural LTM Flashcards

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1
Q

2 disorders of the basal ganglia

A

Huntington’s disease and Parkinson’s disease

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2
Q

Cause of Huntington’s disease

A

Inherited

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3
Q

Location of atrophy in Huntington’s disease

A

Basal ganglia

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4
Q

Early symptoms of Huntington’s disease

A

Difficulty concentrating and memory lapses

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5
Q

Later symptoms of Huntington’s disease

A

Involuntary jerking

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6
Q

Cause of Parkinson’s disease

A

Combination of genetic and environmental factors

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7
Q

Location of atrophy causing PD

A

Substantia nigra

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8
Q

Physical symptoms of PD

A

Rigor (muscle stiffness), tremor, bradykinesia (slow movement)

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9
Q

Cognitive symptoms of PD

A

Memory problems and dementia

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10
Q

What did PD patients show in the ‘weather prediction’ task?

A

Impaired procedural memory, normal declarative memory

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11
Q

What did amnesiac patients show in the ‘weather prediction’ task?

A

Slow procedural learning, impaired declarative memory

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12
Q

What is indicated by a ‘double dissociation’ between procedural memory and declarative memory?

A

Neural bases of declarative and procedural memory are mutually exclusive

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13
Q

What was the impact on episodic memory and procedural memory in anterograde amnesia and what did this show?

A

Impaired episodic memory and intact procedural memory
Showed dissociation between episodic (declarative) and procedural memory systems

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14
Q

What does initial involvement of the hippocampus in the ‘weather prediction task’ suggest?

A

Episodic/explicit task component

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15
Q

What does later involvement of the striatum in the ‘weather prediction task’ suggest?

A

Implicit internalisation of task

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16
Q

What dissociation does the ‘weather prediction task’ show?

A

Dissociation between episodic (declarative) and procedural memory systems

17
Q

Why is slow procedural learning in amnesia seen?

A

Due to impaired episodic memory

18
Q

How is procedural LTM shown to be stored in the striatum?

A

Shown by Huntington’s and Parkinson’s disease

19
Q

Are declarative and procedural memory systems distinct?

A

Yes

20
Q

When is a double dissociation seen?

A

Between PD patients and episodic amnesia