5 - Deep Brain Stimulation Flashcards
1
Q
2 phases of DBS
A
Electrode to brain
Pulse generator
DBS adjustment
2
Q
How does DBS work
A
Antidromic inhibition
Stimulation of inhibitory nerves
3
Q
What is the DBS target for Parkinson’s disease
A
Subthalamic Nucleus
4
Q
What is the DBS target for tremors
A
Thalamus
5
Q
What is the DBS target for dystonia
A
Globus pallidus interna
6
Q
4 classic features of parkinson’s
A
Resting tremor
Postural instability Bradykinesia
Rigidity
7
Q
Problem with DBS
A
Doesn’t give you the dopamine so movement is okay but do not feel good
8
Q
What is dystonia
A
• Sustained or repetitive muscle contractions result in twisting and repetitive movements or abnormal fixed postures.
9
Q
Cause of dystonia
A
DYT1 mutation
10
Q
Less common indications of DBS
A
Neuropathic pain, poorly controlled epilepsy, refractory depression
