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BB2 > 25 - Cannabis > Flashcards

25 - Cannabis Flashcards

1
Q

What causes a shadow plaque to form in MS

A

Migroglia –> Lymphocytes –> Active rim –> Macrophages where areas of damage –> Demyelination –> Astrocytic scar OR oligodendrocyte precursor cells –>Shadow plaque

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2
Q

How many cannabinoid chemicals in cannabis

A

113

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3
Q

Where are CB1 receptors

A

Highly abundant in the nervous system and vascular, adipose tissues, GI tract

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4
Q

Where are CB2 receptors

A

Immune system, function not clear

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5
Q

Anandamide

A

Endocannabinoid
formed from multiple pathways from NAPE
Includes phospholipase A2
Higher affinity

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6
Q

2-Arachidonoyl glycerol

A

Endocannabinoid
Lower affinity
From arachidonic acid containing DAG by action of diacylglycerol lipase

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7
Q

Sativex

A

Used to treat spasticity

= Mix of THC and cannabidiol 1:1

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8
Q

Pleasant effects of cannabis

A

Euphoria
Happiness
Relaxation
Slow co-ordination

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9
Q

Unpleasant effects of cannabis

A

Increase appetite
Impair judgement
Paranoia
Worsen schizophrenia

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BB2 (27 decks)

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