4.3 Anti-anginal agents

Question 1

Angina is described as…

Answer 1

Oxygen and nutrients in blood are insufficient to meet demands of heart ‘heart-ache’

Can be caused by Coronary Artery Disease or Ischemic heart disease

Question 2

Coronary Artery Disease is described as…

Answer 2

Any one of the abnormal conditions that affect the arteries of the heart and produce pathological effects, especially a reduced supply of oxygen and nutrients to the myocardium

Question 3

Ischemic Heart Disease is described as…

Answer 3

Poor blood supply to the heart via the coronary arteries

Question 4

There are 3 types of angina, what are they?

Answer 4

• Chronic stable angina
• Unstable angina
• Vasospastic angina

Question 5

This type of angina is AKA effort angina or classic angina

It occurs as a result of atherosclerosis and can be triggered by exertion or other stressors

Answer 5

Chronic stable angina

Question 6

This type of angina is the most dangerous, as it is the clinical presentation of CAD.

AKA preinfarction angina

Answer 6

Unstable angina

Question 7

This type of angina results from the spasm of the layer of smooth muscle that surrounds the atherosclerotic coronary arteries. It often occurs at rest without any precipitating cause

AKA Variant or Prinzmetal’s angina

Answer 7

Vasospastic angina

Question 8

3 examples of antianginal drugs include…

Answer 8

Nitrates
Beta-blockers
Calcium channel blockers

Question 9

The objectives of drug therapy for angina include…

Answer 9

Increase blood flow to ischemic muscle
Decrease myocardial oxygen demand