4.2 Antidysrhythmic agents Flashcards
Cardiac dysrhythmias are…
A disturbance in
- Electrical impulse formation
- Electrical impulse conduction
- or both
causes abnormal rhythms of the heart
Antidysrhythmic agents are…
Drugs used for the treatment and prevention of disturbances in cardiac rhythm
The Vaughan Williams classification is based on what?
the effect produced by the agent on the ‘action potential’
Class 1 (a,b,c) include which kind of drugs?
Sodium channel blockers
Class II include which kind of drugs?
Beta-Blocking agents
Class III drugs include which kind of drugs?
Drugs which increase the action potential duration
Class IV drugs include which kind of drugs?
Calcium channel blockers
Quinidine and lidocaine are in which drug class?
Class I
Atenolol and Metoprolol are in which drug class?
Class II
Amiodarone is in which drug class?
Class III
Diltiazem is in which drug class?
Class IV
Atrial fibrillation, premature atrial contractions, premature ventricular contractions, ventricular tachycardia, and Wolff-Parkinson-White syndrome are the indications for which drug class?
Class Ia
ventricular dysrhythmias are the only indication for which drug class?
Class Ib
severe ventricular dysrhythmias, and occasionally in atrial fibrillation/flutter, are the indications for which drug class?
Class Ic
Which drug class contains general myocardial depressants for both supraventricular and ventricular dysrhythmias?
Class II
