3.4 Cholinergic Blocking Agents Flashcards
The function of cholinergic blocking agents is…
To block/inhibit the actions of ACh in the parasympathetic nervous system
Cholinergic blocking agents are AKA…
Parasympatholytics
Parasympatholytics are similar to…
Sympathomimetics
Anticholinergic drugs work to _____ acetylcholine at the _______ receptors
block, muscarinic
Cholinergic blockers are known as what kind of antagonist?
Competitive
Anticholinergic Respiratory effects on the respiratory system include…
Decreases secretions from:
- nose,
- mouth
- pharynx
- bronchi
Relaxes smooth muscles in:
- bronchi and bronchioles
Respiratory anticholinergic agents are used to treat…
Exercise-induced bronchospasms
Chronic bronchitis
Asthma
Chronic obstructive pulmonary disease (COPD)
The parasympathetic nervous system controls which aspects of the GI tract?
gastric secretions and smooth muscles that produce gastric motility
Anticholinergic effects on the GI tract include:
- Decreased secretions
- Relaxation of smooth muscle
- Decreased GI motility and peristalsis (reduce diarrhea)
Gastrointestinal anticholinergic agents are used to treat…
- Peptic ulcer disease
- Irritable bowel disease
- GI hypersecretory states
What are the effects of anticholinergic agents on the Genitourinary system?
- Relaxed detrusor muscles of the bladder
- Increased constriction of the internal sphincter
- Reflex neurogenic bladder
- Incontinence
Symptoms of anticholinergic toxicity
HDRMB
Hot as a Hare:
Dry as a Bone: dries up secretions
Red as a Beet:
Mad as a Hatter: delusional
Blind as a Bat: dilated pupils
Which anticholinergic drug is used primarily in the management of CV disorders such as symptomatic bradycardia, and in relaxing the ciliary muscle of the eye?
Atropine
Which anticholinergic drug is used to prevent n+v and motion sickness?
Scopolamine
Which anticholinergic drug is mainly used to treat the symptoms of chronic obstructive pulmonary disease and asthma
Ipratropium/atrovent
Which anticholinergic drug is mainly used to treat an overactive bladder?
Oxybutynin
Which anticholinergic drug is used to treat movement disorders like parkinsonism and dystonia?
Benztropine
Which side effect caused by cholinergic-blocking drugs would make it hard to operate cars and other machinery?
Blurred vision
Why might a client on cholinergic-blocking drugs want to wear sunglasses?
They could experience sensitivity to light
What is the risk regarding geriatric clients on anticholinergic drugs?
heatstroke due to effects on heat-regulating mechanisms
Clients on cholinergic-blocking drugs should limit what 3 things?
Strenuous exercise
Excess heat
Physical exertion
Nurses should enforce the importance of ______ and ______ intake
fluid, salt
What are some therapeutic effects of cholinergic-blocking drugs for Parkinson’s clients?
fewer tremors and decreased salivation
and drooling
What are some therapeutic effects of cholinergic-blocking drugs for clients with peptic ulcer disease?
decreased abdominal pain
What are some therapeutic effects of cholinergic-blocking drugs for clients with urological diseases?
improved urinary patterns, less hypermotility, increased time between voiding
