3C: Cardiac Meds Flashcards
What do venodilators do?
Reduce preload by decreasing volume to increase length tension relationships - nitrates
What do arteriodilators do?
Reduce after load - Hydralazine
What is the use of Hydralazine?
HTN, CHF
What is the action of Hydralazine?
Direct vasodilation to decrease peripheral resistance
What are the adverse effects of Hydralazine?
Orthostatic hypotension, increased HR
What process do ACE inhibitors block?
In CHF, blood flow to the kidneys stimulates the release of renin, which initiates a chain of events causing the body to absorb increasing amounts of fluids, which will then exacerbate CHF
What are the uses of Vasotec, Accupril, and Lisinopril?
CHF, HTN, ventricular remodeling after an acute event
What is the action of Vasotec, Accupril, and Lisinopril?
Inhibit vasoconstriction and water/sodium retention
What are the adverse effects of of Vasotec, Accupril, and Lisinopril?
Minor - GI disturbances, skin rashes and dry mouth
What other patient population could benefit from Vasotec, Accupril, and Lisinopril?
Without CHF if they have a low EF < 40%
What is the use of Avapro and Cozar?
HTN, CHF, can prevent kidney failure in patients with DM
What is the action of Avapro and Cozar?
Angiotensin II causes blood vessels to constrict. ARBS block binding at those receptors so vessel will dilate or at least not constrict
What are the adverse effects of Avapro and Cozar?
Cough, hyperkalemia, low BP, dizziness, headache, drowsiness - need to be mindful of potassium intake
What is the use of Niacin?
Decrease LDL and triglycerides
What is the action of Niacin?
Decrease LDL synthesis
