2S [LAB]: IM

Question 1

Who discovered that serum from patient with IM contained heterophile antibodies which agglutinated sheep RBCs?

Answer 1

Paul & Bunnell

Question 2

Introduced the adsorption of serum, retained heterophile antibodies, and removed Forssman antibodies

Answer 2

Davisohn

Question 3

Virus that causes infectious mononucleosis

Answer 3

Epstein-Barr virus

Question 4

A blood smear of patient infected with IM will exhibit the presence of an enlarged atypical lymphocytes called ___

Answer 4

Downey cells

Question 5

Positive result for IM rapid slide test

Answer 5

Visible red cell agglutinates

Question 6

A presumptive test for IM that uses a 2% Sheep RBC suspension with varying dilution of patient’s inactivated serum

Answer 6

Paul-Bunnell Test

Question 7

Positive result for Paul-Bunnell Test

Answer 7

Clumping of red cells

Question 8

Significant titer for Paul-Bunnell Test that is reported as positive

Answer 8

1:56 or higher

Question 9

Significant titer for Paul-Bunnell Test that is reported as presumptive for PB titer

Answer 9

1:224

Question 10

To determine the specific heterophile antibody present in the sample after the Paul-Bunnell test, what differential test must be performed?

Answer 10

Davidsohn differential test