2S [LAB]: Autoimmune Disorders

Question 1

A condition that occurs when a body’s immune response mistakenly attacks and destroys its own body tissues

Answer 1

Autoimmune disease

Question 1

A useful method for screening patients suspected with SLE

Answer 1

Antinuclear antibodies (ANA) test

Question 2

Positive result for SLE latex slide test

Answer 2

Visible aggregates within 2 mins

Question 3

A non-organ specific type of autoimmune disorder that affects the lining of the joints, thereby causing a painful swelling that can eventually lead to bone erosion and joint deformity

Answer 3

Rheumatoid arthritis

Question 4

Ig class most commonly associated with rheumatoid factor

Answer 4

IgM (IgA and IgG may also occur)

Question 5

Hemagglutination method for the qualitative and semi-quantitative detection of RF in human serum

Answer 5

Rose Waaler Test

Question 6

Present in only a quarter to half of patients before or at diagnosis

Answer 6

Anti-cyclic citrullinated peptide

Question 7

T/F: A negative result for anti-cyclic citrullinated peptide rules out rheumatoid arthritis

Answer 7

False