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Elsevier Bacteriology (RVSP) > 27. Anaerobic Gram-positive Bacillus > Flashcards

27. Anaerobic Gram-positive Bacillus Flashcards

1
Q

Location of spores produced by Clostridium spp.

A

Terminal or central

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2
Q

Clostridium spp. that causes gas gangrene and food poisoning

A

Clostridium perfringens

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3
Q

Clostridium spp. that causes tetanus

A

Clostridium tetani

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4
Q

Clostridium spp. that causes botulism

A

Clostridium botulinum

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5
Q

Clostridium spp. that causes antibiotic-associated diarrhea and colitis

A

Clostridium difficile

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6
Q

Motility of C. perfringens

A

Nonmotile

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7
Q

Disease caused by C. perfringens

A

Gas gangrene

Food poisoning

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8
Q

Motility of C. tetani

A

Motile

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9
Q

Disease caused by C. tetani

A

Tetanus

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10
Q

Treatment for gas gangrene caused by C. perfringens

A

Hyperbaric O2 chamber
Antibiotics
Surgical (debridement)

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11
Q

Treatment of Tetanus

A

Antitoxin

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12
Q

Prophylaxis for tetanus

A

Vaccination (toxoid)

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13
Q

Motility of C. botulinum

A

Motile

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14
Q

Toxin produced by C. botulinum

A

Botulism neurotoxin (BoTN)

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15
Q

Mechanism of botulism neurotoxin

A

Blocks Ach release at the neuromuscular junction and causes inhibition of muscle contraction

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16
Q

How to destroy Botulinum toxin in food?

A

Boiling the food

17
Q

MOT of infant botulism

A

Ingestion of food containing spores

18
Q

Most common food source of C. botulinum spores

A

Honey

19
Q

Motility of C. difficile

A

Motile

20
Q

Enterotoxins released by C. difficile

A

A and B

21
Q

Disease caused by C. difficile

A

Pseudomembranous colitis/antibiotic-associated colitis

22
Q

Treatment for pseudomembranous colitis

A

Metronidazole

Vancomycin

23
Q

Diagnostic tests for pseudomembranous colitis

A
  • immunoassay of stool extract for C. difficile toxins

- colonoscopy showing pathologic findings of pseudomembranous colitis

24
Q

Microscopic characteristics of Clostridium spp.

A

Gram-positive bacillus

usually large bacilli

Elsevier Bacteriology (RVSP) (34 decks)

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